(Q34564379)

3 August 2017

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title

Reflections on the discovery of nature's pathways to vitamin B12. (English)

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3 August 2017

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Scott AI

1

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3 August 2017

1 January 2001

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3 August 2017

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3 August 2017

1

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3 August 2017

212-227

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3 August 2017

3

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The biosynthesis of porphyrins, chlorophylls, and vitamin B12

3 August 2017

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How nature builds the pigments of life: the conquest of vitamin B12.

21 January 2018

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The total synthesis of vitamin B 12 .

21 January 2018

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Natural product synthesis and vitamin B12

21 January 2018

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Vitamin B12: Experiments Concerning the Origin of Its Molecular Structure

21 January 2018

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Sirohydrochlorin. Prosthetic group of a sulfite reductase enzyme and its role in the biosynthesis of vitamin B12

21 January 2018

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Biosynthesis of vitamin B12: identity of fragment extruded during ring contraction to the corrin macrocycle

21 January 2018

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Biosynthesis of vitamin B12: nature of the volatile fragment generated during formation of the corrin ring system

21 January 2018

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Site-directed mutagenesis and high-resolution NMR spectroscopy of the active site of porphobilinogen deaminase.

21 January 2018

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Identification of a cysteine residue as the binding site for the dipyrromethane cofactor at the active site of Escherichia coli porphobilinogen deaminase.

21 January 2018

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Evidence for a dipyrromethane cofactor at the catalytic site of E. coli porphobilinogen deaminase

21 January 2018

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Investigation into the nature of substrate binding to the dipyrromethane cofactor of Escherichia coli porphobilinogen deaminase.

21 January 2018

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Evidence that the pyrromethane cofactor of hydroxymethylbilane synthase (porphobilinogen deaminase) is bound to the protein through the sulphur atom of cysteine-242.

21 January 2018

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Evidence that the pyrromethane cofactor of hydroxymethylbilane synthase (porphobilinogen deaminase) is bound through the sulphur atom of a cysteine residue

21 January 2018

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Structure of porphobilinogen deaminase reveals a flexible multidomain polymerase with a single catalytic site

21 January 2018

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The Escherichia coli cysG gene encodes S-adenosylmethionine-dependent uroporphyrinogen III methylase

21 January 2018

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Expression of 9 Salmonella typhimurium enzymes for cobinamide synthesis. Identification of the 11-methyl and 20-methyl transferases of corrin biosynthesis

21 January 2018

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Cobalamin (vitamin B12) biosynthetic genes of Salmonella typhimurium

21 January 2018

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Biosynthesis of vitamin B12: isolation of precorrin-6x, a metal-free precursor of the corrin macrocycle retaining five S-adenosylmethionine-derived peripheral methyl groups

21 January 2018

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Precorrin-6x reductase from Pseudomonas denitrificans: purification and characterization of the enzyme and identification of the structural gene

21 January 2018

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Biosynthesis of vitamin B12 in Pseudomonas denitrificans: the biosynthetic sequence from precorrin-6y to precorrin-8x is catalyzed by the cobL gene product

21 January 2018

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Biosynthesis of vitamin B12: structure of precorrin-6x octamethyl ester

21 January 2018

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The final step in the biosynthesis of hydrogenobyrinic acid is catalyzed by the cobH gene product with precorrin-8x as the substrate

21 January 2018

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Biosynthesis of vitamin B 12

21 January 2018

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Biosynthesis of the corrin macrocycle of coenzyme B12 in Pseudomonas denitrificans

21 January 2018

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Studies on the biosynthesis of corrinoids and porphyrinoids. I. The labeling of oxygen of vitamin B12.

21 January 2018

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Assay, purification, and characterization of cobaltochelatase, a unique complex enzyme catalyzing cobalt insertion in hydrogenobyrinic acid a,c-diamide during coenzyme B12 biosynthesis in Pseudomonas denitrificans

21 January 2018

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Gene dissection demonstrates that the Escherichia coli cysG gene encodes a multifunctional protein

21 January 2018

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Evidence that the CysG protein catalyzes the first reaction specific to B12 synthesis in Salmonella typhimurium, insertion of cobalt

21 January 2018

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Genetic and sequence analysis of an 8.7-kilobase Pseudomonas denitrificans fragment carrying eight genes involved in transformation of precorrin-2 to cobyrinic acid

21 January 2018

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Biosynthesis of vitamin B12: factor IV, a new intermediate in the anaerobic pathway

21 January 2018

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How corrinoids are synthesized without oxygen: nature's first pathway to vitamin B12.

21 January 2018

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Biosynthesis of vitamin B12: concerning the identity of the two-carbon fragment eliminated during anaerobic formation of cobyrinic acid

21 January 2018

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Uroporphyrinogen III methylase catalyzes the enzymic synthesis of sirohydrochlorins II and IV by a clockwise mechanism

21 January 2018

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Biosynthesis of corrinoids. Origin of the methyl groups in vitamin B12

21 January 2018

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Biosynthesis of corrinoids. Uroporphyrinogen III as a precursor of vitamin B12

21 January 2018

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Biosynthesis of corrins. Cell-free system from Propionibacterium shermanii

21 January 2018

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Biosynthesis of vitamin B12: order of the later C-methylation steps

21 January 2018

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Reconstitution of apo-porphobilinogen deaminase: structural changes induced by cofactor binding

21 January 2018

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Enzymatic synthesis of dihydrosirohydrochlorin (precorrin-2) and of a novel pyrrocorphin by uroporphyrinogen III methylase

21 January 2018

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Enzymatic synthesis and structure of precorrin-3, a trimethyldipyrrocorphin intermediate in vitamin B12 biosynthesis

21 January 2018

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The Escherichia coli cysG gene encodes the multifunctional protein, siroheme synthase

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/TCR.1009

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3 August 2017

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PubMed ID

11895120