(Q34583868)

3 August 2017

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title

Unraveling the complexities of the Raf/MAP kinase pathway for pharmacological intervention (English)

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3 August 2017

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Roman Herrera

1

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3 August 2017

Judith S Sebolt-Leopold

series ordinal

2

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3 August 2017

publication date

1 January 2002

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Trends in Molecular Medicine

3 August 2017

published in

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3 August 2017

volume

8

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3 August 2017

issue

4 Suppl

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3 August 2017

page(s)

S27-31

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3 August 2017

cites work

The Hallmarks of Cancer

1 reference

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7 January 2021

The Raf signal transduction cascade as a target for chemotherapeutic intervention in growth factor-responsive tumors

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7 January 2021

Signaling from Ras to Rac and beyond: not just a matter of GEFs

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7 January 2021

Both farnesyltransferase and geranylgeranyltransferase I inhibitors are required for inhibition of oncogenic K-Ras prenylation but each alone is sufficient to suppress human tumor growth in nude mouse xenografts

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7 January 2021

Farnesyltransferase inhibitors: mechanism and applications

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7 January 2021

Current status of clinical trials of farnesyltransferase inhibitors.

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7 January 2021

Clinical and biologic activity of the farnesyltransferase inhibitor R115777 in adults with refractory and relapsed acute leukemias: a phase 1 clinical-laboratory correlative trial

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7 January 2021

Evolving therapies: farnesyltransferase inhibitors

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7 January 2021

Absence of the CAAX endoprotease Rce1: effects on cell growth and transformation

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902307-9

7 January 2021

Discovery of a novel Raf kinase inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902307-9

7 January 2021

Drugs targeted against protein kinases

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7 January 2021

Abrogation of c-Raf expression induces apoptosis in tumor cells.

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7 January 2021

Endothelial apoptosis in Braf-deficient mice

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7 January 2021

Raf-1 promotes cell survival by antagonizing apoptosis signal-regulating kinase 1 through a MEK-ERK independent mechanism

1 reference

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7 January 2021

Rsk1 mediates a MEK-MAP kinase cell survival signal

1 reference

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7 January 2021

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

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7 January 2021

Independent control of cell survival by Raf-1 and Bcl-2 at the mitochondria

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7 January 2021

Uncoupling Raf1 from MEK1/2 impairs only a subset of cellular responses to Raf activation

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7 January 2021

Raf induces NF-kappaB by membrane shuttle kinase MEKK1, a signaling pathway critical for transformation

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7 January 2021

Phosphorylation and regulation of Raf by Akt (protein kinase B)

1 reference

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7 January 2021

Serum- and glucocorticoid-inducible kinase SGK phosphorylates and negatively regulates B-Raf

1 reference

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7 January 2021

Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902307-9

7 January 2021

Biomarker assays for phosphorylated MAP kinase. Their utility for measurement of MEK inhibition

1 reference

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7 January 2021

Measurement of MAP kinase activation by flow cytometry using phospho-specific antibodies to MEK and ERK: potential for pharmacodynamic monitoring of signal transduction inhibitors.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902307-9

7 January 2021

10.1016/S1471-4914(02)02307-9

Identifiers

DOI

1 reference

release_owyhyktnffe2dkl3ohz3ong3je

3 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/owyhyktnffe2dkl3ohz3ong3je

24 November 2022

mapped directly with Wikidata item

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