(Q34609472)

3 August 2017

title

Natural and semisynthetic mammea-type isoprenylated dihydroxycoumarins uncouple cellular respiration (English)

1 reference

5,7-dihydroxy-6-[(2R)-2-methylbutanoyl]-8-(3-methylbut-2-enyl)-4-propylchromen-2-one

3 August 2017

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5,7-dihydroxy-6-(3-methylbut-2-enyl)-8-(3-methylbutanoyl)-4-pentyl-2H-chromen-2-one

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Lin Du

1

1 reference

3 August 2017

Fakhri Mahdi

2

1 reference

3 August 2017

Mika B Jekabsons

3

1 reference

3 August 2017

Dale G Nagle

4

1 reference

3 August 2017

Yu-Dong Zhou

5

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3 August 2017

publication date

7 January 2011

1 reference

full work available at URL

3 August 2017

https://europepmc.org/articles/pmc3045645?pdf=render

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1021/np100762s?email=unpaywall_01@example.com

published in

Journal of Natural Products

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3 August 2017

volume

74

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3 August 2017

issue

2

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3 August 2017

page(s)

240-248

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https://api.unpaywall.org/v2/10.1021/np100762s?email=unpaywall_01@example.com

3 August 2017

1 reference

19 March 2024

access restriction status

open access

1 reference

based on heuristic

inferred from online access status

cites work

Mammea E/BB, an isoprenylated dihydroxycoumarin protonophore that potently uncouples mitochondrial electron transport, disrupts hypoxic signaling in tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045645

Marine Natural Products as Inhibitors of Hypoxic Signaling in Tumors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045645

Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045645

The structure and pharmacological functions of coumarins and their derivatives

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045645

Methylalpinumisoflavone inhibits hypoxia-inducible factor-1 (HIF-1) activation by simultaneously targeting multiple pathways

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045645

Hypoxia in cancer: significance and impact on clinical outcome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045645

Natural products as sources of new drugs over the last 25 years

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045645

Targeting VEGF-A to treat cancer and age-related macular degeneration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045645

Antioxidant and cytotoxic isoprenylated coumarins from Mammea americana.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045645

Terpenoid tetrahydroisoquinoline alkaloids emetine, klugine, and isocephaeline inhibit the activation of hypoxia-inducible factor-1 in breast tumor cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045645

Synthetic and natural coumarins as cytotoxic agents

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045645

Cytotoxic effects of mammea type coumarins from Calophyllum brasiliense.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045645

Biologically active alkylated coumarins from Kayea assamica

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045645

Mechanism of inhibition by uncouples of succinate oxidation in isolated mitochondria

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045645

Effect of coumarins on mitochondrial function I. Uncoupling of oxidative phosphorylation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045645

Effect of coumarins on mitochondrial function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045645

4-Alkyl- and 4-phenylcoumarins from Mesua ferrea as promising multidrug resistant antibacterials

7 July 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21214226

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/NP100762S

1 reference

3 August 2017

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3 August 2017

1 reference