(Q34522863)

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Secretory lysosomes

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scholarly article

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Europe PubMed Central

2 August 2017

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Europe PubMed Central

Secretory lysosomes (English)

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Europe PubMed Central

2 August 2017

lysosomal enzyme secretion involved in inflammatory response

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

Gillian Griffiths

2

1 reference

Europe PubMed Central

2 August 2017

author name string

Emma J Blott

1

1 reference

Europe PubMed Central

2 August 2017

publication date

1 February 2002

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Europe PubMed Central

2 August 2017

Nature Reviews Molecular Cell Biology

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Europe PubMed Central

2 August 2017

3

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Europe PubMed Central

2 August 2017

122-131

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Europe PubMed Central

2 August 2017

2

1 reference

Europe PubMed Central

2 August 2017

https://scigraph.springernature.com/pub.10.1038/nrm732

0 references

The melanosome: membrane dynamics in black and white

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Cell-mediated extracellular acidification and bone resorption: evidence for a low pH in resorbing lacunae and localization of a 100-kD lysosomal membrane protein at the osteoclast ruffled border

1 reference

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31 March 2020

Molecules relevant for T cell-target cell interaction are present in cytolytic granules of human T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Platelet dense granules: structure, function and implications for haemostasis.

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Molecular and cellular biology of mast cells and basophils

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Biogenesis of phagolysosomes proceeds through a sequential series of interactions with the endocytic apparatus

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

The src-family protein-tyrosine kinase p59hck is located on the secretory granules in human neutrophils and translocates towards the phagosome during cell activation

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Molecular control of neural crest formation, migration and differentiation

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Melanosomes are specialized members of the lysosomal lineage of organelles.

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Secretory Lysosome Biogenesis in Cytotoxic T Lymphocytes from Normal and Chediak Higashi Syndrome Patients

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

The biogenesis of lysosomes: is it a kiss and run, continuous fusion and fission process?

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

The molecular machinery for lysosome biogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

A receptor for the selective uptake and degradation of proteins by lysosomes

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Regulation of lamp2a levels in the lysosomal membrane

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

A role for a 70-kilodalton heat shock protein in lysosomal degradation of intracellular proteins

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Regulated secretion of conventional lysosomes

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Plasma membrane repair is mediated by Ca(2+)-regulated exocytosis of lysosomes

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Direct vesicular transport of MHC class II molecules from lysosomal structures to the cell surface

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

B lymphocytes secrete antigen-presenting vesicles

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Distinct protein sorting and localization to premelanosomes, melanosomes, and lysosomes in pigmented melanocytic cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

The activation of resting lymphocytes is accompanied by the biogenesis of lysosomal organelles

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Serial killing by cytotoxic T lymphocytes: T cell receptor triggers degranulation, re-filling of the lytic granules and secretion of lytic proteins via a non-granule pathway

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Caenorhabditis elegans rab-3 mutant synapses exhibit impaired function and are partially depleted of vesicles.

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Differential sorting of lysosomal enzymes out of the regulated secretory pathway in pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Mannose 6-phosphate receptors are sorted from immature secretory granules via adaptor protein AP-1, clathrin, and syntaxin 6-positive vesicles

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Asparagine-linked oligosaccharides protect Lamp-1 and Lamp-2 from intracellular proteolysis

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

The formation of immunogenic major histocompatibility complex class II-peptide ligands in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Transport of peptide-MHC class II complexes in developing dendritic cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Dendritic cells: specialized and regulated antigen processing machines

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Adaptor-related proteins

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Characterization of GMP-17, a granule membrane protein that moves to the plasma membrane of natural killer cells following target cell recognition

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

The trans-Golgi network: a late secretory sorting station

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Structure and function of the mannose 6-phosphate/insulinlike growth factor II receptors

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Mannose 6-phosphate-independent targeting of lysosomal enzymes in I-cell disease B lymphoblasts

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Degranulation plays an essential part in regulating cell surface expression of Fas ligand in T cells and natural killer cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

The tyrosinase gene and oculocutaneous albinism type 1 (OCA1): A model for understanding the molecular biology of melanin formation

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Melanocyte differentiation marker gp75, the brown locus protein, can be regulated independently of tyrosinase and pigmentation

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

A di-leucine-based motif in the cytoplasmic tail of LIMP-II and tyrosinase mediates selective binding of AP-3.

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Sorting and targeting of melanosomal membrane proteins: signals, pathways, and mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

PDZ domain protein GIPC interacts with the cytoplasmic tail of melanosomal membrane protein gp75 (tyrosinase-related protein-1)

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Role of calcium influx in cytotoxic T lymphocyte lytic granule exocytosis during target cell killing

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Actin- and microtubule-dependent organelle motors: interrelationships between the two motility systems.

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Visualization of melanosome dynamics within wild-type and dilute melanocytes suggests a paradigm for myosin V function In vivo

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Synaptotagmin VII regulates Ca(2+)-dependent exocytosis of lysosomes in fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Synaptotagmin II negatively regulates Ca2+-triggered exocytosis of lysosomes in mast cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

SNARE-mediated membrane fusion

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Rab proteins as membrane organizers

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Isolation of a murine cDNA clone encoding Rab19, a novel tissue-specific small GTPase

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Soluble NSF attachment protein receptors (SNAREs) in RBL-2H3 mast cells: functional role of syntaxin 4 in exocytosis and identification of a vesicle-associated membrane protein 8-containing secretory compartment

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Relocation of the t-SNARE SNAP-23 from lamellipodia-like cell surface projections regulates compound exocytosis in mast cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Rat Basophilic Leukemia Cells Express Syntaxin-3 and VAMP-7 in Granule Membranes

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Small Gtpase rab3A is associated with melanosomes in melanoma cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Rab3a and SNARE proteins: potential regulators of melanosome movement

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Rab3D, a small GTPase, is localized on mast cell secretory granules and translocates to the plasma membrane upon exocytosis.

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

A small GTP-binding protein dissociates from synaptic vesicles during exocytosis.

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Diffuse vesicular distribution of Rab3D in the polarized neuroendocrine cell line AtT-20.

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Comparison of the effects on secretion in chromaffin and PC12 cells of Rab3 family members and mutants. Evidence that inhibitory effects are independent of direct interaction with Rabphilin3

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Two genes are responsible for Griscelli syndrome at the same 15q21 locus.

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Defective granule exocytosis in Rab27a-deficient lymphocytes from Ashen mice

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Rab27a is required for regulated secretion in cytotoxic T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

A mutation in Rab27a causes the vesicle transport defects observed in ashen mice

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Rab geranylgeranyl transferase alpha mutation in the gunmetal mouse reduces Rab prenylation and platelet synthesis

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Normal and abnormal secretion by haemopoietic cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Mutations in Mlph, encoding a member of the Rab effector family, cause the melanosome transport defects observed in leaden mice

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Identification of a novel myosin-Va mutation in an ataxic mutant rat, dilute-opisthotonus

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Functions of unconventional myosins

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Rab27a regulates the peripheral distribution of melanosomes in melanocytes

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Identification and mutation analysis of the complete gene for Chediak-Higashi syndrome

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Identification of mutations in two major mRNA isoforms of the Chediak-Higashi syndrome gene in human and mouse

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Analysis of the lysosomal storage disease Chediak-Higashi syndrome

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Mouse models of Hermansky Pudlak syndrome: a review

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Electron microscopic evidence for externalization of the transferrin receptor in vesicular form in sheep reticulocytes

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes.

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

31 March 2020

Activated Platelets Release Two Types of Membrane Vesicles: Microvesicles by Surface Shedding and Exosomes Derived From Exocytosis of Multivesicular Bodies and -Granules

1 reference

https://api.crossref.org/works/10.1038%2FNRM732

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Europe PubMed Central

2 August 2017

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Europe PubMed Central

2 August 2017

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