(Q34615857)

3 August 2017

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title

Molecular bases of cellular iron toxicity (English)

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3 August 2017

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John W Eaton

1

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3 August 2017

Mingwei Qian

series ordinal

2

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3 August 2017

publication date

1 May 2002

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Free Radical Biology and Medicine

3 August 2017

published in

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3 August 2017

volume

32

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3 August 2017

issue

9

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3 August 2017

page(s)

833-840

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Survival and causes of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis

3 August 2017

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Cardiac iron deposition in idiopathic hemochromatosis: histologic and analytic assessment of 14 hearts from autopsy

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Iron overload cardiomyopathies: new insights into an old disease

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Cardiac Wilson's disease

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Ultrastructural and cytochemical changes in the heart of iron-deficient rats

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7 January 2021

Beta-cells, oxidative stress, lysosomal stability, and apoptotic/necrotic cell death

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7 January 2021

Endothelial-cell heme uptake from heme proteins: induction of sensitization and desensitization to oxidant damage

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7 January 2021

Thalassaemic erythrocytes: cellular suicide arising from iron and glutathione-dependent oxidation reactions?

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The role of mitochondrial glutathione in DNA base oxidation.

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Enhanced γ-Glutamyl Transpeptidase Expression and Selective Loss of CuZn Superoxide Dismutase in Hepatic Iron Overload

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7 January 2021

Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase

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7 January 2021

A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase

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7 January 2021

Mitochondrial disease in superoxide dismutase 2 mutant mice

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7 January 2021

Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice

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7 January 2021

Hydroperoxide metabolism in mammalian organs

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7 January 2021

A short exposure to a high-glucose milieu stabilizes the acidic vacuolar apparatus of insulinoma cells in culture to ensuing oxidative stress

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7 January 2021

Insulinoma cells in culture show pronounced sensitivity to alloxan-induced oxidative stress

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7 January 2021

Liver injury due to iron overload in thalassemia: histopathologic and ultrastructural studies

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7 January 2021

Comparison of the structural changes induced by doxorubicin and mitoxantrone in the heart, kidney and intestine and characterization of the Fe(III)-mitoxantrone complex

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7 January 2021

Giant mitochondria induced in rat pancreatic exocrine cells by ethanol and iron

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7 January 2021

Pathophysiology of iron toxicity.

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7 January 2021

Hepatic lipid peroxidation in vivo in rats with chronic iron overload

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7 January 2021

Iron-induced peroxidative injury to isolated rat hepatic mitochondria

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7 January 2021

Lipid peroxidation in experimental hemochromatosis

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7 January 2021

Cardioprotective effect of alpha-tocopherol, ascorbate, deferoxamine, and deferiprone: mitochondrial function in cultured, iron-loaded heart cells

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7 January 2021

Role of oxidants in DNA damage. Hydroxyl radical mediates the synergistic DNA damaging effects of asbestos and cigarette smoke

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7 January 2021

Oxidant-induced DNA damage of target cells

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7 January 2021

Hydrogen peroxide-induced DNA damage is independent of nuclear calcium but dependent on redox-active ions

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7 January 2021

Nucleosomal histone protein protects DNA from iron-mediated damage

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7 January 2021

DNA base modifications and membrane damage in cultured mammalian cells treated with iron ions.

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7 January 2021

Formation of DNA-protein cross-links in cultured mammalian cells upon treatment with iron ions

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7 January 2021

Interaction of lipid peroxidation products with nuclear macromolecules

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7 January 2021

Detection of bulky DNA lesions in the liver of patients with Wilson's disease and primary haemochromatosis

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7 January 2021

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7 January 2021

Oxidative damage during aging targets mitochondrial aconitase

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7 January 2021

Mitochondrial adenine nucleotide translocase is modified oxidatively during aging

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7 January 2021

Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria

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7 January 2021

Hepatic mitochondrial energy production in rats with chronic iron overload

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7 January 2021

Mitochondrial respiratory enzymes are a major target of iron toxicity in rat heart cells

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7 January 2021

The participation of coenzyme Q in free radical production and antioxidation

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7 January 2021

Friedreich's ataxia: a clinical and genetic study of 90 families with an analysis of early diagnostic criteria and intrafamilial clustering of clinical features

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7 January 2021

Regulation of mitochondrial iron accumulation by Yfh1p, a putative homolog of frataxin

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7 January 2021

The yeast frataxin homologue mediates mitochondrial iron efflux. Evidence for a mitochondrial iron cycle

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7 January 2021

Aconitase and mitochondrial iron-sulphur protein deficiency in Friedreich ataxia

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7 January 2021

Marked increase in the number and variety of mitochondrial DNA rearrangements in aging human skeletal muscle

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7 January 2021

Deltoid human muscle mtDNA is extensively rearranged in old age subjects

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7 January 2021

Age-associated alterations of the mitochondrial genome

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7 January 2021

Mitochondrial DNA deletions in human cardiac tissue show a gross mosaic distribution

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7 January 2021

Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress

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7 January 2021

Preferential mitochondrial DNA injury caused by glucose oxidase as a steady generator of hydrogen peroxide in human fibroblasts

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7 January 2021

Normal oxidative damage to mitochondrial and nuclear DNA is extensive

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7 January 2021

Oxidative damage and mitochondrial decay in aging

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7 January 2021

Comparison of Oxidative Base Damage in Mitochondrial and Nuclear DNA

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7 January 2021

Quantification of oxidative DNA modifications in mitochondria.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900772-4

7 January 2021

Rapid evolution of animal mitochondrial DNA

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7 January 2021

Repair of mitochondrial DNA after various types of DNA damage in Chinese hamster ovary cells

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7 January 2021

Mitochondrial DNA sequence variation in human evolution and disease.

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7 January 2021

Mitochondrial diseases in man and mouse

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7 January 2021

Progressive hemochromatotic cardiomyopathy despite reversal of iron deposition after liver transplantation

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7 January 2021

A proposed refinement of the mitochondrial free radical theory of aging

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7 January 2021

Mitochondria harbouring mutant mtDNA--a cuckoo in the nest?

1 reference

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7 January 2021

A Ginkgo biloba extract (EGb 761) prevents mitochondrial aging by protecting against oxidative stress.

1 reference

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7 January 2021

Mitochondrial decay in hepatocytes from old rats: membrane potential declines, heterogeneity and oxidants increase

1 reference

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7 January 2021

Manganese superoxide dismutase protects mitochondrial complex I against adriamycin-induced cardiomyopathy in transgenic mice

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https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900772-4

7 January 2021

The effect of aging and an oxidative stress on peroxide levels and the mitochondrial membrane potential in isolated rat hepatocytes

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7 January 2021

Preferential oxidation of cardiac mitochondrial DNA following acute intoxication with doxorubicin

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7 January 2021

Oxidative stress, caloric restriction, and aging

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7 January 2021

Iron accumulation in aging: modulation by dietary restriction

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7 January 2021

Inhibition of iron absorption prolongs the life span of Drosophila.

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7 January 2021

Effects of diethyldithiocarbamate on life span, metabolic rate, superoxide dismutase, catalase, inorganic peroxides and glutathione in the adult male housefly, Musca domestica

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900772-4

7 January 2021

Lethal hydrogen peroxide toxicity involves lysosomal iron-catalyzed reactions with membrane damage

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900772-4

7 January 2021

Cellular injury induced by oxidative stress is mediated through lysosomal damage.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900772-4

7 January 2021

Endogenous ferritin protects cells with iron-laden lysosomes against oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900772-4

7 January 2021

Characterization of iron-mediated peroxidative injury in isolated hepatic lysosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900772-4

7 January 2021

Organelle pathology in primary and secondary haemochromatosis with special reference to lysosomal changes

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900772-4

7 January 2021

Liver cell damage and lysosomal iron storage in patients with idiopathic hemochromatosis. A light and electron microscopic study

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900772-4

7 January 2021

10.1016/S0891-5849(02)00772-4

Identifiers

DOI

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3 August 2017

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