(Q34603310)

25239010

3 August 2017

title

Mitochondria-derived reactive oxygen species mediate caspase-dependent and -independent neuronal deaths (English)

1 reference

3 August 2017

1 reference

reactive oxygen species

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25239010%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

author name string

Meagan J McManus

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25239010%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

James L Franklin

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25239010%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

language of work or name

1 reference

16 September 2014

1 reference

25239010

Molecular and Cellular Neuroscience

3 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25239010%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

volume

63

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25239010%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

page(s)

13-23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25239010%20AND%20SRC:MED&resulttype=core&format=json

MitoQ, a mitochondria-targeted antioxidant, delays disease progression and alleviates pathogenesis in an experimental autoimmune encephalomyelitis mouse model of multiple sclerosis

2 June 2020

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1 reference

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The mitochondria-targeted antioxidant MitoQ prevents loss of spatial memory retention and early neuropathology in a transgenic mouse model of Alzheimer's disease.

7 July 2018

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7 July 2018

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Bax regulates production of superoxide in both apoptotic and nonapoptotic neurons: role of caspases

7 July 2018

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Prevention of diabetic nephropathy in Ins2(+/)⁻(AkitaJ) mice by the mitochondria-targeted therapy MitoQ.

7 July 2018

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Redox Regulation of the Intrinsic Pathway in Neuronal Apoptosis

7 July 2018

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Animal and human studies with the mitochondria-targeted antioxidant MitoQ.

7 July 2018

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A double-blind, placebo-controlled study to assess the mitochondria-targeted antioxidant MitoQ as a disease-modifying therapy in Parkinson's disease

7 July 2018

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Diminished NADPH transhydrogenase activity and mitochondrial redox regulation in human failing myocardium

7 July 2018

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Poly(ADP-ribose) polymerase (PARP)-1-independent apoptosis-inducing factor (AIF) release and cell death are induced by eleostearic acid and blocked by alpha-tocopherol and MEK inhibition

7 July 2018

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Reactive oxygen species, cellular redox systems, and apoptosis

7 July 2018

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Pharmacomimetics of exercise: novel approaches for hippocampally-targeted neuroprotective agents

7 July 2018

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Apoptosis and glutathione: beyond an antioxidant.

7 July 2018

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Tau pathophysiology in neurodegeneration: a tangled issue

7 July 2018

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How mitochondria produce reactive oxygen species

7 July 2018

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Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c.

7 July 2018

1 reference

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The mitochondria-targeted antioxidant MitoQ protects against organ damage in a lipopolysaccharide-peptidoglycan model of sepsis.

7 July 2018

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Glucose-6-phosphate dehydrogenase--from oxidative stress to cellular functions and degenerative diseases

7 July 2018

1 reference

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Interaction of the mitochondria-targeted antioxidant MitoQ with phospholipid bilayers and ubiquinone oxidoreductases

7 July 2018

1 reference

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Mitochondrial membrane permeabilization in cell death

7 July 2018

1 reference

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Mitochondrial isocitrate dehydrogenase protects human neuroblastoma SH-SY5Y cells against oxidative stress

7 July 2018

1 reference

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Selective fluorescent imaging of superoxide in vivo using ethidium-based probes

7 July 2018

1 reference

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A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine

7 July 2018

1 reference

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Interactions of mitochondria-targeted and untargeted ubiquinones with the mitochondrial respiratory chain and reactive oxygen species. Implications for the use of exogenous ubiquinones as therapies and experimental tools

7 July 2018

1 reference

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Caspase-dependent and -independent neuronal death: two distinct pathways to neuronal injury

7 July 2018

1 reference

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Mitochondria in health and disease: perspectives on a new mitochondrial biology

7 July 2018

1 reference

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The pathophysiology of mitochondrial cell death

7 July 2018

1 reference

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Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain

7 July 2018

1 reference

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Antioxidant and prooxidant properties of mitochondrial Coenzyme Q.

7 July 2018

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The cardiolipin-cytochrome c interaction and the mitochondrial regulation of apoptosis

7 July 2018

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Men are but worms: neuronal cell death in C elegans and vertebrates

7 July 2018

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Mitochondrial formation of reactive oxygen species

7 July 2018

1 reference

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Alternating metabolic pathways in NGF-deprived sympathetic neurons affect caspase-independent death

7 July 2018

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Delivery of bioactive molecules to mitochondria in vivo.

7 July 2018

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Apoptosis and caspases in neurodegenerative diseases

7 July 2018

1 reference

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Mitochondrial involvement in the point of no return in neuronal apoptosis

7 July 2018

1 reference

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Cyclosporin A inhibits caspase-independent death of NGF-deprived sympathetic neurons: a potential role for mitochondrial permeability transition

7 July 2018

1 reference

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Mitochondrial permeability transition and oxidative stress

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4250393

Evidence for redox regulation of cytochrome C release during programmed neuronal death: antioxidant effects of protein synthesis and caspase inhibition.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4250393

Selective targeting of a redox-active ubiquinone to mitochondria within cells: antioxidant and antiapoptotic properties

7 July 2018

1 reference

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Preservation of mitochondrial structure and function after Bid- or Bax-mediated cytochrome c release

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4250393

Caspase inhibition extends the commitment to neuronal death beyond cytochrome c release to the point of mitochondrial depolarization

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4250393

Inhibition of apoptotic signaling cascades causes loss of trophic factor dependence during neuronal maturation

7 July 2018

1 reference

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Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts

7 July 2018

1 reference

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Selective targeting of an antioxidant to mitochondria

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4250393

Review: The role of glutathione in the regulation of apoptosis

7 July 2018

1 reference

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Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

7 July 2018

1 reference

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Contributions of mitochondria to animal physiology: from homeostatic sensor to calcium signalling and cell death

7 July 2018

1 reference

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Blocking cytochrome c activity within intact neurons inhibits apoptosis.

7 July 2018

1 reference

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Antioxidant properties of 2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone (idebenone).

7 July 2018

1 reference

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Programmed cell death in neurons: focus on the pathway of nerve growth factor deprivation-induced death of sympathetic neurons.

7 July 2018

1 reference

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Rapid suppression of free radical formation by nerve growth factor involves the mitogen-activated protein kinase pathway

7 July 2018

1 reference

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The neurotrophic hypothesis: where does it stand?

7 July 2018

1 reference

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The regulation of hepatic glutathione

7 July 2018

1 reference

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High-affinity transport of glutathione is part of a multicomponent system essential for mitochondrial function

7 July 2018

1 reference

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Vitamin E: antioxidant activity, biokinetics, and bioavailability

7 July 2018

1 reference

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Mitochondria-targeted antioxidants as promising drugs for treatment of age-related brain diseases

7 July 2018

1 reference

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The epigenome and the mitochondrion: bioenergetics and the environment [corrected].

26 October 2018

1 reference

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The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C patients

26 October 2018

1 reference

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The identity and regulation of the mitochondrial permeability transition pore: where the known meets the unknown

26 October 2018

1 reference

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Rapid and extensive uptake and activation of hydrophobic triphenylphosphonium cations within cells

26 October 2018

1 reference

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Rapid activation of antioxidant defenses by nerve growth factor suppresses reactive oxygen species during neuronal apoptosis: evidence for a role in cytochrome c redistribution.

26 October 2018

1 reference

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'Mild Uncoupling' does not decrease mitochondrial superoxide levels in cultured cerebellar granule neurons but decreases spare respiratory capacity and increases toxicity to glutamate and oxidative stress

26 October 2018

1 reference

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Reactive oxygen species induced by proteasome inhibition in neuronal cells mediate mitochondrial dysfunction and a caspase-independent cell death.

26 October 2018

1 reference

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Apoptosome dependent caspase-3 activation pathway is non-redundant and necessary for apoptosis in sympathetic neurons

26 October 2018

1 reference

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Autophagy contributes to caspase-independent macrophage cell death

26 October 2018

1 reference

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Caspase-independent component of retinal ganglion cell death, in vitro

26 October 2018

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Fine-tuning the hydrophobicity of a mitochondria-targeted antioxidant

26 October 2018

1 reference

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Mechanisms of caspase-independent neuronal death: energy depletion and free radical generation.

26 October 2018

1 reference

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Imaging mitochondrial function in intact cells

26 October 2018

1 reference

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Loss of cardiolipin and mitochondria during programmed neuronal death: evidence of a role for lipid peroxidation and autophagy

26 October 2018

1 reference

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Tumor necrosis factor alpha induces a caspase-independent death pathway in human neutrophils

26 October 2018

1 reference

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A Bax-induced pro-oxidant state is critical for cytochrome c release during programmed neuronal death.

26 October 2018

1 reference

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Techniques in the tissue culture of rat sympathetic neurons

26 October 2018

1 reference

12 December 2020

Reactivity of ubiquinone and ubiquinol with superoxide and the hydroperoxyl radical: implications for in vivo antioxidant activity

1 reference

12 December 2020

N-Acetylcysteine-promoted Survival of PC12 Cells Is Glutathione-independent but Transcription-dependent

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12 December 2020

Recycling and redox cycling of phenolic antioxidants

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12 December 2020

BAX translocation is a critical event in neuronal apoptosis: regulation by neuroprotectants, BCL-2, and caspases

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12 December 2020

Mitochondrially targeted antioxidants for the treatment of cardiovascular diseases

1 reference

12 December 2020

Evidence of a novel event during neuronal death: development of competence-to-die in response to cytoplasmic cytochrome c

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12 December 2020

Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death

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12 December 2020

10.1016/J.MCN.2014.09.002

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25239010%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25239010%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

25239010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25239010%20AND%20SRC:MED&resulttype=core&format=json