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Analysis of Sir2p domains required for rDNA and telomeric silencing in Saccharomyces cerevisiae.
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Europe PubMed Central
PMCID
1461001
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10757754%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
title
Analysis of Sir2p domains required for rDNA and telomeric silencing in Saccharomyces cerevisiae
(English)
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Europe PubMed Central
PMCID
1461001
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10757754%20AND%20SRC:MED&resulttype=core&format=json
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5 November 2019
main subject
Saccharomyces cerevisiae
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author
Susan M. Gasser
series ordinal
3
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Europe PubMed Central
PMCID
1461001
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10757754%20AND%20SRC:MED&resulttype=core&format=json
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5 November 2019
author name string
Cockell MM
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
1461001
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10757754%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
Perrod S
series ordinal
2
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Europe PubMed Central
PMCID
1461001
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10757754%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
language of work or name
English
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publication date
1 March 2000
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Europe PubMed Central
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1461001
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10757754%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
number of pages
15
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published in
Genetics
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stated in
Europe PubMed Central
PMCID
1461001
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10757754%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
volume
154
1 reference
stated in
Europe PubMed Central
PMCID
1461001
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10757754%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
page(s)
1069-1083
1 reference
stated in
Europe PubMed Central
PMCID
1461001
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10757754%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
issue
3
1 reference
stated in
Europe PubMed Central
PMCID
1461001
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10757754%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
cites work
An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
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7 July 2018
The Schizosaccharomyces pombe hst4(+) gene is a SIR2 homologue with silencing and centromeric functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
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7 July 2018
The conserved core of a human SIR2 homologue functions in yeast silencing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
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7 July 2018
Targeting Sir proteins to sites of action: a general mechanism for regulated repression.
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PubMed Central
reference URL
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7 July 2018
Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
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7 July 2018
Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast
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PubMed Central
reference URL
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7 July 2018
Crystal structure of the human protein kinase CK2 regulatory subunit reveals its zinc finger-mediated dimerization
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PubMed Central
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7 July 2018
Phenotypic switching in Candida albicans is controlled by a SIR2 gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
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7 July 2018
Net1, a Sir2-associated nucleolar protein required for rDNA silencing and nucleolar integrity
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
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7 July 2018
A region of the Sir1 protein dedicated to recognition of a silencer and required for interaction with the Orc1 protein in saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
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7 July 2018
Functional characterization of the N terminus of Sir3p
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
retrieved
7 July 2018
Sif2p interacts with Sir4p amino-terminal domain and antagonizes telomeric silencing in yeast.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
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7 July 2018
Distribution of a limited Sir2 protein pool regulates the strength of yeast rDNA silencing and is modulated by Sir4p
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
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7 July 2018
Extrachromosomal rDNA circles--a cause of aging in yeast
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
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7 July 2018
Direct evidence for SIR2 modulation of chromatin structure in yeast rDNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
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7 July 2018
Histone deacetylases, acetoin utilization proteins and acetylpolyamine amidohydrolases are members of an ancient protein superfamily
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
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7 July 2018
Localization of Sir2p: the nucleolus as a compartment for silent information regulators
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
retrieved
7 July 2018
Silent information regulator protein complexes in Saccharomyces cerevisiae: a SIR2/SIR4 complex and evidence for a regulatory domain in SIR4 that inhibits its interaction with SIR3.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
retrieved
7 July 2018
Hyperactivation of the silencing proteins, Sir2p and Sir3p, causes chromosome loss
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
retrieved
7 July 2018
SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
retrieved
7 July 2018
Activation of an MAP kinase cascade leads to Sir3p hyperphosphorylation and strengthens transcriptional silencing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
retrieved
7 July 2018
The clustering of telomeres and colocalization with Rap1, Sir3, and Sir4 proteins in wild-type Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
retrieved
7 July 2018
HST1, a new member of the SIR2 family of genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
retrieved
7 July 2018
Using CLUSTAL for multiple sequence alignments
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
retrieved
7 July 2018
Cooperation at a distance between silencers and proto-silencers at the yeast HML locus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
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7 July 2018
A Leishmania major protein with extensive homology to silent information regulator 2 of Saccharomyces cerevisiae.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
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7 July 2018
Tethered Sir3p nucleates silencing at telomeres and internal loci in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
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7 July 2018
Role of interactions between the origin recognition complex and SIR1 in transcriptional silencing
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
retrieved
7 July 2018
Chromatin structures and transcription of rDNA in yeast Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
retrieved
7 July 2018
Transcriptional silencing in yeast is associated with reduced nucleosome acetylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
retrieved
7 July 2018
Zinc fingers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
retrieved
7 July 2018
Evidence that a complex of SIR proteins interacts with the silencer and telomere-binding protein RAP1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
retrieved
7 July 2018
Interaction of the yeast RAD7 and SIR3 proteins: implications for DNA repair and chromatin structure
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
retrieved
7 July 2018
Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
retrieved
7 July 2018
The carboxy termini of Sir4 and Rap1 affect Sir3 localization: evidence for a multicomponent complex required for yeast telomeric silencing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
retrieved
7 July 2018
Yeast vectors for the controlled expression of heterologous proteins in different genetic backgrounds
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
retrieved
7 July 2018
TLC1: template RNA component of Saccharomyces cerevisiae telomerase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
retrieved
7 July 2018
The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
retrieved
7 July 2018
Functional domains of SIR4, a gene required for position effect regulation in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
retrieved
7 July 2018
A replication fork barrier at the 3' end of yeast ribosomal RNA genes
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
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7 July 2018
A new role for a yeast transcriptional silencer gene, SIR2, in regulation of recombination in ribosomal DNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
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7 July 2018
Relation between carcinogenesis, chromatin structure and poly(ADP-ribosylation) (review).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
retrieved
7 July 2018
CobB, a new member of the SIR2 family of eucaryotic regulatory proteins, is required to compensate for the lack of nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase activity in cobT mutants during cobalamin biosynthesis i
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
retrieved
26 October 2018
Silent chromatin in yeast: an orchestrated medley featuring Sir3p [corrected]
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
retrieved
26 October 2018
A deubiquitinating enzyme interacts with SIR4 and regulates silencing in S. cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
retrieved
26 October 2018
Replicon size of yeast ribosomal DNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1461001
retrieved
26 October 2018
Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10757754
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Evidence for silencing compartments within the yeast nucleus: a role for telomere proximity and Sir protein concentration in silencer-mediated repression
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10757754
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10757754
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
PMCID
1461001
1 reference
stated in
Europe PubMed Central
PMCID
1461001
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10757754%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
PubMed ID
10757754
1 reference
stated in
Europe PubMed Central
PMCID
1461001
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10757754%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
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