(Q34573852)

3 August 2017

title

Novel pycnodysostosis mouse model uncovers cathepsin K function as a potential regulator of osteoclast apoptosis and senescence (English)

1 reference

3 August 2017

0 references

Wei Chen

1

1 reference

3 August 2017

Shuying Yang

2

1 reference

3 August 2017

Yoke Abe

3

1 reference

3 August 2017

Ming Li

4

1 reference

3 August 2017

Yucheng Wang

5

1 reference

3 August 2017

Jianzhong Shao

6

1 reference

3 August 2017

En Li

7

1 reference

3 August 2017

Yi-Ping Li

8

1 reference

3 August 2017

publication date

8 January 2007

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3 August 2017

published in

Human Molecular Genetics

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3 August 2017

volume

16

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3 August 2017

issue

4

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3 August 2017

page(s)

410-423

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Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation.

3 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

The signals and pathways activating cellular senescence

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

Cathepsin K: a cysteine protease with unique kinin-degrading properties

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

Decreased bone turnover and deterioration of bone structure in two cases of pycnodysostosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

Regulation of the formation of osteoclastic actin rings by proline-rich tyrosine kinase 2 interacting with gelsolin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

Expression of cathepsins B, H, K, L, and S during human fetal lung development

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

Pycnodysostosis: role and regulation of cathepsin K in osteoclast function and human disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

Mitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

Linking osteopetrosis and pycnodysostosis: regulation of cathepsin K expression by the microphthalmia transcription factor family

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

JunD protects cells from p53-dependent senescence and apoptosis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

Generation of mouse osteoclastogenic cell lines immortalized with SV40 large T antigen

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

A nonsense mutation in the cathepsin K gene observed in a family with pycnodysostosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

Cloning and complete coding sequence of a novel human cathepsin expressed in giant cells of osteoclastomas

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

Animal models of human genetic diseases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

Characterization of a tumor necrosis factor-responsive element which down-regulates the human osteocalcin gene

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

Molecular cloning of a possible cysteine proteinase predominantly expressed in osteoclasts.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

Molecular cloning of human cDNA for cathepsin K: novel cysteine proteinase predominantly expressed in bone

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

Molecular cloning of human cathepsin O, a novel endoproteinase and homologue of rabbit OC2

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

Human cathepsin O2, a novel cysteine protease highly expressed in osteoclastomas and ovary molecular cloning, sequencing and tissue distribution

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

Simplified mammalian DNA isolation procedure

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578583

Pyknodysostosis: visceral manifestations and simian crease

7 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL474

Atp6i-deficient mice exhibit severe osteopetrosis due to loss of osteoclast-mediated extracellular acidification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL474

NFATc1 expression in the developing heart valves is responsive to the RANKL pathway and is required for endocardial expression of cathepsin K.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL474

Cathepsin K Knockout Mice Develop Osteopetrosis Due to a Deficit in Matrix Degradation but Not Demineralization

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL474

Mice lacking cathepsin K maintain bone remodeling but develop bone fragility despite high bone mass.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL474

Reciprocal role of ERK and NF-kappaB pathways in survival and activation of osteoclasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL474

Post-natal lethality and neurological and gastrointestinal defects in mice with targeted disruption of the A-Raf protein kinase gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL474

Linkage of M-CSF signaling to Mitf, TFE3, and the osteoclast defect in Mitf(mi/mi) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL474

Healing of alveolar bone in resorbable and non-resorbable membrane-protected defects. A histologic pilot study in dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL474

Detection and characterization of apoptosis in osteoclasts in vitro

21 January 2018

1 reference

12 December 2020

Functional heterogeneity of osteoclasts: matrix metalloproteinases participate in osteoclastic resorption of calvarial bone but not in resorption of long bone

1 reference

12 December 2020

Phagocytosis of bone collagen by osteoclasts in two cases of pycnodysostosis

1 reference

12 December 2020

Mutations of CTSK result in pycnodysostosis via a reduction in cathepsin K protein

1 reference

12 December 2020

Impaired bone resorption in cathepsin K-deficient mice is partially compensated for by enhanced osteoclastogenesis and increased expression of other proteases via an increased RANKL/OPG ratio

1 reference

12 December 2020

Pycnodysostosis. Orthopedic aspects with a description of 14 new cases

1 reference

12 December 2020

Genetics and bone. Using the mouse to understand man

1 reference

12 December 2020

Identifiers

DOI

10.1093/HMG/DDL474

1 reference

3 August 2017

1 reference

3 August 2017

1 reference