(Q34550600)

English

Combined NOX1/4 inhibition with GKT137831 in mice provides dose-dependent reno- and atheroprotection even in established micro- and macrovascular disease

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

Combined NOX1/4 inhibition with GKT137831 in mice provides dose-dependent reno- and atheroprotection even in established micro- and macrovascular disease (English)

1 reference

Europe PubMed Central

3 August 2017

author name string

Stephen P Gray

1

1 reference

Europe PubMed Central

3 August 2017

Jay C Jha

2

1 reference

Europe PubMed Central

3 August 2017

Kit Kennedy

3

1 reference

Europe PubMed Central

3 August 2017

Erik van Bommel

4

1 reference

Europe PubMed Central

3 August 2017

Phyllis Chew

5

1 reference

Europe PubMed Central

3 August 2017

Cedric Szyndralewiez

6

1 reference

Europe PubMed Central

3 August 2017

Rhian M Touyz

7

1 reference

Europe PubMed Central

3 August 2017

Harald H H W Schmidt

8

1 reference

Europe PubMed Central

3 August 2017

Mark E Cooper

9

1 reference

Europe PubMed Central

3 August 2017

Karin A M Jandeleit-Dahm

10

1 reference

Europe PubMed Central

3 August 2017

publication date

3 February 2017

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

60

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Europe PubMed Central

3 August 2017

5

1 reference

Europe PubMed Central

3 August 2017

927-937

1 reference

Europe PubMed Central

3 August 2017

https://scigraph.springernature.com/pub.10.1007/s00125-017-4215-5

0 references

Global estimates of the prevalence of diabetes for 2010 and 2030

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

NADPH oxidases in cardiovascular disease.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

NADPH oxidases: functions and pathologies in the vasculature

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

NADPH Oxidase 1 Plays a Key Role in Diabetes Mellitus–Accelerated Atherosclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

Genetic targeting or pharmacologic inhibition of NADPH oxidase nox4 provides renoprotection in long-term diabetic nephropathy

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

Diphenyleneiodonium inhibits NF-kappaB activation and iNOS expression induced by IL-1beta: involvement of reactive oxygen species

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

Apocynin is not an inhibitor of vascular NADPH oxidases but an antioxidant.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

Diphenyleneiodonium inhibits the cell redox metabolism and induces oxidative stress

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

Reactive Oxygen-Related Diseases: Therapeutic Targets and Emerging Clinical Indications

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

Pharmacological inhibition of NOX reduces atherosclerotic lesions, vascular ROS and immune-inflammatory responses in diabetic Apoe(-/-) mice

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

Decreased blood pressure in NOX1-deficient mice

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

Liver fibrosis and hepatocyte apoptosis are attenuated by GKT137831, a novel NOX4/NOX1 inhibitor in vivo.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

Irbesartan but not amlodipine suppresses diabetes-associated atherosclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

The endothelin receptor antagonist avosentan ameliorates nephropathy and atherosclerosis in diabetic apolipoprotein E knockout mice.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

Alagebrium reduces glomerular fibrogenesis and inflammation beyond preventing RAGE activation in diabetic apolipoprotein E knockout mice

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

Antiatherosclerotic and renoprotective effects of ebselen in the diabetic apolipoprotein E/GPx1-double knockout mouse

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

ACE2 deficiency modifies renoprotection afforded by ACE inhibition in experimental diabetes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

Transforming growth factor-β1-mediated renal fibrosis is dependent on the regulation of transforming growth factor receptor 1 expression by let-7b.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

Quinapril treatment abolishes diabetes-associated atherosclerosis in RAGE/apolipoprotein E double knockout mice.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

Prevention of accelerated atherosclerosis by angiotensin-converting enzyme inhibition in diabetic apolipoprotein E-deficient mice

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

Urotensin II receptor antagonism confers vasoprotective effects in diabetes associated atherosclerosis: studies in humans and in a mouse model of diabetes.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

Reactive Oxygen Species Can Provide Atheroprotection via NOX4-Dependent Inhibition of Inflammation and Vascular Remodeling

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

Podocyte-specific Nox4 deletion affords renoprotection in a mouse model of diabetic nephropathy

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

Metabolomics Reveals a Key Role for Fumarate in Mediating the Effects of NADPH Oxidase 4 in Diabetic Kidney Disease

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

Targeting NADPH oxidase with a novel dual Nox1/Nox4 inhibitor attenuates renal pathology in type 1 diabetes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

NADPH oxidase, NOX1, mediates vascular injury in ischemic retinopathy

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

RAGE-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

Nox4 is a major source of superoxide production in human brain pericytes.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

The Akt-FoxO3a-manganese superoxide dismutase pathway is involved in the regulation of oxidative stress in diabetic nephropathy

1 reference

https://api.crossref.org/works/10.1007%2FS00125-017-4215-5

21 January 2018

Combination Therapy with the Advanced Glycation End Product Cross-Link Breaker, Alagebrium, and Angiotensin Converting Enzyme Inhibitors in Diabetes: Synergy or Redundancy?

1 reference

https://pubmed.ncbi.nlm.nih.gov/28160092

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characteristics of the inhibition of NADPH oxidase activation in neutrophils by apocynin, a methoxy-substituted catechol

1 reference

https://pubmed.ncbi.nlm.nih.gov/28160092

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A noninvasive computerized tail-cuff system for measuring blood pressure in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/28160092

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00125-017-4215-5

1 reference

Europe PubMed Central

3 August 2017

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0 references

1 reference

Europe PubMed Central

3 August 2017

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