(Q34605176)

3 August 2017

title

Ah receptor antagonism inhibits constitutive and cytokine inducible IL6 production in head and neck tumor cell lines (English)

1 reference

3 August 2017

main subject

head and neck neoplasms

1 reference

Brett C. DiNatale

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21104991

2 September 2024

Jennifer C. Schroeder

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21104991

2 September 2024

Gary H. Perdew

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21104991

2 September 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21104991

2 September 2024

publication date

23 November 2010

1 reference

full work available at URL

3 August 2017

https://europepmc.org/articles/pmc3044777?pdf=render

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21104991

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21104991/?tool=EBI

2 September 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21104991

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21104991/pdf/?tool=EBI

2 September 2024

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21104991

https://europepmc.org/articles/PMC3044777

2 September 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21104991

https://europepmc.org/articles/PMC3044777?pdf=render

2 September 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21104991

https://doi.org/10.1002/mc.20702

2 September 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21104991

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fmc.20702

2 September 2024

1 reference

https://api.crossref.org/works/10.1002/MC.20702

https://onlinelibrary.wiley.com/doi/pdf/10.1002/mc.20702

2 September 2024

1 reference

https://api.crossref.org/works/10.1002/MC.20702

2 September 2024

published in

Molecular Carcinogenesis

1 reference

3 August 2017

volume

50

1 reference

3 August 2017

issue

3

1 reference

3 August 2017

page(s)

173-183

1 reference

Mechanistic insights into the events that lead to synergistic induction of interleukin 6 transcription upon activation of the aryl hydrocarbon receptor and inflammatory signaling.

3 August 2017

cites work

1 reference

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Development of a selective modulator of aryl hydrocarbon (Ah) receptor activity that exhibits anti-inflammatory properties

7 July 2018

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Antitumor effects of lapatinib (GW572016), a dual inhibitor of EGFR and HER-2, in combination with cisplatin or paclitaxel on head and neck squamous cell carcinoma

7 July 2018

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Kynurenic acid is a potent endogenous aryl hydrocarbon receptor ligand that synergistically induces interleukin-6 in the presence of inflammatory signaling

7 July 2018

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The aryl hydrocarbon receptor (AhR) in the regulation of cell-cell contact and tumor growth.

7 July 2018

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The uremic toxin 3-indoxyl sulfate is a potent endogenous agonist for the human aryl hydrocarbon receptor

7 July 2018

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Antagonism of aryl hydrocarbon receptor signaling by 6,2',4'-trimethoxyflavone

7 July 2018

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Guggulsterone enhances head and neck cancer therapies via inhibition of signal transducer and activator of transcription-3

7 July 2018

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Activation of the aryl hydrocarbon receptor pathway enhances cancer cell invasion by upregulating the MMP expression and is associated with poor prognosis in upper urinary tract urothelial cancer.

7 July 2018

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Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in ApcMin/+ mice with natural ligands

7 July 2018

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Nedd9/Hef1/Cas-L mediates the effects of environmental pollutants on cell migration and plasticity

7 July 2018

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Complications of radiotherapy in laryngopharyngeal cancer: effects of a prospective smoking cessation program

7 July 2018

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The aryl hydrocarbon receptor: a perspective on potential roles in the immune system

7 July 2018

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Crosstalk between activated forms of the aryl hydrocarbon receptor and glucocorticoid receptor

7 July 2018

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The aryl hydrocarbon receptor as a target for estrogen receptor-negative breast cancer chemotherapy

7 July 2018

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Aryl hydrocarbon receptor pathway activation enhances gastric cancer cell invasiveness likely through a c-Jun-dependent induction of matrix metalloproteinase-9.

7 July 2018

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Fascin-1 promoter activity is regulated by CREB and the aryl hydrocarbon receptor in human carcinoma cells

7 July 2018

1 reference

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Ah receptor represses acute-phase response gene expression without binding to its cognate response element

7 July 2018

1 reference

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The selective aryl hydrocarbon receptor modulator 6-methyl-1,3,8-trichlorodibenzofuran inhibits prostate tumor metastasis in TRAMP mice.

7 July 2018

1 reference

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The dioxin receptor regulates the constitutive expression of the vav3 proto-oncogene and modulates cell shape and adhesion.

7 July 2018

1 reference

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A new cross-talk between the aryl hydrocarbon receptor and RelB, a member of the NF-kappaB family

7 July 2018

1 reference

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Roles of coactivator proteins in dioxin induction of CYP1A1 and CYP1B1 in human breast cancer cells

7 July 2018

1 reference

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Human head and neck squamous cell carcinoma cells are both targets and effectors for the angiogenic cytokine, VEGF.

7 July 2018

1 reference

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12(R)-Hydroxy-5(Z),8(Z),10(E),14(Z)-eicosatetraenoic acid [12(R)-HETE], an arachidonic acid derivative, is an activator of the aryl hydrocarbon receptor

7 July 2018

1 reference

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Leukotriene A4 metabolites are endogenous ligands for the Ah receptor

7 July 2018

1 reference

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Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of Th17 cells.

7 July 2018

1 reference

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The aryl hydrocarbon receptor complex and the control of gene expression

7 July 2018

1 reference

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Inflammatory signaling and aryl hydrocarbon receptor mediate synergistic induction of interleukin 6 in MCF-7 cells

7 July 2018

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The BRG1 transcriptional coregulator

7 July 2018

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IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland

7 July 2018

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Interleukin-6 is a potent growth factor for ER-alpha-positive human breast cancer

7 July 2018

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Oestrogen receptor negative breast cancers exhibit high cytokine content

7 July 2018

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Targeting constitutive and interleukin-6-inducible signal transducers and activators of transcription 3 pathway in head and neck squamous cell carcinoma cells by curcumin (diferuloylmethane).

7 July 2018

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Secretion of tumor-promoting and immune suppressive cytokines by cell lines of head and neck squamous cell carcinoma

7 July 2018

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Apical role for BRG1 in cytokine-induced promoter assembly

7 July 2018

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Benzo-[a]-pyrene increases invasion in MDA-MB-231 breast cancer cells via increased COX-II expression and prostaglandin E2 (PGE2) output

7 July 2018

1 reference

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Mechanisms of inhibitory aryl hydrocarbon receptor-estrogen receptor crosstalk in human breast cancer cells

7 July 2018

1 reference

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Treatment of locally advanced head and neck cancer: historical and critical review

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044777

Functional involvement of the Brahma/SWI2-related gene 1 protein in cytochrome P4501A1 transcription mediated by the aryl hydrocarbon receptor complex

7 July 2018

1 reference

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Autocrine production of interleukin 6 causes multidrug resistance in breast cancer cells.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044777

Interleukin 6 inhibits proliferation and, in cooperation with an epidermal growth factor receptor autocrine loop, increases migration of T47D breast cancer cells.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044777

The effects of IL-6 on cell adhesion and e-cadherin expression in breast cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044777

Variable expression of cytokines in human head and neck squamous cell carcinoma cell lines and consistent expression in surgical specimens.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044777

Antiestrogenic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin are mediated by direct transcriptional interference with the liganded estrogen receptor. Cross-talk between aryl hydrocarbon- and estrogen-mediated signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044777

MTS1/CDK4I is altered in cell lines derived from primary and metastatic oral squamous cell carcinoma

7 July 2018

1 reference

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The pleiotropy of dioxin toxicity--xenobiotic misappropriation of the aryl hydrocarbon receptor's alternative physiological roles.

7 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FMC.20702

Polycyclic aromatic hydrocarbons inhibit differentiation of human monocytes into macrophages

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FMC.20702

Epidermal growth factor receptor-independent constitutive activation of STAT3 in head and neck squamous cell carcinoma is mediated by the autocrine/paracrine stimulation of the interleukin 6/gp130 cytokine system.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044777

Curcumin activates the aryl hydrocarbon receptor yet significantly inhibits (-)-benzo(a)pyrene-7R-trans-7,8-dihydrodiol bioactivation in oral squamous cell carcinoma cells and oral mucosa.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044777

The antiapoptotic effect of IL-6 autocrine loop in a cellular model of advanced prostate cancer is mediated by Mcl-1

26 October 2018

1 reference

12 December 2020

TCDD deregulates contact inhibition in rat liver oval cells via Ah receptor, JunD and cyclin A

1 reference

12 December 2020

Interleukin-6 predicts recurrence and survival among head and neck cancer patients

1 reference

12 December 2020

Expression of Stat3 and Notch1 is associated with cisplatin resistance in head and neck squamous cell carcinoma

1 reference

12 December 2020

Influence of cigarette smoking on the efficacy of radiation therapy in head and neck cancer

1 reference

12 December 2020

Expression of proinflammatory and proangiogenic cytokines in patients with head and neck cancer

1 reference

12 December 2020

Identifiers

DOI

10.1002/MC.20702

1 reference

3 August 2017

1 reference

3 August 2017

1 reference