(Q34597807)

3 August 2017

title

Cholesterol modification restricts the spread of Shh gradient in the limb bud. (English)

1 reference

3 August 2017

Yina Li

1

1 reference

3 August 2017

Huimin Zhang

series ordinal

2

1 reference

3 August 2017

Ying Litingtung

series ordinal

3

1 reference

3 August 2017

Chin Chiang

series ordinal

4

1 reference

3 August 2017

language of work or name

English

0 references

publication date

12 April 2006

1 reference

Proceedings of the National Academy of Sciences of the United States of America

3 August 2017

published in

1 reference

3 August 2017

volume

103

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3 August 2017

issue

17

1 reference

3 August 2017

page(s)

6548-6553

1 reference

Cilia and Hedgehog responsiveness in the mouse

3 August 2017

cites work

1 reference

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7 July 2018

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Lipoprotein particles are required for Hedgehog and Wingless signalling

7 July 2018

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Communicating with Hedgehogs

7 July 2018

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LRP2/megalin is required for patterning of the ventral telencephalon

7 July 2018

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Mouse Disp1 is required in sonic hedgehog-expressing cells for paracrine activity of the cholesterol-modified ligand

7 July 2018

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Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6

7 July 2018

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Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities

7 July 2018

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Dynamic changes in the response of cells to positive hedgehog signaling during mouse limb patterning

7 July 2018

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Multiple roles for Nodal in the epiblast of the mouse embryo in the establishment of anterior-posterior patterning

7 July 2018

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The Hedgehog response network: sensors, switches, and routers

7 July 2018

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Patched controls the Hedgehog gradient by endocytosis in a dynamin-dependent manner, but this internalization does not play a major role in signal transduction

7 July 2018

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Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates

7 July 2018

1 reference

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Expression of Sonic hedgehog-Fc fusion protein in Pichia pastoris. Identification and control of post-translational, chemical, and proteolytic modifications

7 July 2018

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Patterning Systems—From One End of the Limb to the Other

7 July 2018

1 reference

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Mouse dispatched mutants fail to distribute hedgehog proteins and are defective in hedgehog signaling

7 July 2018

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Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched

7 July 2018

1 reference

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Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity

7 July 2018

1 reference

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Messenger-RNA-binding proteins and the messages they carry

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458921

Megalin functions as an endocytic sonic hedgehog receptor

7 July 2018

1 reference

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Hedgehog signaling in animal development: paradigms and principles

7 July 2018

1 reference

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Skinny hedgehog, an acyltransferase required for palmitoylation and activity of the hedgehog signal

7 July 2018

1 reference

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Manifestation of the limb prepattern: limb development in the absence of sonic hedgehog function

7 July 2018

1 reference

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The whereabouts of a morphogen: direct evidence for short- and graded long-range activity of hedgehog signaling peptides

7 July 2018

1 reference

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A freely diffusible form of Sonic hedgehog mediates long-range signalling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458921

Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458921

Receptor-mediated endocytosis of soluble and membrane-tethered Sonic hedgehog by Patched-1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458921

High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458921

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458921

Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458921

Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458921

Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458921

The roles of FGFs in the early development of vertebrate limbs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458921

Identification of a palmitic acid-modified form of human Sonic hedgehog

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458921

Molecular models for vertebrate limb development

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458921

Dual roles for patched in sequestering and transducing Hedgehog

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458921

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458921

Cholesterol modification of hedgehog signaling proteins in animal development

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458921

Hedgehog patterning activity: role of a lipophilic modification mediated by the carboxy-terminal autoprocessing domain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458921

Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458921

A positive feedback loop coordinates growth and patterning in the vertebrate limb.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458921

Proteolytic processing yields two secreted forms of sonic hedgehog

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458921

Sightless has homology to transmembrane acyltransferases and is required to generate active Hedgehog protein

7 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0600124103

Mouse Dispatched homolog1 is required for long-range, but not juxtacrine, Hh signaling

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0600124103

Efficient gene modulation in mouse epiblast using a Sox2Cre transgenic mouse strain

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0600124103

Relationship between dose, distance and time in Sonic Hedgehog-mediated regulation of anteroposterior polarity in the chick limb.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458921

26 October 2018

Identifiers

DOI

10.1073/PNAS.0600124103

1 reference

3 August 2017

0 references

1 reference

3 August 2017

1 reference