(Q34583556)

English

Critical role of the STAT3 pathway in the cardioprotective efficacy of zoniporide in a model of myocardial preservation - the rat isolated working heart

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

Critical role of the STAT3 pathway in the cardioprotective efficacy of zoniporide in a model of myocardial preservation - the rat isolated working heart (English)

1 reference

Europe PubMed Central

3 August 2017

author name string

L Gao

1

1 reference

Europe PubMed Central

3 August 2017

J Tsun

2

1 reference

Europe PubMed Central

3 August 2017

L Sun

3

1 reference

Europe PubMed Central

3 August 2017

J Kwan

4

1 reference

Europe PubMed Central

3 August 2017

A Watson

5

1 reference

Europe PubMed Central

3 August 2017

P S Macdonald

6

1 reference

Europe PubMed Central

3 August 2017

M Hicks

7

1 reference

Europe PubMed Central

3 August 2017

language of work or name

0 references

publication date

1 February 2011

1 reference

Europe PubMed Central

3 August 2017

British Journal of Pharmacology

1 reference

Europe PubMed Central

3 August 2017

162

1 reference

Europe PubMed Central

3 August 2017

3

1 reference

Europe PubMed Central

3 August 2017

633-647

1 reference

Europe PubMed Central

3 August 2017

MicroRNA-21 is a key determinant in IL-11/Stat3 anti-apoptotic signalling pathway in preconditioning of skeletal myoblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

7 July 2018

Targeting for cardioplegia: arresting agents and their safety

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

7 July 2018

Activation of the protective Survivor Activating Factor Enhancement (SAFE) pathway against reperfusion injury: Does it go beyond the RISK pathway?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

7 July 2018

Regulating RISK: a role for JAK-STAT signaling in postconditioning?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

7 July 2018

Signal transducer and activator of transcription 3 is involved in the cardioprotective signalling pathway activated by insulin therapy at reperfusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

7 July 2018

Insulin-like growth factor-I protects cells from ER stress-induced apoptosis via enhancement of the adaptive capacity of endoplasmic reticulum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

7 July 2018

Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

7 July 2018

Sodium-hydrogen exchange inhibition by cariporide to reduce the risk of ischemic cardiac events in patients undergoing coronary artery bypass grafting: results of the EXPEDITION study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

7 July 2018

Sodium/hydrogen exchange inhibition with cariporide reduces leukocyte adhesion via P-selectin suppression during inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

7 July 2018

The Na+/H+ exchanger, NHE1, differentially regulates mitogen-activated protein kinase subfamilies after osmotic shrinkage in Ehrlich Lettre Ascites cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

7 July 2018

Preconditioning and postconditioning: united at reperfusion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

7 July 2018

Roles of Na+/H+ exchange in regulation of p38 mitogen-activated protein kinase activity and cell death after chemical anoxia in NIH3T3 fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

7 July 2018

Regulation of mitogen-activated protein kinase pathways by the plasma membrane Na+/H+ exchanger, NHE1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

7 July 2018

Stattic: a small-molecule inhibitor of STAT3 activation and dimerization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

7 July 2018

The JAK/STAT pathway is essential for opioid-induced cardioprotection: JAK2 as a mediator of STAT3, Akt, and GSK-3 beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

7 July 2018

A novel platinum compound inhibits constitutive Stat3 signaling and induces cell cycle arrest and apoptosis of malignant cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

7 July 2018

The NHE1 Na+/H+ exchanger recruits ezrin/radixin/moesin proteins to regulate Akt-dependent cell survival.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

7 July 2018

Cardioprotective efficacy of zoniporide, a potent and selective inhibitor of Na+/H+ exchanger isoform 1, in an experimental model of cardiopulmonary bypass

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

7 July 2018

Cariporide (HOE642), a Selective Na + -H + Exchange Inhibitor, Inhibits the Mitochondrial Death Pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

7 July 2018

Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

7 July 2018

Zoniporide: a potent and selective inhibitor of the human sodium-hydrogen exchanger isoform 1 (NHE-1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

7 July 2018

Na(+)/H(+) exchange inhibitors for cardioprotective therapy: progress, problems and prospects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

7 July 2018

An essential role of the JAK-STAT pathway in ischemic preconditioning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

7 July 2018

The role of the myocardial sodium-hydrogen exchanger in mediating ischemic and reperfusion injury. From amiloride to cariporide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

7 July 2018

B-Raf inhibits programmed cell death downstream of cytochrome c release from mitochondria by activating the MEK/Erk pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

7 July 2018

Platelet-derived growth factor induces phosphorylation of multiple JAK family kinases and STAT proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

7 July 2018

A rapid ischemia-induced apoptosis in isolated rat hearts and its attenuation by the sodium-hydrogen exchange inhibitor HOE 642 (cariporide).

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01071.X

21 January 2018

Synthesis and in vitro evaluation of sulfonamide isatin Michael acceptors as small molecule inhibitors of caspase-6.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01071.X

21 January 2018

Dexamethasone-induced cardioprotection: a role for the phosphatase MKP-1?

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01071.X

21 January 2018

Kinases and phosphatases in ischaemic preconditioning: a re-evaluation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01071.X

21 January 2018

Improved preservation of the rat heart with celsior solution supplemented with cariporide plus glyceryl trinitrate

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01071.X

21 January 2018

Na+/H+ exchanger-1 inhibitors decrease myocardial superoxide production via direct mitochondrial action

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01071.X

21 January 2018

Role of STAT3 in ischemic preconditioning

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01071.X

21 January 2018

Combining cariporide with glyceryl trinitrate optimizes cardiac preservation during porcine heart transplantation.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01071.X

21 January 2018

NHE-1 inhibition-induced cardioprotection against ischaemia/reperfusion is associated with attenuation of the mitochondrial permeability transition

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01071.X

21 January 2018

Ischaemic postconditioning protects against reperfusion injury via the SAFE pathway

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01071.X

21 January 2018

Zoniporide: a potent and highly selective inhibitor of human Na(+)/H(+) exchanger-1.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01071.X

21 January 2018

Mitochondrial ATP-sensitive K+ channels play a role in cardioprotection by Na+-H+ exchange inhibition against ischemia/reperfusion injury

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01071.X

21 January 2018

Novel functional interaction between Na+/H+ exchanger 1 and tyrosine phosphatase SHP-2.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01071.X

21 January 2018

Evidence that cardioprotection by postconditioning involves preservation of myocardial opioid content and selective opioid receptor activation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01071.X

21 January 2018

Postconditioning reduces infarct size and cardiac myocyte apoptosis via the opioid receptor and JAK-STAT signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

27 October 2018

Guide to Receptors and Channels (GRAC), 4th Edition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

27 October 2018

A novel sodium-hydrogen exchanger isoform-1 inhibitor, zoniporide, reduces ischemic myocardial injury in vitro and in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041253

27 October 2018

Effects of the Na+/H+ exchange inhibitor cariporide (HOE 642) on cardiac function and cardiomyocyte cell death in rat ischaemic-reperfused heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/20942815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Na(+)/H(+) exchange inhibition with HOE642 improves postischemic recovery due to attenuation of Ca(2+) overload and prolonged acidosis on reperfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20942815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardioprotective effects of the Na(+)/H(+) exchange inhibitor cariporide in patients with acute anterior myocardial infarction undergoing direct PTCA

1 reference

https://pubmed.ncbi.nlm.nih.gov/20942815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of JAK/STAT pathway transduces cytoprotective signal in rat acute myocardial infarction

1 reference

https://pubmed.ncbi.nlm.nih.gov/20942815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Na(+)/H(+) exchange inhibitor cariporide attenuates cell injury predominantly during ischemia and not at onset of reperfusion in porcine hearts with low residual blood flow

1 reference

https://pubmed.ncbi.nlm.nih.gov/20942815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the sodium-hydrogen exchanger with cariporide to prevent myocardial infarction in high-risk ischemic situations. Main results of the GUARDIAN trial. Guard during ischemia against necrosis (GUARDIAN) Investigators

1 reference

https://pubmed.ncbi.nlm.nih.gov/20942815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Na+/H+ exchange in ischemia, reperfusion and preconditioning

1 reference

https://pubmed.ncbi.nlm.nih.gov/20942815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantification of histochemical staining by color deconvolution

1 reference

https://pubmed.ncbi.nlm.nih.gov/20942815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Emerging role of the JAK-STAT pathway as a mechanism of protection against ischemia/reperfusion injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/20942815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardioprotection by cariporide after prolonged hypothermic storage of the isolated working rat heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/20942815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

STAT-3 activation is necessary for ischemic preconditioning in hypertrophied myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/20942815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Organ preservation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20942815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new small-molecule Stat3 inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20942815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardioprotection by ischemic postconditioning is lost in aged and STAT3-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20942815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardio-protective signalling by glyceryl trinitrate and cariporide in a model of donor heart preservation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20942815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amiloride enhances postischemic ventricular recovery: possible role of Na+-H+ exchange

1 reference

https://pubmed.ncbi.nlm.nih.gov/20942815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experimental evaluation of Celsior, a new heart preservation solution

1 reference

https://pubmed.ncbi.nlm.nih.gov/20942815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Na+/H+ exchanger inhibitor HOE-642 improves cardioplegic myocardial preservation under both normothermic and hypothermic conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/20942815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sodium/hydrogen exchanger inhibition reduces myocardial reperfusion edema after normothermic cardioplegia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20942815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1476-5381.2010.01071.X

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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