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The Drosophila melanogaster sir2+ gene is nonessential and has only minor effects on position-effect variegation.
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Europe PubMed Central
PMC publication ID
1462486
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12663533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
title
The Drosophila melanogaster sir2+ gene is nonessential and has only minor effects on position-effect variegation
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
1462486
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12663533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
main subject
Drosophila melanogaster
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author
Stefan Åström
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
1462486
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12663533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
author name string
Thomas W Cline
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
1462486
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12663533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
Jasper Rine
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
1462486
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12663533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
language of work or name
English
0 references
publication date
1 March 2003
1 reference
stated in
Europe PubMed Central
PMC publication ID
1462486
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12663533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
published in
Genetics
1 reference
stated in
Europe PubMed Central
PMC publication ID
1462486
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12663533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
volume
163
1 reference
stated in
Europe PubMed Central
PMC publication ID
1462486
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12663533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
issue
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
1462486
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12663533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
page(s)
931-937
1 reference
stated in
Europe PubMed Central
PMC publication ID
1462486
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12663533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
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PubMed Central
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Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence
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PubMed Central
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The interaction of Alba, a conserved archaeal chromatin protein, with Sir2 and its regulation by acetylation
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PubMed Central
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Negative control of p53 by Sir2alpha promotes cell survival under stress
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dSIR2 and dHDAC6: two novel, inhibitor-resistant deacetylases in Drosophila melanogaster
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Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
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A cytosolic NAD-dependent deacetylase, Hst2p, can modulate nucleolar and telomeric silencing in yeast
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Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose
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Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae
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A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family.
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PubMed Central
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The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases
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PubMed Central
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Sir2 links chromatin silencing, metabolism, and aging
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PubMed Central
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7 July 2018
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
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PubMed Central
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7 July 2018
Sum1 and Hst1 repress middle sporulation-specific gene expression during mitosis in Saccharomyces cerevisiae
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PubMed Central
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7 July 2018
The Schizosaccharomyces pombe hst4(+) gene is a SIR2 homologue with silencing and centromeric functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462486
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7 July 2018
The Berkeley Drosophila Genome Project gene disruption project: Single P-element insertions mutating 25% of vital Drosophila genes.
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7 July 2018
Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity
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PubMed Central
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7 July 2018
Theme and variation among silencing proteins in Saccharomyces cerevisiae and Kluyveromyces lactis
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7 July 2018
Vive la différence: males vs females in flies vs worms
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462486
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7 July 2018
Transcriptional silencing in yeast is associated with reduced nucleosome acetylation
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PubMed Central
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7 July 2018
P-lacW insertional mutagenesis on the second chromosome of Drosophila melanogaster: isolation of lethals with different overgrowth phenotypes
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PubMed Central
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7 July 2018
Position-effect variegation and the new biology of heterochromatin
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PubMed Central
reference URL
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7 July 2018
The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability
1 reference
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PubMed Central
reference URL
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7 July 2018
Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae
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PubMed Central
reference URL
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7 July 2018
Functional cDNA libraries from Drosophila embryos
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PubMed Central
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7 July 2018
Cloning and characterization of four SIR genes of Saccharomyces cerevisiae
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PubMed Central
reference URL
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7 July 2018
Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae.
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PubMed Central
reference URL
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7 July 2018
Drosophila Sir2 is required for heterochromatic silencing and by euchromatic Hairy/E(Spl) bHLH repressors in segmentation and sex determination
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462486
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26 October 2018
Drosophila IRBP/Ku p70 corresponds to the mutagen-sensitive mus309 gene and is involved in P-element excision in vivo
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462486
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26 October 2018
Distinct roles of processes modulated by histone deacetylases Rpd3p, Hda1p, and Sir2p in life extension by caloric restriction in yeast
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12663533
retrieved
12 December 2020
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inferred from PubMed ID database lookup
Identifiers
PMC publication ID
1462486
1 reference
stated in
Europe PubMed Central
PMC publication ID
1462486
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12663533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
PubMed publication ID
12663533
1 reference
stated in
Europe PubMed Central
PMC publication ID
1462486
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12663533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
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