(Q34526939)

2 August 2017

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title

Genetic studies, clinical heterogeneity, and disease outcome studies in rheumatoid arthritis (English)

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2 August 2017

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George Moxley

1

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2 August 2017

Harley J Cohen

series ordinal

2

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2 August 2017

publication date

1 February 2002

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Rheumatic Diseases Clinics of North America

2 August 2017

published in

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2 August 2017

volume

28

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2 August 2017

issue

1

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2 August 2017

page(s)

39-58

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Compound heterozygosity of HLA-DR4 and DR1 antigens in Asian Indians increases the risk of extra-articular features in rheumatoid arthritis

2 August 2017

cites work

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7 January 2021

Inhibition of the production and effects of interleukin-1 and tumor necrosis factor alpha in rheumatoid arthritis

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7 January 2021

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

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7 January 2021

Genetic analysis of multiplex rheumatoid arthritis families

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7 January 2021

Examination of HLA-DR4 as a severity marker for rheumatoid arthritis in Greek patients

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https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

HLA class II sequence polymorphisms and susceptibility to rheumatoid arthritis in Greeks. The HLA-DR beta shared-epitope hypothesis accounts for the disease in only a minority of Greek patients

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https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

TNF alpha--a pivotal role in rheumatoid arthritis?

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https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Tumour necrosis factor alpha gene polymorphisms in rheumatoid arthritis: association with susceptibility to, or severity of, disease?

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Relevant residues of DRbeta1 third hypervariable region contributing to the expression and to severity of rheumatoid arthritis (RA) in Mexicans

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https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Ancestral haplotypes: conserved population MHC haplotypes

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Both inherited HLA-haplotypes are important in the predisposition to rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

HLA-DRB1 alleles associated with susceptibility or resistance to rheumatoid arthritis, articular deformities, and disability in Mexican Americans.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Associations of HLA-DRB and -DQB genes with two and five year outcome in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Association of HLA alleles and clinical features in patients with synovitis of recent onset

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https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis

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https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Genetically determined factors as predictors of radiological change in patients with early symmetrical arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

The genotypic distribution of shared-epitope DRB1 alleles suggests a recessive mode of inheritance of the rheumatoid arthritis disease-susceptibility gene

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

HLA-DR alleles with naturally occurring amino acid substitutions and risk for development of rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Influence of the HLA-DR beta shared epitope on susceptibility to and clinical expression of rheumatoid arthritis in Chilean patients

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Novel genetic markers of rheumatoid arthritis in Chilean patients, by DR serotyping and restriction fragment length polymorphism analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Genetic typing of patients with inflammatory arthritis at presentation can be used to predict outcome

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Racial origin and its effect on disease expression and HLA-DRB1 types in patients with rheumatoid arthritis: a matched cross-sectional study

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Different gene loci within the HLA-DR and TNF regions are independently associated with susceptibility and severity in Spanish rheumatoid arthritis patients

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

HLA markers in a community-based rheumatoid arthritis series

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Influence of the HLA-DRB1 locus on susceptibility and severity in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

The association of HLA-DRB genes and the shared epitope with rheumatoid arthritis in Pakistan.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

The influence of HLA-DRB1 alleles and rheumatoid factor on disease outcome in an inception cohort of patients with early inflammatory arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

A re-analysis of the association between rheumatoid arthritis with and without extra-articular features, HLA-DR4, and DR4 subtypes

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

HLA and rheumatoid arthritis: a combined analysis of 440 British patients

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

The impact of HLA-DRB1*0405 on disease severity in Korean patients with seropositive rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

TNF-alpha gene polymorphism does not affect the clinical and radiological outcome of rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

HLA-DR1 and DRw6 association in DR4-negative rheumatoid arthritis patients

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Primary association of tumor necrosis factor-region genetic markers with susceptibility to rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Clinical expression of rheumatoid arthritis in Chilean patients.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Weak association between HLA-DR4 and rheumatoid arthritis in Chilean patients

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

The influence of HLA-DRB1 alleles encoding the DERAA amino acid motif on radiological outcome in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Interaction between tumor necrosis factor microsatellite polymorphisms and the HLA-DRB1 shared epitope in rheumatoid arthritis: influence on disease outcome

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Most African-American patients with rheumatoid arthritis do not have the rheumatoid antigenic determinant (epitope)

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Major histocompatibility complex variants and articular disease severity in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Tumor necrosis factor markers show sex-influenced association with rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Rheumatoid factor, HLA-DR4, and allelic variants of DRB1 in women with recent-onset rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Specific HLA-DR4-associated histocompatibility molecules characterize patients with seropositive juvenile rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

HLA-DRB1 typing in rheumatoid arthritis: predicting response to specific treatments

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Prognostic significance of complement alleles Bf and C4 in early rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Association of complement alleles C4AQ0 and C4B5 with rheumatoid arthritis in Koreans

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Does the age of onset of rheumatoid arthritis influence phenotype?: a prospective study of outcome and prognostic factors

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

The therapeutic effects of an engineered human anti-tumour necrosis factor alpha antibody (CDP571) in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

HLA-DRB1 genes and disease severity in rheumatoid arthritis. The MIRA Trial Group. Minocycline in Rheumatoid Arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Investigating the HLA component in rheumatoid arthritis: an additive (dominant) mode of inheritance is rejected, a recessive mode is preferred

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

The effect of HLA-DRB1 disease susceptibility markers on the expression of RA.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

HLA-DRB1 alleles associated with rheumatoid arthritis in Northern Italy: correlation with disease severity.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Association between HLA-DR antigens and rheumatoid arthritis in Arabs

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

HLA-DRB1*04 subtypes are associated with increased inflammatory activity in early rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

HLA-DR/DQ interaction in patients with erosive rheumatoid arthritis presenting articular and extraarticular disease manifestations

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Only weak association between disease severity and HLA-DRB 1 genes in a Swiss population of rheumatoid arthritis patients.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Association of the B-cell alloantigen DRw4 with rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Mixed lymphocyte cultures in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

HLA-DRB1 alleles in Greek rheumatoid arthritis patients and their association with clinical characteristics.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Rheumatoid-susceptible alleles of HLA-DRB1 are genetically recessive to non-susceptible alleles in the progression of bone destruction in the wrists and fingers of patients with RA.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

HLA class II and T-cell receptor beta chain polymorphisms in Belgian patients with rheumatoid arthritis: no evidence for disease association with the TCRBC2, TCRBV8 and TCRBV11 polymorphisms

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Association of HLA-DR with susceptibility to and clinical expression of rheumatoid arthritis: re-evaluation by means of genomic tissue typing

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Association of HLA-DR4 with a more progressive disease course in patients with rheumatoid arthritis. Results of a followup study

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Heat shock protein 70 gene polymorphisms in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

HLA markers and prediction of clinical course and outcome in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

An association between the natural course of shoulder joint destruction in rheumatoid arthritis and HLA-DRB1*0405 in Japanese patients

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

The relationship between HLA-DRB1 alleles and disease subsets of rheumatoid arthritis in Japanese.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Correlation between disease phenotype and genetic heterogeneity in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Homozygosity for the HLA-DRB1 allele selects for extraarticular manifestations in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

The influence of HLA-DRB1 genes on disease severity in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

The influence of sex on the phenotype of rheumatoid arthritis.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Meta-analysis reveals association between most common class II haplotype in full-heritage Native Americans and rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

A tumour necrosis factor alpha polymorphism is not associated with rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

HLA DRB1* typing and cartilage oligomeric matrix protein (COMP) as predictors of joint destruction in recent-onset rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

Association of HLA-DR4/Dw4 and DR2/Dw2 with radiologic changes in a prospective study of patients with rheumatoid arthritis. Preferential relationship with HLA-Dw rather than HLA-DR specificities

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

A prognostic index for erosive changes in the hands, feet, and cervical spines in early rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900068-1

7 January 2021

10.1016/S0889-857X(03)00068-1

Identifiers

DOI

1 reference

2 August 2017

1 reference