(Q34531013)

2 August 2017

title

5-Azacytidine acts directly on both erythroid precursors and progenitors to increase production of fetal hemoglobin (English)

1 reference

2 August 2017

R K Humphries

1

1 reference

2 August 2017

G Dover

2

1 reference

2 August 2017

N S Young

3

1 reference

2 August 2017

J G Moore

4

1 reference

2 August 2017

S Charache

5

1 reference

2 August 2017

T Ley

6

1 reference

2 August 2017

A W Nienhuis

7

1 reference

2 August 2017

language of work or name

English

0 references

publication date

1 February 1985

1 reference

Journal of Clinical Investigation

2 August 2017

published in

1 reference

2 August 2017

volume

75

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2 August 2017

issue

2

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2 August 2017

page(s)

547-557

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A single-base change at a splice site in a beta 0-thalassemic gene causes abnormal RNA splicing.

2 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423530

RNA processing errors in patients with beta-thalassemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423530

DNA methylation in the human γδβ-globin locus in erythroid and nonerythroid tissues

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423530

57 Sequencing end-labeled DNA with base-specific chemical cleavages

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423530

DNA methylation and regulation of the human beta-globin-like genes in mouse erythroleukemia cells containing human chromosome 11

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423530

Arabinosylcytosine Induces Fetal Hemoglobin in Baboons by Perturbing Erythroid Cell Differentiation Kinetics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423530

Human fetal to adult hemoglobin switching: changes in chromatin structure of the beta-globin gene locus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423530

Developmental activation of the H-2K gene is correlated with an increase in DNA methylation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423530

Treatment of sickle cell anemia with 5-azacytidine results in increased fetal hemoglobin production and is associated with nonrandom hypomethylation of DNA around the gamma-delta-beta-globin gene complex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423530

5-Azacytidine stimulates fetal hemoglobin synthesis in anemic baboons

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423530

Cellular mechanisms for increased fetal hemoglobin production in culture. Evidence for continuous commitment to fetal hemoglobin production during burst formation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423530

Transcription maps of polyoma virus-specific RNA: analysis by two-dimensional nuclease S1 gel mapping.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423530

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423530

Detection of specific sequences among DNA fragments separated by gel electrophoresis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423530

Stimulation of fetal hemoglobin synthesis in bone marrow cultures from adult individuals

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423530

Fetal hemoglobin restriction to a few erythrocytes (F cells) in normal human adults

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423530

Hemoglobin biosynthesis in individual erythropoietic bursts in culture. Studies of adult peripheral blood

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423530

Production of erythrocytes that contain fetal hemoglobin in anemia. Transient in vivo changes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423530

Cellular regulation of hemoglobin switching: evidence for inverse relationship between fetal hemoglobin synthesis and degree of maturity of human erythroid cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423530

Hemoglobin F synthesis in vitro: evidence for control at the level of primitive erythroid stem cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423530

Individual Variation in the Production and Survival of F Cells in Sickle-Cell Disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423530

Microscopic method for assaying F cell production: illustrative changes during infancy and in aplastic anemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423530

Cellular kinetics and iron utilization in bone marrow as observed by Fe59 radioautography.

7 July 2018

1 reference

12 December 2020

Human marrow cells capable of erythropoietic differentiation in vitro: definition of three erythroid colony responses

1 reference

12 December 2020

The rabbit β-globin gene contains a large insert in the coding sequence

1 reference

12 December 2020

Beta Thalassemia: mutations which affect processing of the beta-Globin mRNA precursor

1 reference

12 December 2020

Quantitation of hemoglobins within individual red cells: asynchronous biosynthesis of fetal and adult hemoglobin during erythroid maturation in normal subjects

1 reference

12 December 2020

5-Azacytidine Selectively Increases γ-Globin Synthesis in a Patient with β+Thalassemia

1 reference

12 December 2020

5-Azacytidine increases gamma-globin synthesis and reduces the proportion of dense cells in patients with sickle cell anemia

1 reference

12 December 2020

Perturbations in the erythroid marrow progenitor cell pools may play a role in the augmentation of HbF by 5-azacytidine

1 reference

12 December 2020

Augmentation of Fetal-Hemoglobin Production in Anemic Monkeys by Hydroxyurea

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI111731

1 reference

2 August 2017

1 reference

2 August 2017

1 reference