(Q34570298)

English

Downregulation of the male-specific hepatic microsomal steroid 16 alpha-hydroxylase, cytochrome P-450UT-A, in rats with portal bypass. Relevance to estradiol accumulation and impaired drug metabolism in hepatic cirrhosis

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Downregulation of the male-specific hepatic microsomal steroid 16 alpha-hydroxylase, cytochrome P-450UT-A, in rats with portal bypass. Relevance to estradiol accumulation and impaired drug metabolism in hepatic cirrhosis (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

liver cirrhosis

0 references

author name string

E Cantrill

1

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

M Murray

2

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

I Mehta

3

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

G C Farrell

4

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

language of work or name

0 references

publication date

1 April 1989

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Journal of Clinical Investigation

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

83

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

1211-1216

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Protein measurement with the Folin phenol reagent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303809

7 July 2018

Radiometric analysis of biological oxidations in man: sex differences in estradiol metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303809

7 July 2018

Metabolism of progesterone and estradiol by microsomes and purified cytochrome P-450 RLM3 and RLM5

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303809

7 July 2018

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303809

7 July 2018

Neonatal imprinting of liver microsomal hydroxylation and reduction of steroids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303809

7 July 2018

Pharmacological implications of microsomal enzyme induction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303809

7 July 2018

Regulation of rat hepatic cytochrome P-450: age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex-specific isoenzymes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303809

7 July 2018

Liver disease and the hypothalamic pituitary gonadal axis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303809

7 July 2018

Effects of portal vein ligation on sex hormone metabolism in male rats: relationship to lowered hepatic cytochrome P450 levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303809

7 July 2018

Drug metabolism in cirrhosis. Selective changes in cytochrome P-450 isozymes in the choline-deficient rat model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303809

7 July 2018

17 beta-estradiol 2- and 4-hydroxylation catalyzed by rat hepatic cytochrome P-450: roles of individual forms, inductive effects, developmental patterns, and alterations by gonadectomy and hormone replacement.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303809

7 July 2018

Source of raised serum estrogens in male rats with portal bypass

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303809

7 July 2018

Interactions of hepatic cytochromes P-450 with steroid hormones. Regioselectivity and stereospecificity of steroid metabolism and hormonal regulation of rat P-450 enzyme expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303809

7 July 2018

Monoclonal antibodies inhibitory to rat hepatic cytochromes P-450: P-450 form specificities and use as probes for cytochrome P-450-dependent steroid hydroxylations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303809

7 July 2018

Microsomal 17beta-hydroxysteroid dehydrogenase of guinea pig liver: detergent solubilization and a comparison of kinetic and stability properties of bound and solubilized forms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303809

7 July 2018

Serum somatomedin activity measured as sulphation factor in peripheral, hepatic and renal veins of patients with alcoholic cirrhosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303809

7 July 2018

Evidence for a Defect in Pituitary Secretion of Luteinizing Hormone in Chronic Alcoholic Men*

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303809

7 July 2018

Isolation and purification of cytochrome P-450, and the existence of multiple forms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303809

7 July 2018

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303809

7 July 2018

Thyrotropin-releasing hormone (TRH)-induced growth hormone (hGH) responses in cirrhotic men

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303809

7 July 2018

Alkaline phosphatase and peroxidase for double immunoenzymatic labelling of cellular constituents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303809

7 July 2018

Species, sex, and developmental differences in the O- and N-dealkylation of ethylmorphine by hepatic microsomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303809

7 July 2018

Rat hepatic cytochrome P-450 isoenzyme 2c. Identification as a male-specific, developmentally induced steroid 16 alpha-hydroxylase and comparison to a female-specific cytochrome P-450 isoenzyme.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303809

27 October 2018

Regioselectivity and stereoselectivity of androgen hydroxylations catalyzed by cytochrome P-450 isozymes purified from phenobarbital-induced rat liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303809

9 December 2018

Hormonal regulation of rat liver microsomal enzymes. Role of gonadal steroids in programming, maintenance, and suppression of delta 4-steroid 5 alpha-reductase, flavin-containing monooxygenase, and sex-specific cytochromes P-450

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303809

9 December 2018

Selective reactivation of steroid hydroxylases following dissociation of the isosafrole metabolite complex with rat hepatic cytochrome P-450

1 reference

https://pubmed.ncbi.nlm.nih.gov/2703529

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sex difference in rate of ring A reduction of delta 4-3-keto-steroids in vitro by rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/2703529

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired androgen 16 alpha-hydroxylation in hepatic microsomes from carbon tetrachloride-cirrhotic male rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/2703529

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of levels of phenobarbital-inducible rat liver cytochrome P-450 by pituitary hormone

1 reference

https://pubmed.ncbi.nlm.nih.gov/2703529

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic clearance of human growth hormone in patients with hepatic and renal failure, and in the isolated perfused pig liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/2703529

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced serum somatomedin activity in patients with chronic liver disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/2703529

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic functional deterioration after portacaval shunt in the rat. Effects on sulfobromophthalein transport-maximum, indocyanine green clearance and galactose elimination capacity

1 reference

https://pubmed.ncbi.nlm.nih.gov/2703529

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aromatization of androstenedione by human adult liver in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/2703529

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between plasma level of growth hormone and sex differentiation of hepatic steroid metabolism in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/2703529

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterization of liver microsomal cytochromes p-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or beta-naphthoflavone

1 reference

https://pubmed.ncbi.nlm.nih.gov/2703529

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Portal vein ligation selectively lowers hepatic cytochrome P450 levels in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/2703529

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regio- and stereoselective metabolism of two C19 steroids by five highly purified and reconstituted rat hepatic cytochrome P-450 isozymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2703529

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sex difference of cytochrome P-450 in the rat: purification, characterization, and quantitation of constitutive forms of cytochrome P-450 from liver microsomes of male and female rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/2703529

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hormonal and developmental regulation of expression of the hepatic microsomal steroid 16 alpha-hydroxylase cytochrome P-450 apoprotein in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/2703529

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

17 beta-Hydroxysteroid oxidoreductase: a ubiquitous enzyme. Interconversion of estrone and estradiol-17 beta in BALB/c mouse tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/2703529

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Normal and recombinant human growth hormone administered by constant infusion feminize catechol estrogen formation by rat liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2703529

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic microsomal metabolism of androst-4-ene-3,17-dione: relative importance of ring hydroxylation and aromatization in control and induced rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/2703529

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complexation of cytochrome P-450 isozymes in hepatic microsomes from SKF 525-A-induced rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/2703529

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered regulation of cytochrome P-450 enzymes in choline-deficient cirrhotic male rat liver: impaired regulation and activity of the male-specific androst-4-ene-3,17-dione 16 alpha-hydroxylase, cytochrome P-450UT-A, in hepatic cirrhosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/2703529

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI114003

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

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