(Q34544560)

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Bioanalytical approaches to quantify "total" and "free" therapeutic antibodies and their targets: technical challenges and PK/PD applications over the course of drug development

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 August 2017

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Europe PubMed Central

Bioanalytical approaches to quantify "total" and "free" therapeutic antibodies and their targets: technical challenges and PK/PD applications over the course of drug development (English)

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Europe PubMed Central

PubMed publication ID

2 August 2017

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author name string

Jean W Lee

1

1 reference

Europe PubMed Central

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2 August 2017

Marian Kelley

2

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Europe PubMed Central

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2 August 2017

Lindsay E King

3

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Europe PubMed Central

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2 August 2017

Jihong Yang

4

1 reference

Europe PubMed Central

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2 August 2017

Hossein Salimi-Moosavi

5

1 reference

Europe PubMed Central

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2 August 2017

Meina T Tang

6

1 reference

Europe PubMed Central

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2 August 2017

Jian-Feng Lu

7

1 reference

Europe PubMed Central

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2 August 2017

John Kamerud

8

1 reference

Europe PubMed Central

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2 August 2017

Ago Ahene

9

1 reference

Europe PubMed Central

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2 August 2017

Heather Myler

10

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Europe PubMed Central

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2 August 2017

Cindy Rogers

11

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2 August 2017

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publication date

15 January 2011

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2 August 2017

The AAPS Journal

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Europe PubMed Central

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2 August 2017

13

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Europe PubMed Central

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2 August 2017

1

1 reference

Europe PubMed Central

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2 August 2017

99-110

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

https://scigraph.springernature.com/pub.10.1208/s12248-011-9251-3

0 references

Therapeutic monoclonal antibody concentration monitoring: free or total?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032085

7 July 2018

Novel approaches using alkaline or acid/guanidine treatment to eliminate therapeutic antibody interference in the measurement of total target ligand

1 reference

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1 reference

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Bioanalysis of recombinant proteins and antibodies by mass spectrometry

1 reference

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Factors affecting the antigen-antibody reaction

1 reference

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Antibody pharmacokinetics and pharmacodynamics

1 reference

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A critical review of vascular endothelial growth factor (VEGF) analysis in peripheral blood: is the current literature meaningful?

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The profile of soluble amyloid beta protein in cultured cell media. Detection and quantification of amyloid beta protein and variants by immunoprecipitation-mass spectrometry

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Some aspects of the mechanism of action of steroid hormones

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Development of a method for the sensitive and quantitative determination of hepcidin in human serum using LC-MS/MS.

1 reference

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27 October 2018

Towards absolute quantification of therapeutic monoclonal antibody in serum by LC-MS/MS using isotope-labeled antibody standard and protein cleavage isotope dilution mass spectrometry

1 reference

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27 October 2018

Ultra performance liquid chromatography isotope dilution tandem mass spectrometry for the absolute quantification of proteins and peptides

1 reference

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27 October 2018

Absolute quantification of monoclonal antibodies in biofluids by liquid chromatography-tandem mass spectrometry.

1 reference

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27 October 2018

Evaluation of a peptide ELISA for the detection of rituximab in serum.

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Fit-for-purpose method development and validation for successful biomarker measurement.

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27 October 2018

The application of target information and preclinical pharmacokinetic/pharmacodynamic modeling in predicting clinical doses of a Dickkopf-1 antibody for osteoporosis

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunopurification and mass spectrometric quantification of the active form of a chimeric therapeutic antibody in human serum

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel method for quantitative measurement of a biomarker in the presence of a therapeutic monoclonal antibody directed against the biomarker

1 reference

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12 December 2020

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An enzyme-linked immunosorbent assay for therapeutic drug monitoring of cetuximab

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoclonal antibody pharmacokinetics and pharmacodynamics

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1208/S12248-011-9251-3

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Dimensions Publication ID

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

ResearchGate publication ID

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