(Q34600067)

3 August 2017

1 reference

title

The many faces of H89: a review (English)

1 reference

3 August 2017

A Lochner

1

1 reference

PubMed ID

17214602

3 August 2017

J A Moolman

series ordinal

2

1 reference

3 August 2017

1 September 2006

1 reference

Cardiovascular Drug Reviews

3 August 2017

1 reference

3 August 2017

24

1 reference

3 August 2017

3-4

1 reference

3 August 2017

261-274

1 reference

Phosphorylation modulates catalytic function and regulation in the cAMP-dependent protein kinase

3 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

The specificities of protein kinase inhibitors: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Effects of the PKA inhibitor H-89 on excitation-contraction coupling in skinned and intact skeletal muscle fibres

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Protein kinases--structure and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Crystallography for protein kinase drug design: PKA and SRC case studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Expression of TNFalpha and its receptors R1 and R2 in human alveolar epithelial cells exposed to organic dust and the effects of 8-bromo-cAMP and protein kinase A modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Recent kinase and kinase inhibitor X-ray structures: mechanisms of inhibition and selectivity insights

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Inhibition of Kv1.3 channels by H-89 (N--[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide) independent of protein kinase A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Protein kinase inhibitor peptide (PKI): a family of endogenous neuropeptides that modulate neuronal cAMP-dependent protein kinase function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Specificity and mechanism of action of some commonly used protein kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Proteomic analysis of rat liver phosphoproteins after treatment with protein kinase inhibitor H89 (N-(2-[p-bromocinnamylamino-]ethyl)-5-isoquinolinesulfonamide).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Isolation and properties of the rabbit skeletal muscle protein inhibitor of adenosine 3',5'-monophosphate dependent protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Biphasic modulation of nociceptive processing by the cyclic AMP-protein kinase A signalling pathway in sheep spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

cAMP-induced morphological changes are counteracted by the activated RhoA small GTPase and the Rho kinase ROKalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Crystal structures of catalytic subunit of cAMP-dependent protein kinase in complex with isoquinolinesulfonyl protein kinase inhibitors H7, H8, and H89. Structural implications for selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Nitric oxide-dependent beta2-adrenergic dilatation of rat aorta is mediated through activation of both protein kinase A and Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

The design of drug candidate molecules as selective inhibitors of therapeutically relevant protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Novel (Rp)-cAMPS analogs as tools for inhibition of cAMP-kinase in cell culture. Basal cAMP-kinase activity modulates interleukin-1 beta action

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Protein kinase catalytic domain sequence database: identification of conserved features of primary structure and classification of family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Molecular pharmacology of protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Properties and use of H-series compounds as protein kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Gbetagamma-mediated regulation of Golgi organization is through the direct activation of protein kinase D

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Evolving concepts of partial agonism. The beta-adrenergic receptor as a paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Dynamics of cAMP-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Possible involvement of p38 MAP kinase in prostaglandin E1-induced ALP activity in osteoblast-like cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

3',5'-cyclic adenosine monophosphate augments intracellular Ca2+ concentration and gonadotropin-releasing hormone (GnRH) release in immortalized GnRH neurons in an Na+ -dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Crystal structure of a complex between the catalytic and regulatory (RIalpha) subunits of PKA

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Involvement of protein kinase A in cannabinoid receptor-mediated protection from oxidative neuronal injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Crystal Structure of the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

The protein kinase A inhibitor H89 acts on cell morphology by inhibiting Rho kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Differential roles of spinal protein kinases C and a in development of primary heat and mechanical hypersensitivity induced by subcutaneous bee venom chemical injury in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

cAMP and protein kinase A contribute to the downregulation of spinal glutamate transporters after chronic morphine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Inhibitors of protein kinases and phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

H-89, a non-specific inhibitor of protein kinase A, promotes post-ischemic cardiac contractile recovery and reduces infarct size

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Protein kinase regulation: insights from crystal structure analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Protein kinase A activity is required for the budding of constitutive transport vesicles from the trans-Golgi network

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Parathyroid hormone induces receptor activity modifying protein-3 (RAMP3) expression primarily via 3',5'-cyclic adenosine monophosphate signaling in osteoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

PI 3-kinase, protein kinase C, and protein kinase A are involved in the trigger phase of beta1-adrenergic preconditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Catecholamine cardiotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Elevated cAMP suppresses muscarinic inhibition of L-type calcium current in guinea pig ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

The potentiation of nitroglycerin-induced relaxation by PKG inhibition in rat aortic rings.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

High affinity targets of protein kinase inhibitors have similar residues at the positions energetically important for binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

H-89 inhibits collagenase induction by phorbol ester through a mechanism that does not involve protein kinase A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Mechanism of cicaprost-induced desensitization in rat pulmonary artery smooth muscle cells involves a PKA-mediated inhibition of adenylyl cyclase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Direct inhibition of a PKA inhibitor, H-89 on KV channels in rabbit coronary arterial smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

The protein kinase A inhibitor, H-89, directly inhibits KATP and Kir channels in rabbit coronary arterial smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

A possible role of noradrenaline in the development of myocardial infarction: an experimental study in the isolated rat heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

N-[2-bromocinnamyl(amino)ethyl]-5-isoquinolinesulphonamide (H-89) inhibits incorporation of choline into phosphatidylcholine via inhibition of choline kinase and has no effect on the phosphorylation of CTP:phosphocholine cytidylyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Latest developments in crystallography and structure-based design of protein kinase inhibitors as drug candidates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

ADP-ribosyl cyclase couples to cyclic AMP signaling in the cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

Protein kinase A phosphorylation modulates transport of the polypyrimidine tract-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

JNK signaling involved in the effects of cyclic AMP on IL-1beta plus IFNgamma-induced inducible nitric oxide synthase expression in hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00261.X

10.1111/J.1527-3466.2006.00261.X

21 January 2018

Identifiers

DOI

1 reference

3 August 2017

1 reference

PubMed ID

17214602