(Q34581706)

3 August 2017

1 reference

title

Factors confounding the successful extrapolation of in vitro CYP3A inhibition information to the in vivo condition (English)

1 reference

3 August 2017

Larry C Wienkers

1

1 reference

PubMed ID

11923055

3 August 2017

language of work or name

English

0 references

publication date

1 April 2002

1 reference

European Journal of Pharmaceutical Sciences

3 August 2017

1 reference

3 August 2017

15

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3 August 2017

239-242

1 reference

3 August 2017

3

1 reference

Cortisol metabolism in vitro--III. Inhibition of microsomal 6 beta-hydroxylase and cytosolic 4-ene-reductase

3 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900002-7

7 January 2021

Allosteric behavior in cytochrome p450-dependent in vitro drug-drug interactions: a prospective based on conformational dynamics

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900002-7

7 January 2021

Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900002-7

7 January 2021

Metabolism of artelinic acid to dihydroqinqhaosu by human liver cytochrome P4503A.

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900002-7

7 January 2021

Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900002-7

7 January 2021

Analysis of human cytochrome P450 3A4 cooperativity: construction and characterization of a site-directed mutant that displays hyperbolic steroid hydroxylation kinetics

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900002-7

7 January 2021

The mechanism of the interaction between amiodarone and warfarin in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900002-7

7 January 2021

Elucidation of distinct ligand binding sites for cytochrome P450 3A4

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900002-7

7 January 2021

Identification of the cytochrome P450 enzymes involved in the N-demethylation of sildenafil

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900002-7

7 January 2021

High rates of substrate hydroxylation by human cytochrome P450 3A4 in reconstituted membranous vesicles: influence of membrane charge

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900002-7

7 January 2021

Involvement of cytochrome P450 3A4 in N-dealkylation of buprenorphine in human liver microsomes

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900002-7

7 January 2021

CYP3A4 drug interactions: correlation of 10 in vitro probe substrates

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900002-7

7 January 2021

Identification of human cytochrome P450 isoforms involved in the metabolism of brotizolam

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900002-7

7 January 2021

Covalent alteration of the CYP3A4 active site: evidence for multiple substrate binding domains

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900002-7

7 January 2021

Activation of CYP3A4: evidence for the simultaneous binding of two substrates in a cytochrome P450 active site.

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900002-7

7 January 2021

In vitro and in vivo drug interactions involving human CYP3A.

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900002-7

7 January 2021

Cooperativity in oxidations catalyzed by cytochrome P450 3A4.

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900002-7

7 January 2021

Inhibition of terfenadine metabolism in vitro by azole antifungal agents and by selective serotonin reuptake inhibitor antidepressants: relation to pharmacokinetic interactions in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900002-7

7 January 2021

Lack of electron transfer from cytochrome b5 in stimulation of catalytic activities of cytochrome P450 3A4. Characterization of a reconstituted cytochrome P450 3A4/NADPH-cytochrome P450 reductase system and studies with apo-cytochrome b5.

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2802%2900002-7

7 January 2021

10.1016/S0928-0987(02)00002-7

Identifiers

DOI

1 reference

3 August 2017

1 reference

PubMed ID

11923055