(Q34627033)

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Myogenic Akt signaling attenuates muscular degeneration, promotes myofiber regeneration and improves muscle function in dystrophin-deficient mdx mice

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Myogenic Akt signaling attenuates muscular degeneration, promotes myofiber regeneration and improves muscle function in dystrophin-deficient mdx mice (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

author name string

Michelle H Kim

1

1 reference

Europe PubMed Central

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3 August 2017

Danielle I Kay

2

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3 August 2017

Renuka T Rudra

3

1 reference

Europe PubMed Central

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3 August 2017

Bo Ming Chen

4

1 reference

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3 August 2017

Nigel Hsu

5

1 reference

Europe PubMed Central

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3 August 2017

Yasuhiro Izumiya

6

1 reference

Europe PubMed Central

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3 August 2017

Leonel Martinez

7

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Melissa J Spencer

8

1 reference

Europe PubMed Central

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3 August 2017

Kenneth Walsh

9

1 reference

Europe PubMed Central

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3 August 2017

Alan D Grinnell

10

1 reference

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3 August 2017

Rachelle H Crosbie

11

1 reference

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3 August 2017

publication date

18 January 2011

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Europe PubMed Central

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3 August 2017

Human Molecular Genetics

1 reference

Europe PubMed Central

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3 August 2017

20

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

1324-1338

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Sarcolemmal nNOS anchoring reveals a qualitative difference between dystrophin and utrophin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Making fast-twitch dystrophic muscles bigger protects them from contraction injury and attenuates the dystrophic pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Inducible activation of Akt increases skeletal muscle mass and force without satellite cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Targeting the phosphoinositide 3-kinase pathway in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Dystrophins carrying spectrin-like repeats 16 and 17 anchor nNOS to the sarcolemma and enhance exercise performance in a mouse model of muscular dystrophy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Distinct actions of Akt1 and Akt2 in skeletal muscle differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Myogenic Akt signaling upregulates the utrophin-glycoprotein complex and promotes sarcolemma stability in muscular dystrophy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Follistatin-like 1, a secreted muscle protein, promotes endothelial cell function and revascularization in ischemic tissue through a nitric-oxide synthase-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Fast/Glycolytic muscle fiber growth reduces fat mass and improves metabolic parameters in obese mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Increasing alpha 7 beta 1-integrin promotes muscle cell proliferation, adhesion, and resistance to apoptosis without changing gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Conditional mouse models to study developmental and pathophysiological gene function in muscle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Pathophysiology of duchenne muscular dystrophy: current hypotheses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Transgenic expression of {alpha}7{beta}1 integrin maintains muscle integrity, increases regenerative capacity, promotes hypertrophy, and reduces cardiomyopathy in dystrophic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Myotoxic phospholipases A2 and the regeneration of skeletal muscles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Tetracycline-inducible system for regulation of skeletal muscle-specific gene expression in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Vasomodulation by skeletal muscle-derived nitric oxide requires alpha-syntrophin-mediated sarcolemmal localization of neuronal Nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

A protein kinase B-dependent and rapamycin-sensitive pathway controls skeletal muscle growth but not fiber type specification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Myogenic Akt signaling regulates blood vessel recruitment during myofiber growth.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Muscle-specific expression of insulin-like growth factor I counters muscle decline in mdx mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

The dystrophin-glycoprotein complex, cellular signaling, and the regulation of cell survival in the muscular dystrophies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

A nitric oxide synthase transgene ameliorates muscular dystrophy in mdx mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Enhanced expression of the alpha 7 beta 1 integrin reduces muscular dystrophy and restores viability in dystrophic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Functional muscle ischemia in neuronal nitric oxide synthase-deficient skeletal muscle of children with Duchenne muscular dystrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Cellular survival: a play in three Akts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Muscle degeneration without mechanical injury in sarcoglycan deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Secondary reduction of alpha7B integrin in laminin alpha2 deficient congenital muscular dystrophy supports an additional transmembrane link in skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

The alpha7beta1 integrin in muscle development and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Expression of full-length utrophin prevents muscular dystrophy in mdx mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Gamma-sarcoglycan deficiency leads to muscle membrane defects and apoptosis independent of dystrophin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Effect of propylthiouracil-induced hypothyroidism on the onset of skeletal muscle necrosis in dystrophin-deficient mdx mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Altered expression of the alpha7beta1 integrin in human and murine muscular dystrophies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Integrins (alpha7beta1) in muscle function and survival. Disrupted expression in merosin-deficient congenital muscular dystrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

The mdx-amplification-resistant mutation system assay, a simple and rapid polymerase chain reaction-based detection of the mdx allele

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Utrophin: a structural and functional comparison to dystrophin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Expression of caveolin-3 in skeletal, cardiac, and smooth muscle cells. Caveolin-3 is a component of the sarcolemma and co-fractionates with dystrophin and dystrophin-associated glycoproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Dystrophin protects the sarcolemma from stresses developed during muscle contraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

A role for the dystrophin-glycoprotein complex as a transmembrane linker between laminin and actin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

SH3 domain-mediated interaction of dystroglycan and Grb2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

X chromosome-linked muscular dystrophy (mdx) in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Muscular dystrophy in the mdx mouse: histopathology of the soleus and extensor digitorum longus muscles.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Fast muscle fibers are preferentially affected in Duchenne muscular dystrophy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Dystrophin: the protein product of the Duchenne muscular dystrophy locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Increased protein degradation results from elevated free calcium levels found in muscle from mdx mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Association of dystrophin and an integral membrane glycoprotein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Glycoprotein complex anchoring dystrophin to sarcolemma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Purification of dystrophin from skeletal muscle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Fiber regeneration is not persistent in dystrophic (MDX) mouse skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Membrane organization of the dystrophin-glycoprotein complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Immunolocalization and developmental expression of dystrophin related protein in skeletal muscle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Dystrophin-associated proteins are greatly reduced in skeletal muscle from mdx mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Association of dystrophin-related protein with dystrophin-associated proteins in mdx mouse muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049356

7 July 2018

Hypertrophic response of Duchenne and limb-girdle muscular dystrophies is associated with activation of Akt pathway

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR015

21 January 2018

Dystrophin-related protein, utrophin, in normal and dystrophic human fetal skeletal muscle

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR015

21 January 2018

Utrophin may be a precursor of dystrophin during skeletal muscle development.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR015

21 January 2018

Akt activation prevents the force drop induced by eccentric contractions in dystrophin-deficient skeletal muscle

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR015

21 January 2018

Autocrine growth factor signaling by insulin-like growth factor-II mediates MyoD-stimulated myocyte maturation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR015

21 January 2018

Over-expression of Microspan, a novel component of the sarcoplasmic reticulum, causes severe muscle pathology with triad abnormalities

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR015

21 January 2018

Deficiency of a glycoprotein component of the dystrophin complex in dystrophic muscle

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR015

21 January 2018

Amelioration of the dystrophic phenotype of mdx mice using a truncated utrophin transgene

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR015

21 January 2018

Impact of sarcoglycan complex on mechanical signal transduction in murine skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/21245083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of IGF-binding protein-5 in Duchenne muscular dystrophy (DMD) fibroblasts correlates with the fibroblast-induced downregulation of DMD myoblast growth: an in vitro analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21245083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of myostatin attenuates severity of muscular dystrophy in mdx mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21245083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mutant mdx: inherited myopathy in the mouse. Morphological studies of nerves, muscles and end-plates

1 reference

https://pubmed.ncbi.nlm.nih.gov/21245083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Severe muscular dystrophy in mice that lack dystrophin and alpha7 integrin

1 reference

https://pubmed.ncbi.nlm.nih.gov/21245083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-7 is expressed and secreted by human skeletal muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21245083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mdx mouse skeletal muscle myopathy: I. A histological, morphometric and biochemical investigation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21245083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Focal adhesion kinase in integrin-mediated signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/21245083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/HMG/DDR015

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

ResearchGate publication ID

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