(Q34559510)

3 August 2017

title

Potent in vitro and in vivo antitoxoplasma activity of the lipid-soluble antifolate trimetrexate (English)

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3 August 2017

Allegra CJ

1

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3 August 2017

Kovacs JA

2

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3 August 2017

Drake JC

3

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3 August 2017

Swan JC

4

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3 August 2017

Chabner BA

5

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3 August 2017

Masur H

6

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3 August 2017

language of work or name

English

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publication date

1 February 1987

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Journal of Clinical Investigation

3 August 2017

published in

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3 August 2017

volume

79

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3 August 2017

issue

2

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3 August 2017

page(s)

478-482

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TECHNIQUES FOR STUDY OF RESISTANCE TO FOLIC ACID ANTAGONISTS

3 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424107

Mechanism of pyrimethamine resistance in recent isolates of plasmodium falciparum

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424107

Uptake and efficacy of trimetrexate (TMQ, 2,4-diamino-5-methyl-6-[(3,4,5-trimethoxyanilino)methyl] quinazoline), a non-classical antifolate in methotrexate-resistant leukemia cells in vitro

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424107

The interaction between Toxoplasma gondii and mammalian cells. I. Mechanism of entry and intracellular fate of the parasite

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424107

Inhibitor binding analysis of dihydrofolate reductases from various species.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424107

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424107

Mechanism of inhibition of dihydrofolate reductases from bacterial and vertebrate sources by various classes of folate analogues

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424107

Competitive protein binding assay for methotrexate

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424107

Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424107

A simple procedure for the synthesis of high specific activity tritiated (6S)-5-formyltetrahydrofolate

7 July 2018

1 reference

12 December 2020

Pneumocystis carinii Pneumonia: A Comparison Between Patients with the Acquired Immunodeficiency Syndrome and Patients with Other Immunodeficiencies

1 reference

12 December 2020

Dihydrofolate reductase. The stereochemistry of inhibitor selectivity

1 reference

12 December 2020

A re-evaluation of the competitive protein binding assay for methotrexate binding to dihydrofolate reductase

1 reference

12 December 2020

Transport routes utilized by L1210 cells for the influx and efflux of methotrexate

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI112837

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3 August 2017

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3 August 2017

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