(Q34618459)

English

A Targeted Histone Acetyltransferase Can Create a Sizable Region of Hyperacetylated Chromatin and Counteract the Propagation of Transcriptionally Silent Chromatin

scientific article published on September 1, 2003

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scholarly article

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19 December 2019

A targeted histone acetyltransferase can create a sizable region of hyperacetylated chromatin and counteract the propagation of transcriptionally silent chromatin (English)

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19 December 2019

A Targeted Histone Acetyltransferase Can Create a Sizable Region of Hyperacetylated Chromatin and Counteract the Propagation of Transcriptionally Silent Chromatin (English)

1 reference

10.1093/GENETICS/165.1.115

https://api.crossref.org/works/10.1093/GENETICS/165.1.115

13 March 2024

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13 March 2024

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10.1093/GENETICS/165.1.115

https://api.crossref.org/works/10.1093/GENETICS/165.1.115

13 March 2024

author name string

Ya-Hui Chiu

1

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19 December 2019

Qun Yu

2

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19 December 2019

Xin Bi

4

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19 December 2019

Joseph J. Sandmeier

3

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13 March 2024

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1 September 2003

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19 December 2019

full work available at URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462738

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13 March 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/14504221/?tool=EBI

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13 March 2024

http://intl.genetics.org/cgi/content/abstract/165/1/115

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13 March 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/14504221/pdf/?tool=EBI

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13 March 2024

https://europepmc.org/articles/PMC1462738

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13 March 2024

https://europepmc.org/articles/PMC1462738?pdf=render

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13 March 2024

https://academic.oup.com/genetics/article-pdf/165/1/115/42052424/genetics0115.pdf

Portable Document Format

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10.1093/GENETICS/165.1.115

https://api.crossref.org/works/10.1093/GENETICS/165.1.115

13 March 2024

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19 December 2019

165

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19 December 2019

1

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19 December 2019

115-125

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19 December 2019

ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESIS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Sas4 and Sas5 are required for the histone acetyltransferase activity of Sas2 in the SAS complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Function and selectivity of bromodomains in anchoring chromatin-modifying complexes to promoter nucleosomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Cellular memory and the histone code

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Histone methyltransferase activity of a Drosophila Polycomb group repressor complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

RPD3 is required for the inactivation of yeast ribosomal DNA genes in stationary phase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Heritable chromatin structure: mapping "memory" in histones H3 and H4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Domains of gene silencing near the left end of chromosome III in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Braking the silence: how heterochromatic gene repression is stopped in its tracks.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Insulators: many functions, many mechanisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Histone acetylation beyond promoters: long-range acetylation patterns in the chromatin world

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Translating the Histone Code

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

The S. cerevisiae SAGA complex functions in vivo as a coactivator for transcriptional activation by Gal4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

SAGA is an essential in vivo target of the yeast acidic activator Gal4p

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Recruitment of HAT complexes by direct activator interactions with the ATM-related Tra1 subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Histone acetyltransferases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Transitions in histone acetylation reveal boundaries of three separately regulated neighboring loci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Chromosomal boundaries in S. cerevisiae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

RNA polymerase III and RNA polymerase II promoter complexes are heterochromatin barriers in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Global histone acetylation and deacetylation in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Distribution of acetylated histones resulting from Gal4-VP16 recruitment of SAGA and NuA4 complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

The yeast HML I silencer defines a heterochromatin domain boundary by directional establishment of silencing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

NuA4, an essential transcription adaptor/histone H4 acetyltransferase complex containing Esa1p and the ATM-related cofactor Tra1p

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Cell cycle-regulated histone acetylation required for expression of the yeast HO gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

UASrpg can function as a heterochromatin boundary element in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Esa1p is an essential histone acetyltransferase required for cell cycle progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Roles of histone acetyltransferases and deacetylases in gene regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Transcriptional activators direct histone acetyltransferase complexes to nucleosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Critical residues for histone acetylation by Gcn5, functioning in Ada and SAGA complexes, are also required for transcriptional function in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Histone acetyltransferase activity of yeast Gcn5p is required for the activation of target genes in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Hyperactivation of the silencing proteins, Sir2p and Sir3p, causes chromosome loss

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Histone acetyltransferase activity and interaction with ADA2 are critical for GCN5 function in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Spreading of transcriptional repressor SIR3 from telomeric heterochromatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Efficient transcriptional silencing in Saccharomyces cerevisiae requires a heterochromatin histone acetylation pattern

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Transcriptional silencing in yeast is associated with reduced nucleosome acetylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

LexA protein is a repressor of the colicin E1 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

5-Fluoroorotic acid as a selective agent in yeast molecular genetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

The HML mating-type cassette of Saccharomyces cerevisiae is regulated by two separate but functionally equivalent silencers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Multifunctional yeast high-copy-number shuttle vectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

7 July 2018

Structural and dynamic functions establish chromatin domains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

26 October 2018

Chromosomal gradient of histone acetylation established by Sas2p and Sir2p functions as a shield against gene silencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

26 October 2018

Sir2p and Sas2p opposingly regulate acetylation of yeast histone H4 lysine16 and spreading of heterochromatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

26 October 2018

Acetylation of the yeast histone H4 N terminus regulates its binding to heterochromatin protein SIR3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

26 October 2018

Correlation between histone lysine methylation and developmental changes at the chicken beta-globin locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

26 October 2018

Virus infection leads to localized hyperacetylation of histones H3 and H4 at the IFN-beta promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

26 October 2018

Mechanisms of silencing in Saccharomyces cerevisiae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462738

26 October 2018

Transcriptional and translational expression of a chimeric bacterial-yeast plasmid in yeasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/14504221

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a Ty insertion within the coding sequence of the S. cerevisiae URA3 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/14504221

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage

1 reference

https://pubmed.ncbi.nlm.nih.gov/14504221

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gcn4 activator targets Gcn5 histone acetyltransferase to specific promoters independently of transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/14504221

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Common themes in mechanisms of gene silencing

42

1 reference

10.1093/GENETICS/165.1.115

https://api.crossref.org/works/10.1093/GENETICS/165.1.115

13 March 2024

Loss of a yeast telomere: arrest, recovery, and chromosome loss.

48

1 reference

10.1093/GENETICS/165.1.115

https://api.crossref.org/works/10.1093/GENETICS/165.1.115

13 March 2024

Rap1p and other transcriptional regulators can function in defining distinct domains of gene expression

59

1 reference

10.1093/GENETICS/165.1.115

https://api.crossref.org/works/10.1093/GENETICS/165.1.115

13 March 2024

Identifiers

10.1093/GENETICS/165.1.115

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14504221

13 March 2024

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14504221%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14504221%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

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