(Q34623781)

3 August 2017

title

A minimal Rac activation domain in the unconventional guanine nucleotide exchange factor Dock180. (English)

1 reference

3 August 2017

Xin Wu

1

1 reference

3 August 2017

Sekar Ramachandran

2

1 reference

3 August 2017

Miao-Chong J Lin

3

1 reference

3 August 2017

Richard A Cerione

4

1 reference

3 August 2017

Jon W Erickson

5

1 reference

3 August 2017

language of work or name

English

0 references

publication date

20 January 2011

1 reference

3 August 2017

1 reference

3 August 2017

volume

50

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3 August 2017

issue

6

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3 August 2017

page(s)

1070-1080

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GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

3 August 2017

cites work

1 reference

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Activation of Rho GTPases by DOCK exchange factors is mediated by a nucleotide sensor

7 July 2018

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New insights into how the Rho guanine nucleotide dissociation inhibitor regulates the interaction of Cdc42 with membranes

7 July 2018

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7 July 2018

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Specific recognition of Rac2 and Cdc42 by DOCK2 and DOCK9 guanine nucleotide exchange factors

7 July 2018

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BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module

7 July 2018

1 reference

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GEF what? Dock180 and related proteins help Rac to polarize cells in new ways

7 July 2018

1 reference

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PIC: Protein Interactions Calculator

7 July 2018

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Dock6, a Dock-C subfamily guanine nucleotide exchanger, has the dual specificity for Rac1 and Cdc42 and regulates neurite outgrowth

7 July 2018

1 reference

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The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

7 July 2018

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The DOCK180/Elmo complex couples ARNO-mediated Arf6 activation to the downstream activation of Rac1.

7 July 2018

1 reference

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A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling

7 July 2018

1 reference

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A Steric-inhibition model for regulation of nucleotide exchange via the Dock180 family of GEFs

7 July 2018

1 reference

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The Cool-2/alpha-Pix protein mediates a Cdc42-Rac signaling cascade

7 July 2018

1 reference

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Engulfment: ingestion and migration with Rac, Rho and TRIO

7 July 2018

1 reference

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Novel regulatory mechanisms for the Dbl family guanine nucleotide exchange factor Cool-2/alpha-Pix

7 July 2018

1 reference

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PH domain of ELMO functions in trans to regulate Rac activation via Dock180

7 July 2018

1 reference

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Cdc42: new roads to travel

7 July 2018

1 reference

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Structural elements, mechanism, and evolutionary convergence of Rho protein-guanine nucleotide exchange factor complexes

7 July 2018

1 reference

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MOCA induces membrane spreading by activating Rac1.

7 July 2018

1 reference

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Cell corpse engulfment mediated by C. elegans phosphatidylserine receptor through CED-5 and CED-12

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048587

Dock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048587

Role of Rho-family proteins in cell adhesion and cancer.

7 July 2018

1 reference

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DOCK4, a GTPase activator, is disrupted during tumorigenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048587

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048587

Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048587

Signaling to the Rho GTPases: networking with the DH domain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048587

Regulation of the Cool/Pix proteins: key binding partners of the Cdc42/Rac targets, the p21-activated kinases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048587

C. elegans CED-12 acts in the conserved crkII/DOCK180/Rac pathway to control cell migration and cell corpse engulfment.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048587

Molecular basis for Rac1 recognition by guanine nucleotide exchange factors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048587

Trp(56) of rac1 specifies interaction with a subset of guanine nucleotide exchange factors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048587

CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048587

Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048587

Automated analysis of interatomic contacts in proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048587

Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048587

A novel regulator of p21-activated kinases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048587

C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048587

Rho, Rac and Cdc42 GTPases regulate the organization of the actin cytoskeleton

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048587

Chromosomal mapping of the gene encoding DOCK180, a major Crk-binding protein, to 10q26.13-q26.3 by fluorescence in situ hybridization

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048587

DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048587

Identification of the protein encoded by the human diffuse B-cell lymphoma (dbl) oncogene

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048587

The ras superfamily proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048587

Expression of epidermal growth factor receptor sequences as E. coli fusion proteins: applications in the study of tyrosine kinase function.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048587

Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048587

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048587

The RhoA- and CDC42-specific exchange factor Dbs promotes expansion of immature thymocytes and deletion of double-positive and single-positive thymocytes.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048587

Crystal Structure of the DH/PH Fragment of Dbs without Bound GTPase

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048587

9 December 2018

Identifiers

DOI

10.1021/BI100971Y

1 reference

3 August 2017

1 reference

3 August 2017

1 reference