(Q34626870)

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Inhibition of nonsense-mediated mRNA decay by antisense morpholino oligonucleotides restores functional expression of hERG nonsense and frameshift mutations in long-QT syndrome

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Inhibition of nonsense-mediated mRNA decay by antisense morpholino oligonucleotides restores functional expression of hERG nonsense and frameshift mutations in long-QT syndrome (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

author name string

Qiuming Gong

1

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Matthew R Stump

2

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Zhengfeng Zhou

3

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

publication date

28 October 2010

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Journal of Molecular and Cellular Cardiology

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

50

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

223-229

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Genotype-phenotype aspects of type 2 long QT syndrome

1 reference

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RNA-targeting approaches for neuromuscular diseases

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Introducing sense into nonsense in treatments of human genetic diseases

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The meaning of nonsense

1 reference

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Recurrent intrauterine fetal loss due to near absence of HERG: clinical and functional characterization of a homozygous nonsense HERG Q1070X mutation

1 reference

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A splice site mutation in hERG leads to cryptic splicing in human long QT syndrome

1 reference

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Nonsense mutations in hERG cause a decrease in mutant mRNA transcripts by nonsense-mediated mRNA decay in human long-QT syndrome

1 reference

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Spectrum of pathogenic mutations and associated polymorphisms in a cohort of 44 unrelated patients with long QT syndrome

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Applying nonsense-mediated mRNA decay research to the clinic: progress and challenges

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Nonsense-mediated mRNA decay modulates clinical outcome of genetic disease

1 reference

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Nonsense-mediated mRNA decay: molecular insights and mechanistic variations across species

1 reference

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Nonsense-mediated decay approaches the clinic

1 reference

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Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPS1

1 reference

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The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions

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Spectrum of mutations in long-QT syndrome genes. KVLQT1, HERG, SCN5A, KCNE1, and KCNE2

1 reference

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Correction of aberrant splicing of the cystic fibrosis transmembrane conductance regulator (CFTR) gene by antisense oligonucleotides

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Nonsense-mediated mRNA decay in health and disease

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At least one intron is required for the nonsense-mediated decay of triosephosphate isomerase mRNA: a possible link between nuclear splicing and cytoplasmic translation

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HERG channel dysfunction in human long QT syndrome. Intracellular transport and functional defects

1 reference

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A rule for termination-codon position within intron-containing genes: when nonsense affects RNA abundance

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Properties of HERG channels stably expressed in HEK 293 cells studied at physiological temperature

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Restoration of correct splicing in thalassemic pre-mRNA by antisense oligonucleotides

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Identifiers

10.1016/J.YJMCC.2010.10.022

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

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