(Q34592214)

3 August 2017

title

From gene to behavior and back again: new perspectives on GABAA receptor subunit selectivity of alcohol actions (English)

1 reference

3 August 2017

Stephen L Boehm

1

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3 August 2017

Igor Ponomarev

series ordinal

2

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3 August 2017

Yuri A Blednov

series ordinal

3

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3 August 2017

R Adron Harris

series ordinal

4

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3 August 2017

publication date

1 January 2006

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3 August 2017

published in

Advances in Pharmacology

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3 August 2017

volume

54

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3 August 2017

page(s)

171-203

1 reference

Chromosomal loci influencing chronic alcohol withdrawal severity

3 August 2017

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Deletion of the alpha1 or beta2 subunit of GABAA receptors reduces actions of alcohol and other drugs

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gamma-Aminobutyric acid A receptor subunit mutant mice: new perspectives on alcohol actions

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7 January 2021

Intact sorting, targeting, and clustering of gamma-aminobutyric acid A receptor subtypes in hippocampal neurons in vitro

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7 January 2021

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Quantitative trait loci involved in genetic predisposition to acute alcohol withdrawal in mice.

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7 January 2021

Tonic inhibition in mouse hippocampal CA1 pyramidal neurons is mediated by alpha5 subunit-containing gamma-aminobutyric acid type A receptors

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7 January 2021

AA and ANA rats exhibit the R100Q mutation in the GABAA receptor alpha 6 subunit

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7 January 2021

GABAA receptor gamma 2 subunit knockdown mice have enhanced anxiety-like behavior but unaltered hypnotic response to benzodiazepines.

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7 January 2021

Genetic correlates of gene expression in recombinant inbred strains: a relational model system to explore neurobehavioral phenotypes

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7 January 2021

Enhanced learning and memory and altered GABAergic synaptic transmission in mice lacking the alpha 5 subunit of the GABAA receptor.

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7 January 2021

Abolition of zolpidem sensitivity in mice with a point mutation in the GABAA receptor gamma2 subunit.

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7 January 2021

Alcohol and genetics: new models

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7 January 2021

Identifying genes for alcohol and drug sensitivity: recent progress and future directions

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7 January 2021

Trace fear conditioning involves hippocampal alpha5 GABA(A) receptors

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7 January 2021

Deficiency of the beta 3 subunit of the type A gamma-aminobutyric acid receptor causes cleft palate in mice.

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7 January 2021

Localization of genes influencing ethanol-induced conditioned place preference and locomotor activity in BXD recombinant inbred mice.

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7 January 2021

Mice lacking the beta3 subunit of the GABAA receptor have the epilepsy phenotype and many of the behavioral characteristics of Angelman syndrome.

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7 January 2021

Identification of an acute ethanol response quantitative trait locus on mouse chromosome 2

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7 January 2021

Differences in agonist/antagonist binding affinity and receptor transduction using recombinant human gamma-aminobutyric acid type A receptors.

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7 January 2021

Postsynaptic clustering of major GABAA receptor subtypes requires the gamma 2 subunit and gephyrin

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7 January 2021

Independent assembly and subcellular targeting of GABA(A)-receptor subtypes demonstrated in mouse hippocampal and olfactory neurons in vivo

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7 January 2021

Prolongation of hippocampal miniature inhibitory postsynaptic currents in mice lacking the GABA(A) receptor alpha1 subunit

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7 January 2021

Benzodiazepine-insensitive mice generated by targeted disruption of the gamma 2 subunit gene of gamma-aminobutyric acid type A receptors

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7 January 2021

Immunocytochemical localization of gamma 2 short and gamma 2 long subunits of the GABAA receptor in the rat brain

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7 January 2021

The GABA(A) receptor alpha1 subtype in the ventral pallidum regulates alcohol-seeking behaviors.

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7 January 2021

Impaired dendritic spine maturation in GABAA receptor alpha1 subunit knock out mice

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7 January 2021

Mice devoid of gamma-aminobutyrate type A receptor beta3 subunit have epilepsy, cleft palate, and hypersensitive behavior

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7 January 2021

Gene knockout of the alpha6 subunit of the gamma-aminobutyric acid type A receptor: lack of effect on responses to ethanol, pentobarbital, and general anesthetics.

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7 January 2021

Normal electrophysiological and behavioral responses to ethanol in mice lacking the long splice variant of the gamma2 subunit of the gamma-aminobutyrate type A receptor.

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7 January 2021

A gain-of-function mutation in the GABA receptor produces synaptic and behavioral abnormalities in the mouse

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7 January 2021

Ligand-gated ion channel subunit partnerships: GABAA receptor alpha6 subunit gene inactivation inhibits delta subunit expression.

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7 January 2021

GABA(A) receptors containing (alpha)5 subunits in the CA1 and CA3 hippocampal fields regulate ethanol-motivated behaviors: an extended ethanol reward circuitry.

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7 January 2021

Functional and structural analysis of the GABAA receptor alpha 1 subunit during channel gating and alcohol modulation

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7 January 2021

General anesthetic actions in vivo strongly attenuated by a point mutation in the GABA(A) receptor beta3 subunit.

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7 January 2021

GABAA receptor beta 1, beta 2, and beta 3 subunits: comparisons in DBA/2J and C57BL/6J mice

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7 January 2021

The alpha 1 and alpha 6 subunits can coexist in the same cerebellar GABAA receptor maintaining their individual benzodiazepine-binding specificities.

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7 January 2021

Quantitative trait loci affecting initial sensitivity and acute functional tolerance to ethanol-induced ataxia and brain cAMP signaling in BXD recombinant inbred mice

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7 January 2021

Oxytocin regulates neurosteroid modulation of GABA(A) receptors in supraoptic nucleus around parturition.

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7 January 2021

Benzodiazepine-induced motor impairment linked to point mutation in cerebellar GABAA receptor.

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7 January 2021

Drug interactions at GABA(A) receptors

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7 January 2021

Altered receptor subtypes in the forebrain of GABA(A) receptor delta subunit-deficient mice: recruitment of gamma 2 subunits.

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7 January 2021

Molecular and pharmacological characterization of GABA(A) receptor alpha1 subunit knockout mice

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7 January 2021

Deletion of GABAA receptor alpha 1 subunit-containing receptors alters responses to ethanol and other anesthetics.

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7 January 2021

Genetic essential tremor in gamma-aminobutyric acidA receptor alpha1 subunit knockout mice.

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7 January 2021

A deficit of functional GABA(A) receptors in neurons of beta 3 subunit knockout mice

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7 January 2021

The distribution of thirteen GABAA receptor subunit mRNAs in the rat brain. III. Embryonic and postnatal development

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7 January 2021

Altered pharmacology of synaptic and extrasynaptic GABAA receptors on CA1 hippocampal neurons is consistent with subunit changes in a model of alcohol withdrawal and dependence

1 reference

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7 January 2021

Molecular and neuronal substrate for the selective attenuation of anxiety.

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7 January 2021

Elimination of the rho1 subunit abolishes GABA(C) receptor expression and alters visual processing in the mouse retina

1 reference

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7 January 2021

A high affinity ligand for GABAA-receptor containing alpha5 subunit antagonizes ethanol's neurobehavioral effects in Long-Evans rats

1 reference

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7 January 2021

Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype.

1 reference

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7 January 2021

Attenuated sensitivity to neuroactive steroids in gamma-aminobutyrate type A receptor delta subunit knockout mice.

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7 January 2021

Segregation of different GABAA receptors to synaptic and extrasynaptic membranes of cerebellar granule cells

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7 January 2021

Alterations in the expression of GABAA receptor subunits in cerebellar granule cells after the disruption of the alpha6 subunit gene.

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7 January 2021

The GABA-A beta3 subunit mediates anaesthesia induced by etomidate

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7 January 2021

Analysis of patterned neuronal impulses and function of neuregulin

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7 January 2021

GABA(A) receptor changes in delta subunit-deficient mice: altered expression of alpha4 and gamma2 subunits in the forebrain.

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7 January 2021

In situ hybridization histochemistry reveals a diversity of GABAA receptor subunit mRNAs in neurons of the rat spinal cord and dorsal root ganglia

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7 January 2021

Localization of genes affecting alcohol drinking in mice

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7 January 2021

Genes on mouse chromosomes 2 and 9 determine variation in ethanol consumption.

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7 January 2021

Complex-trait genetics: emergence of multivariate strategies

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7 January 2021

GABA(A) receptors: immunocytochemical distribution of 13 subunits in the adult rat brain.

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7 January 2021

Transcriptional signatures of cellular plasticity in mice lacking the alpha1 subunit of GABAA receptors.

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7 January 2021

Intact synaptic GABAergic inhibition and altered neurosteroid modulation of thalamic relay neurons in mice lacking delta subunit.

1 reference

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7 January 2021

Anesthesia sensitivity in mice that lack the beta3 subunit of the gamma-aminobutyric acid type A receptor

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7 January 2021

GABA(A) receptor beta3 subunit deletion decreases alpha2/3 subunits and IPSC duration

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7 January 2021

Anxiolytic-like action of diazepam: which GABA(A) receptor subtype is involved?

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7 January 2021

GABA(A) alpha 1 subunit knock-out mice do not show a hyperlocomotor response following amphetamine or cocaine treatment

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7 January 2021

Sedation and anesthesia mediated by distinct GABA(A) receptor isoforms.

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7 January 2021

Ethanol-induced conditioned taste aversion in BXD recombinant inbred mice.

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7 January 2021

Alcohol acceptance, preference, and sensitivity in mice. II. Quantitative trait loci mapping analysis using BXD recombinant inbred strains.

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7 January 2021

Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes.

1 reference

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7 January 2021

The R100Q mutation of the GABA(A) alpha(6) receptor subunit may contribute to voluntary aversion to ethanol in the sNP rat line

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7 January 2021

The gamma 2 subunit of GABA(A) receptors is required for maintenance of receptors at mature synapses.

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7 January 2021

Discriminative stimulus effects of ethanol in mice lacking the gamma-aminobutyric acid type A receptor delta subunit

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7 January 2021

Recombinant GABAA receptor function and ethanol

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7 January 2021

Reduced inhibition and sensitivity to neurosteroids in hippocampus of mice lacking the GABA(A) receptor delta subunit

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7 January 2021

Hormonally regulated alpha(4)beta(2)delta GABA(A) receptors are a target for alcohol

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7 January 2021

Loss of the major GABA(A) receptor subtype in the brain is not lethal in mice.

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7 January 2021

Genotyping new BXD recombinant inbred mouse strains and comparison of BXD and consensus maps

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954008-6

7 January 2021

Targeted disruption of the GABA(A) receptor delta subunit gene leads to an up-regulation of gamma 2 subunit-containing receptors in cerebellar granule cells

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954008-6

7 January 2021

Homeostatic plasticity in neuronal networks: the more things change, the more they stay the same

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7 January 2021

Homeostatic plasticity in the developing nervous system

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7 January 2021

Subunit mutations affect ethanol actions on GABA(A) receptors expressed in Xenopus oocytes

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7 January 2021

Long-range interactions in neuronal gene expression: evidence from gene targeting in the GABA(A) receptor beta2-alpha6-alpha1-gamma2 subunit gene cluster

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7 January 2021

GABAA/benzodiazepine receptor alpha 6 subunit mRNA in granule cells of the cerebellar cortex and cochlear nuclei: expression in developing and mutant mice

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7 January 2021

GABA(A) receptor alpha1 subunit deletion prevents developmental changes of inhibitory synaptic currents in cerebellar neurons.

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7 January 2021

Ethanol sensitivity of the GABAA receptor expressed in xenopus oocytes requires 8 amino acids contained in the γ2L subunit

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7 January 2021

Ethanol enhances alpha 4 beta 3 delta and alpha 6 beta 3 delta gamma-aminobutyric acid type A receptors at low concentrations known to affect humans

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7 January 2021

WebQTL: web-based complex trait analysis

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7 January 2021

The α1,α2, and α3 Subunits of GABAA Receptors: Comparison in Seizure-Prone and -Resistant Mice and during Development.

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7 January 2021

Perisynaptic localization of delta subunit-containing GABA(A) receptors and their activation by GABA spillover in the mouse dentate gyrus.

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7 January 2021

Behavioural changes produced by transgenic overexpression of gamma2L and gamma2S subunits of the GABAA receptor

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7 January 2021

Trace fear conditioning is enhanced in mice lacking the delta subunit of the GABAA receptor

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954008-6

7 January 2021

Sleep states and sleep electroencephalographic spectral power in mice lacking the beta 3 subunit of the GABA(A) receptor

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7 January 2021

Developmental expression of the alpha 6 GABAA receptor subunit mRNA occurs only after cerebellar granule cell migration.

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954008-6

7 January 2021

Function of gamma-aminobutyric acid receptor/channel rho 1 subunits in spinal cord

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954008-6

7 January 2021

10.1016/S1054-3589(06)54008-6

Identifiers

DOI

1 reference

3 August 2017

1 reference