(Q34566566)

3 August 2017

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title

Of replications and refutations: the status of Alzheimer's disease genetic research (English)

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3 August 2017

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Bertram L

1

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PubMed ID

11898555

3 August 2017

Tanzi RE

series ordinal

2

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3 August 2017

1 September 2001

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Current Neurology and Neuroscience Reports

3 August 2017

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3 August 2017

1

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3 August 2017

442-450

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3 August 2017

5

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https://scigraph.springernature.com/pub.10.1007/s11910-001-0104-9

3 August 2017

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cites work

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS11910-001-0104-9

ApoE-4 and age at onset of Alzheimer's disease: the NIMH genetics initiative.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-001-0104-9

Genetic association of the low-density lipoprotein receptor-related protein gene (LRP), an apolipoprotein E receptor, with late-onset Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-001-0104-9

Alpha2 macroglobulin and the risk of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-001-0104-9

α2-Macroglobulin polymorphisms in Italian sporadic and familial Alzheimer's disease

21 January 2018

1 reference

12 December 2020

The genetic association between Cathepsin D and Alzheimer's disease.

1 reference

12 December 2020

Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium

1 reference

12 December 2020

SNPing away at complex diseases: analysis of single-nucleotide polymorphisms around APOE in Alzheimer disease

1 reference

12 December 2020

Association between an alpha(2) macroglobulin DNA polymorphism and late-onset Alzheimer's disease

1 reference

12 December 2020

Genetic association of an alpha2-macroglobulin (Val1000lle) polymorphism and Alzheimer's disease.

1 reference

12 December 2020

No association between an intronic biallelic polymorphism of the FE65 gene and Alzheimer's disease.

1 reference

12 December 2020

A polymorphism in the regulatory region of APOE associated with risk for Alzheimer's dementia.

1 reference

12 December 2020

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

1 reference

12 December 2020

Linkage studies in familial Alzheimer disease: evidence for chromosome 19 linkage

1 reference

12 December 2020

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1 reference

12 December 2020

Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme

1 reference

12 December 2020

The transcriptional factor LBP-1c/CP2/LSF gene on chromosome 12 is a genetic determinant of Alzheimer's disease.

1 reference

12 December 2020

Genetic polymorphism of cathepsin D is strongly associated with the risk for developing sporadic Alzheimer's disease.

1 reference

12 December 2020

A genetic variation of cathepsin D is a major risk factor for Alzheimer's disease.

1 reference

12 December 2020

The alpha2-macroglobulin gene in AD: a population-based study and meta-analysis

1 reference

12 December 2020

Candidate genes showing no evidence for association or linkage with Alzheimer's disease using family-based methodologies.

1 reference

12 December 2020

Susceptibility locus for Alzheimer's disease on chromosome 10.

1 reference

12 December 2020

Evidence against association of the FE65 gene (APBB1) intron 13 polymorphism in Alzheimer's patients

1 reference

12 December 2020

Predicting the range of linkage disequilibrium

1 reference

12 December 2020

Accounting for unmeasured population substructure in case-control studies of genetic association using a novel latent-class model

1 reference

12 December 2020

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

1 reference

12 December 2020

Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12.

1 reference

12 December 2020

Evidence for genetic linkage of Alzheimer's disease to chromosome 10q

1 reference

12 December 2020

The presenilins in Alzheimer's disease--proteolysis holds the key.

1 reference

12 December 2020

Alpha2-macroglobulin gene and Alzheimer's disease: confirmation of association by haplotypes analyses.

1 reference

12 December 2020

Alpha-2 macroglobulin is genetically associated with Alzheimer disease.

1 reference

12 December 2020

A genome survey for novel Alzheimer disease risk loci: results at 10-cM resolution.

1 reference

12 December 2020

Variation is the spice of life

1 reference

12 December 2020

The future of genetic studies of complex human diseases

1 reference

12 December 2020

The human FE65 gene: genomic structure and an intronic biallelic polymorphism associated with sporadic dementia of the Alzheimer type

1 reference

12 December 2020

Association of alpha-2-macroglobulin deletion polymorphism with sporadic Alzheimer's disease in Koreans.

1 reference

12 December 2020

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

1 reference

12 December 2020

Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14.

1 reference

12 December 2020

Cathepsin D gene exon 2 polymorphism and sporadic Alzheimer's disease.

1 reference

12 December 2020

The gene defects responsible for familial Alzheimer's disease

1 reference

12 December 2020

Genetic analysis of case/control data using estimated haplotype frequencies: application to APOE locus variation and Alzheimer's disease

1 reference

12 December 2020

Genetic polymorphisms in the cathespin D and interleukin-6 genes and the risk of Alzheimer's disease.

1 reference

12 December 2020

The deletion polymorphism and Val1000Ile in alpha-2-macroglobulin and Alzheimer disease in Caribbean Hispanics

1 reference

12 December 2020

A locus for familial early-onset Alzheimer's disease on the long arm of chromosome 14, proximal to the alpha 1-antichymotrypsin gene.

1 reference

12 December 2020

Apolipoprotein E and Alzheimer's disease. A role in amyloid catabolism

1 reference

12 December 2020

Linkage of plasma Abeta42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees

1 reference

12 December 2020

Non-replication of association between cathepsin D genotype and late onset Alzheimer disease

1 reference

12 December 2020

Pronounced impact of Th1/E47cs mutation compared with -491 AT mutation on neural APOE gene expression and risk of developing Alzheimer's disease.

1 reference

12 December 2020

The number of trait loci in late-onset Alzheimer disease

1 reference

12 December 2020

A full genome scan for late onset Alzheimer's disease.

1 reference

12 December 2020

APOE genotype predicts when--not whether--one is predisposed to develop Alzheimer disease.

1 reference

12 December 2020

Mapping of a gene predisposing to early-onset Alzheimer's disease to chromosome 14q24.3

1 reference

12 December 2020

Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14

1 reference

12 December 2020

ApoE genotype and familial Alzheimer's disease: a possible influence on age of onset in APP717 Val-->Ile mutated families.

1 reference

12 December 2020

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

1 reference

12 December 2020

No evidence for genetic association or linkage of the cathepsin D (CTSD) exon 2 polymorphism and Alzheimer disease.

1 reference

12 December 2020

Candidate gene for the chromosome 1 familial Alzheimer's disease locus

1 reference

12 December 2020

Genetic association of alpha2-macroglobulin with Alzheimer's disease in a Finnish elderly population

1 reference

12 December 2020

10.1007/S11910-001-0104-9

Identifiers

DOI

1 reference

PubMed ID

11898555

Dimensions Publication ID

3 August 2017

0 references

1 reference

PubMed ID

11898555