(Q34580749)

3 August 2017

title

Neuroprotective and anticonvulsant effects of EGIS-8332, a non-competitive AMPA receptor antagonist, in a range of animal models (English)

1 reference

3 August 2017

G Gigler

1

1 reference

3 August 2017

K Móricz

2

1 reference

3 August 2017

M Agoston

3

1 reference

3 August 2017

A Simó

4

1 reference

3 August 2017

M Albert

5

1 reference

3 August 2017

A Benedek

6

1 reference

3 August 2017

G Kapus

7

1 reference

3 August 2017

S Kertész

8

1 reference

3 August 2017

M Vegh

9

1 reference

3 August 2017

J Barkóczy

10

1 reference

3 August 2017

B Markó

11

1 reference

3 August 2017

G Szabó

12

1 reference

3 August 2017

E Matucz

13

1 reference

3 August 2017

I Gacsályi

14

1 reference

3 August 2017

G Lévay

15

1 reference

3 August 2017

L G Hársing

16

1 reference

3 August 2017

G Szénási

17

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3 August 2017

language of work or name

English

0 references

publication date

2 July 2007

1 reference

British Journal of Pharmacology

3 August 2017

published in

1 reference

3 August 2017

volume

152

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3 August 2017

issue

1

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3 August 2017

page(s)

151-160

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NXY-059 for acute ischemic stroke

3 August 2017

cites work

1 reference

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7 July 2018

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Isoflurane preconditioning decreases glutamate receptor overactivation-induced Purkinje neuronal injury in rat cerebellar slices

7 July 2018

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The AMPA-antagonist talampanel is neuroprotective in rodent models of focal cerebral ischemia

7 July 2018

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7 July 2018

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AMPA receptor antagonists for the treatment of stroke

7 July 2018

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AMPA receptor blockade potentiates the stimulatory effect of L-DOPA on dopamine release in dopamine-deficient corticostriatal slice preparation

7 July 2018

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AMPA receptor-mediated neurotoxicity: role of Ca2+ and desensitization

7 July 2018

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Comparative assays of antiepileptic drugs in mice and rats

7 July 2018

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Hypothermia rescues hippocampal CA1 neurons and attenuates down-regulation of the AMPA receptor GluR2 subunit after forebrain ischemia

7 July 2018

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Isoflurane decreases AMPA-induced dark cell degeneration and edematous damage of Purkinje neurons in the rat cerebellar slices

7 July 2018

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AMPA receptor antagonists with additional mechanisms of action: new opportunities for neuroprotective drugs?

7 July 2018

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AMPA receptor antagonists

7 July 2018

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Influence of LY 300164, an antagonist of AMPA/kainate receptors, on the anticonvulsant activity of clonazepam

7 July 2018

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The glutamate receptor ion channels

7 July 2018

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ZK200775: a phosphonate quinoxalinedione AMPA antagonist for neuroprotection in stroke and trauma

7 July 2018

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Neuroprotective effect of YM90K, an AMPA-receptor antagonist, against delayed neuronal death induced by transient global cerebral ischemia in gerbils and rats

7 July 2018

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AMPA neurotoxicity in cultured cerebellar granule neurons: mode of cell death.

7 July 2018

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Activity of 2,3-benzodiazepines at native rat and recombinant human glutamate receptors in vitro: stereospecificity and selectivity profiles

7 July 2018

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Effect of lactacidosis on pyridine nucleotide stability during ischemia in mouse brain

7 July 2018

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A crossover, add-on trial of talampanel in patients with refractory partial seizures

7 July 2018

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Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJP.0707362

The new 2,3-benzodiazepine derivative EGIS-8332 inhibits AMPA/kainate ion channels and cell death

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978282

Therapeutic time window of neuroprotection by non-competitive AMPA antagonists in transient and permanent focal cerebral ischemia in rats

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978282

Isoflurane exerts neuroprotective actions at or near the time of severe traumatic brain injury

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978282

Talampanel improves the functional deficit after transient focal cerebral ischemia in rats. A 30-day follow up study

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978282

The effects of AMPA receptor antagonists in models of stroke and neurodegeneration

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978282

Novel alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptor antagonists of 2,3-benzodiazepine type: chemical synthesis, in vitro characterization, and in vivo prevention of acute neurodegeneration

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978282

Reduction of cerebral infarct size by non-competitive AMPA antagonists in rats subjected to permanent and transient focal ischemia

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978282

Comparison of the AMPA antagonist action of new 2,3-benzodiazepines in vitro and their neuroprotective effects in vivo

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978282

Comparison of anticonvulsive and acute neuroprotective activity of three 2,3-benzodiazepine compounds, GYKI 52466, GYKI 53405, and GYKI 53655.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978282

The neuroprotective and hypothermic effect of GYKI-52466, a non-competitive alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-antagonist on histological and behavioural variables in the gerbil global ischemia model.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978282

SPD 502: a water-soluble and in vivo long-lasting AMPA antagonist with neuroprotective activity

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978282

GYKI 53665, a 2,3-benzodiazepine, non-competitively protects cultured neurones against AMPA toxicity

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978282

Stereoselective effects-of 2,3-benzodiazepines in vivo: electrophysiology and neuroprotection studies

27 October 2018

1 reference

12 December 2020

2,3-benzodiazepine AMPA antagonists

1 reference

12 December 2020

The anticonvulsant effect of the non-NMDA antagonists, NBQX and GYKI 52466, in mice

1 reference

12 December 2020

Anticonvulsant activity of AMPA/kainate antagonists: comparison of GYKI 52466 and NBOX in maximal electroshock and chemoconvulsant seizure models

1 reference

12 December 2020

New non competitive AMPA antagonists

1 reference

12 December 2020

Comprehensive observational assessment: Ia. A systematic, quantitative procedure for assessing the behavioral and physiologic state of the mouse

1 reference

12 December 2020

A pharmacological investigation of 2,5-bis-(3-diethylaminopropylamino) benzoquinone-bis-benzylchloride (WIN 2747): a new curarimimetic drug

1 reference

12 December 2020

A Reliable and Sensitive Method to Localize Terminal Degeneration and Lysosomes in the Central Nervous System

1 reference

12 December 2020

Focal Brain Ischemia in the Rat: Methods for Reproducible Neocortical Infarction Using Tandem Occlusion of the Distal Middle Cerebral and Ipsilateral Common Carotid Arteries

1 reference

12 December 2020

The reliability of graphic estimates of relative potency from dose-per cent effect curves

1 reference

12 December 2020

Synthesis and Anticonvulsant Activity of Novel and Potent 2,3-Benzodiazepine AMPA/Kainate Receptor Antagonists

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.BJP.0707362

1 reference

3 August 2017

1 reference

3 August 2017

1 reference