(Q34618889)

3 August 2017

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title

Basic science review: Statin therapy--Part I: The pleiotropic effects of statins in cardiovascular disease (English)

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3 August 2017

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cardiovascular disease

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Benjamin Sadowitz

1

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3 August 2017

Kristopher G Maier

series ordinal

2

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3 August 2017

Vivian Gahtan

series ordinal

3

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3 August 2017

publication date

1 May 2010

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Vascular and Endovascular Surgery

3 August 2017

published in

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3 August 2017

volume

44

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3 August 2017

issue

4

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3 August 2017

page(s)

241-251

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Mevalonate pathway: a review of clinical and therapeutical implications

3 August 2017

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Effects of statins beyond lipid lowering: potential for clinical benefits.

21 January 2018

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Clinical implications for statin pleiotropy

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21 January 2018

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21 January 2018

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Anti-oxidative properties of fluvastatin, an HMG-CoA reductase inhibitor, contribute to prevention of atherosclerosis in cholesterol-fed rabbits

21 January 2018

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HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway

21 January 2018

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HMG-CoA reductase inhibitors reduce senescence and increase proliferation of endothelial progenitor cells via regulation of cell cycle regulatory genes

21 January 2018

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Statins enhance migratory capacity by upregulation of the telomere repeat-binding factor TRF2 in endothelial progenitor cells.

21 January 2018

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HMG-CoA reductase inhibitor mobilizes bone marrow--derived endothelial progenitor cells

21 January 2018

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Simvastatin inhibits human saphenous vein neointima formation via inhibition of smooth muscle cell proliferation and migration

21 January 2018

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Induction of apoptosis and inhibition of migration of inflammatory and vascular wall cells by cerivastatin

21 January 2018

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HMG-CoA reductase inhibitors induce apoptosis in neointima-derived vascular smooth muscle cells

21 January 2018

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Statins suppress oxidized low density lipoprotein-induced macrophage proliferation by inactivation of the small G protein-p38 MAPK pathway

21 January 2018

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An HMG-CoA reductase inhibitor, cerivastatin, suppresses growth of macrophages expressing matrix metalloproteinases and tissue factor in vivo and in vitro

21 January 2018

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Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilization

21 January 2018

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The expression of the lectin-like oxidized low-density lipoprotein receptor (LOX-1) on human vascular smooth muscle cells and monocytes and its down-regulation by lovastatin

21 January 2018

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Lovastatin inhibits gene expression of type-I scavenger receptor in THP-1 human macrophages

21 January 2018

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Rapid reduction in C-reactive protein with cerivastatin among 785 patients with primary hypercholesterolemia

21 January 2018

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Measurement of C-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary events

21 January 2018

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Statins and cancer: A systematic review and meta-analysis

21 January 2018

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Statins for infection and sepsis: a systematic review of the clinical evidence

21 January 2018

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Novel therapeutic options for osteoporosis

21 January 2018

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Pleiotropic effects of statins

21 January 2018

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The pleiotropic effects of statins.

21 January 2018

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Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors

21 January 2018

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Chemical, pharmacokinetic and pharmacodynamic properties of statins: an update

21 January 2018

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Preclinical and clinical pharmacology of Rosuvastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor

21 January 2018

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Pravastatin. A review of its pharmacological properties and therapeutic potential in hypercholesterolaemia

21 January 2018

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Uptake of rosuvastatin by isolated rat hepatocytes: comparison with pravastatin

21 January 2018

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Antiatherothrombotic properties of statins: implications for cardiovascular event reduction

21 January 2018

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Hydrophilicity/lipophilicity: relevance for the pharmacology and clinical effects of HMG-CoA reductase inhibitors

21 January 2018

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21 January 2018

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Atherosclerosis — An Inflammatory Disease

21 January 2018

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Platelets in atherothrombosis

21 January 2018

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Platelet lipoprotein interplay: trigger of foam cell formation and driver of atherosclerosis

21 January 2018

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Integrin alpha(v)beta(3) as a target in the prevention of neointimal hyperplasia

21 January 2018

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Endothelin and restenosis

21 January 2018

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Incidence of restenosis after successful coronary angioplasty: a time-related phenomenon. A quantitative angiographic study in 342 consecutive patients at 1, 2, 3, and 4 months

21 January 2018

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The restenosis paradigm revisited: an alternative proposal for cellular mechanisms

21 January 2018

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Regulation of the mevalonate pathway

21 January 2018

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HMG-CoA reductase inhibitors and the malignant cell: the statin family of drugs as triggers of tumor-specific apoptosis

21 January 2018

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Cerivastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a reductase, inhibits endothelial cell proliferation induced by angiogenic factors in vitro and angiogenesis in in vivo models

21 January 2018

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Regulation of macrophage cholesterol efflux through hydroxymethylglutaryl-CoA reductase inhibition: a role for RhoA in ABCA1-mediated cholesterol efflux

21 January 2018

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Protein lipidation in cell signaling

21 January 2018

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Small GTP-binding proteins and mitogen-activated protein kinases as promising therapeutic targets of vascular remodeling

21 January 2018

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Farnesyltransferase inhibitor, manumycin a, prevents atherosclerosis development and reduces oxidative stress in apolipoprotein E-deficient mice.

21 January 2018

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Effects of active and negative mutants of Ras on rat arterial neointima formation

21 January 2018

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Rho GTPases and signaling networks

21 January 2018

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Thrombin suppresses endothelial nitric oxide synthase and upregulates endothelin-converting enzyme-1 expression by distinct pathways: role of Rho/ROCK and mitogen-activated protein kinase

21 January 2018

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Platelet hypersensitivity induced by cholesterol incorporation

21 January 2018

1 reference

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Low-density lipoprotein and its effect on human blood platelets

21 January 2018

1 reference

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Oxidation of LDL and its clinical implication

21 January 2018

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Lewis A. Conner Memorial Lecture. Oxidative modification of LDL and atherogenesis

21 January 2018

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Oxidatively modified low density lipoproteins: a potential role in recruitment and retention of monocyte/macrophages during atherogenesis

21 January 2018

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Oxidatively modified low density lipoprotein is a chemoattractant for human T lymphocytes

21 January 2018

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Statins inhibit oxidized-LDL-mediated LOX-1 expression, uptake of oxidized-LDL and reduction in PKB phosphorylation

21 January 2018

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Cells in focus: endothelial cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574410362922

The nonlipid effects of statins on endothelial function

21 January 2018

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The effects of HMG-CoA reductase inhibitors on endothelial function

21 January 2018

1 reference

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The L-arginine-nitric oxide pathway

21 January 2018

1 reference

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Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells

21 January 2018

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An L-arginine/nitric oxide pathway present in human platelets regulates aggregation

21 January 2018

1 reference

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Enhanced endothelial adhesiveness in hypercholesterolemia is attenuated by L-arginine

21 January 2018

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Evidence for enhanced vascular superoxide anion production in nitrate tolerance. A novel mechanism underlying tolerance and cross-tolerance

21 January 2018

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Cellular and molecular mechanisms of endothelial cell dysfunction

21 January 2018

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Molecular bases of the acute coronary syndromes

21 January 2018

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CD40-CD40L interactions in atherosclerosis

21 January 2018

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Reduction of atherosclerosis in mice by inhibition of CD40 signalling

21 January 2018

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Statins (HMG-CoA reductase inhibitors) reduce CD40 expression in human vascular cells

21 January 2018

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Prognostic value of high-sensitivity C-reactive protein in heart failure: a systematic review.

21 January 2018

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Mechanisms of plaque vulnerability and rupture

21 January 2018

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https://api.crossref.org/works/10.1177%2F1538574410362922

Effects of statins on vascular wall: vasomotor function, inflammation, and plaque stability

21 January 2018

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Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574410362922

Lipid lowering by diet reduces matrix metalloproteinase activity and increases collagen content of rabbit atheroma: a potential mechanism of lesion stabilization.

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1177/1538574410362922

1 reference

release_hsf6mojk7fdddhiyvvmeq3ld4i

3 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/hsf6mojk7fdddhiyvvmeq3ld4i

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference