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The critical role of GRP78 in physiologic and pathologic stress.
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Europe PubMed Central
PMC publication ID
3043145
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20970977%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
title
The critical role of GRP78 in physiologic and pathologic stress
(English)
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stated in
Europe PubMed Central
PMC publication ID
3043145
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20970977%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
author
Amy S Lee
series ordinal
2
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Europe PubMed Central
PMC publication ID
3043145
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20970977%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
author name string
Kyle T Pfaffenbach
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1
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Europe PubMed Central
PMC publication ID
3043145
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20970977%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
publication date
21 October 2010
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Europe PubMed Central
PMC publication ID
3043145
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retrieved
16 February 2020
published in
Current Opinion in Cell Biology
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stated in
Europe PubMed Central
PMC publication ID
3043145
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20970977%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
volume
23
1 reference
stated in
Europe PubMed Central
PMC publication ID
3043145
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20970977%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
issue
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3043145
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20970977%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
page(s)
150-156
1 reference
stated in
Europe PubMed Central
PMC publication ID
3043145
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20970977%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
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Insulin modulates induction of glucose‐regulated protein 78 during endoplasmic reticulum stress via augmentation of ATF4 expression in human neuroblastoma cells
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Akt is the downstream target of GRP78 in mediating cisplatin resistance in ER stress-tolerant human lung cancer cells
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GRP78 as potential predictor for breast cancer response to adjuvant taxane therapy
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Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity
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Ligation of cell surface GRP78 with antibody directed against the COOH-terminal domain of GRP78 suppresses Ras/MAPK and PI 3-kinase/AKT signaling while promoting caspase activation in human prostate cancer cells
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The regulatory subunits of PI3K, p85alpha and p85beta, interact with XBP-1 and increase its nuclear translocation
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A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box-binding protein-1 to modulate the unfolded protein response
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Rapamycin inhibits postprandial-mediated X-box-binding protein-1 splicing in rat liver
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Modulation of the unfolded protein response in prostate cancer cells by antibody-directed against the carboxyl-terminal domain of GRP78.
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Grp78 heterozygosity promotes adaptive unfolded protein response and attenuates diet-induced obesity and insulin resistance
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7 July 2018
p28GANK inhibits endoplasmic reticulum stress-induced cell death via enhancement of the endoplasmic reticulum adaptive capacity
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GRP-78 secreted by tumor cells blocks the antiangiogenic activity of bortezomib
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The tumor suppressor Par-4 activates an extrinsic pathway for apoptosis
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Plasminogen kringle 5 induces apoptosis of brain microvessel endothelial cells: sensitization by radiation and requirement for GRP78 and LRP1.
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7 July 2018
Blockade of Cripto binding to cell surface GRP78 inhibits oncogenic Cripto signaling via MAPK/PI3K and Smad2/3 pathways
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7 July 2018
Ligation of cancer cell surface GRP78 with antibodies directed against its COOH-terminal domain up-regulates p53 activity and promotes apoptosis
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PubMed Central
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7 July 2018
GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice
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7 July 2018
Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight loss
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7 July 2018
Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium
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7 July 2018
Stress chaperone GRP78/BiP confers chemoresistance to tumor-associated endothelial cells
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7 July 2018
Aging impairs the unfolded protein response to sleep deprivation and leads to proapoptotic signaling
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7 July 2018
Insulin-like growth factor-I protects cells from ER stress-induced apoptosis via enhancement of the adaptive capacity of endoplasmic reticulum.
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7 July 2018
The role for endoplasmic reticulum stress in diabetes mellitus
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7 July 2018
Decreased enzyme activities of chaperones PDI and BiP in aged mouse livers
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7 July 2018
GRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor beta signaling and enhance cell growth
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PubMed Central
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7 July 2018
The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas.
1 reference
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PubMed Central
reference URL
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7 July 2018
Glucose-regulated protein GRP78 is up-regulated in prostate cancer and correlates with recurrence and survival.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043145
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7 July 2018
ER chaperones in mammalian development and human diseases
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043145
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7 July 2018
GRP78 induction in cancer: therapeutic and prognostic implications.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043145
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7 July 2018
Mechanistic studies of a peptidic GRP78 ligand for cancer cell-specific drug delivery
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PubMed Central
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7 July 2018
Prostate cancer cell proliferation in vitro is modulated by antibodies against glucose-regulated protein 78 isolated from patient serum
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043145
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7 July 2018
Expression of stress response protein Grp78 is associated with the development of castration-resistant prostate cancer
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043145
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7 July 2018
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043145
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7 July 2018
GRP78 as a novel predictor of responsiveness to chemotherapy in breast cancer
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043145
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7 July 2018
GRP78/BiP is required for cell proliferation and protecting the inner cell mass from apoptosis during early mouse embryonic development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043145
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7 July 2018
The effect of aging on the chaperone concentrations in the hepatic, endoplasmic reticulum of male rats: the possible role of protein misfolding due to the loss of chaperones in the decline in physiological function seen with age
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043145
retrieved
7 July 2018
Activation and cross-talk between Akt, NF-kappaB, and unfolded protein response signaling in 1-LN prostate cancer cells consequent to ligation of cell surface-associated GRP78.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043145
retrieved
7 July 2018
Stress induction of GRP78/BiP and its role in cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043145
retrieved
7 July 2018
From acute ER stress to physiological roles of the Unfolded Protein Response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043145
retrieved
7 July 2018
Cellular environment facilitates protein accumulation in aged rat hippocampus.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043145
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7 July 2018
A trip to the ER: coping with stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043145
retrieved
7 July 2018
Expression of glucose-regulated stress protein GRP78 is related to progression of melanoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043145
retrieved
27 October 2018
Role of the unfolded protein response regulator GRP78/BiP in development, cancer, and neurological disorders.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043145
retrieved
27 October 2018
Critical role of the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043145
retrieved
27 October 2018
The ER chaperone and signaling regulator GRP78/BiP as a monitor of endoplasmic reticulum stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043145
retrieved
27 October 2018
Transgenic mouse model for monitoring endoplasmic reticulum stress in vivo.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043145
retrieved
27 October 2018
Carbonylation of ER chaperone proteins in aged mouse liver
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20970977
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cell surface expression of the stress response chaperone GRP78 enables tumor targeting by circulating ligands
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20970977
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.CEB.2010.09.007
1 reference
stated in
Europe PubMed Central
PMC publication ID
3043145
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20970977%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
PMC publication ID
3043145
1 reference
stated in
Europe PubMed Central
PMC publication ID
3043145
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20970977%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
PubMed publication ID
20970977
1 reference
stated in
Europe PubMed Central
PMC publication ID
3043145
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20970977%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
ResearchGate publication ID
47533774
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