(Q34627899)

3 August 2017

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title

Characteristics and common properties of inhibitors, inducers, and activators of CYP enzymes (English)

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3 August 2017

Paul F Hollenberg

1

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3 August 2017

language of work or name

English

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publication date

1 February 2002

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3 August 2017

published in

Drug Metabolism Reviews

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3 August 2017

volume

34

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3 August 2017

issue

1-2

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3 August 2017

page(s)

17-35

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Death attributed to the toxic interaction of triazolam, amitriptyline and other psychotropic drugs

3 August 2017

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Selective inhibitory interactions of alkoxymethylenedioxybenzenes towards mono-oxygenase activity in rat-hepatic microsomes.

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Mechanism-based inactivators as probes of cytochrome P450 structure and function

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Inactivation of cytochrome P450 3A4 by bergamottin, a component of grapefruit juice

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Suicide substrates for the alanine racemase of Escherichia coli B

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A genetic analysis of processes regulating cytochrome P4501A1 expression

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Partial characterization of the human CYP1A1 negatively acting transcription factor and mutational analysis of its cognate DNA recognition sequence

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Regulation of cytochrome P450 (CYP) genes by nuclear receptors.

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Evidence for increased translational efficiency in the induction of P450IIE1 by solvents: analysis of P450IIE1 mRNA polyribosomal distribution

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Induction of P4502E1 by acetone in isolated rabbit hepatocytes. Role of increased protein and mRNA synthesis.

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Characterization of cytochrome P450 2E1 induction in a rat hepatoma FGC-4 cell model by ethanol

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The increase in urinary excretion of 6 beta-hydroxycortisol as a marker of human hepatic cytochrome P450IIIA induction

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Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes

21 January 2018

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Gut wall metabolism of verapamil in older people: effects of rifampicin-mediated enzyme induction

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Rifampin drastically reduces plasma concentrations and effects of oral midazolam.

21 January 2018

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Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction

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The role of the stimulation of ANDPH-cytochrome P-450 reductase activity in hepatic, microsomal mixed function oxidase activity

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Heterotropic cooperativity of cytochrome P450 3A4 and potential drug-drug interactions

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Analysis of human cytochrome P450 3A4 cooperativity: construction and characterization of a site-directed mutant that displays hyperbolic steroid hydroxylation kinetics

21 January 2018

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Inhibition and induction of cytochrome P450 and the clinical implications

21 January 2018

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Virtual kinetics: using statistical experimental design for rapid analysis of enzyme inhibitor mechanisms

21 January 2018

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Oxidation-reduction properties of rat liver cytochromes P-450 and NADPH-cytochrome P-450 reductase related to catalysis in reconstituted systems

21 January 2018

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The enzymic formation of methylenedioxyphenyl derivative exhibiting an isocyanide-like spectrum with reduced cytochrome P-450 in hepatic microsomes

21 January 2018

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Nitrosoalkanes as Fe(II) ligands in the 455-nm-absorbing cytochrome P-450 complexes formed from nitroalkanes in reducing conditions

21 January 2018

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Acetone enhancement of microsomal aniline para-hydroxylase activity

21 January 2018

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Oxidation of benzo[a]pyrene by recombinant human cytochrome P450 enzymes

21 January 2018

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Evaluation of atypical cytochrome P450 kinetics with two-substrate models: evidence that multiple substrates can simultaneously bind to cytochrome P450 active sites

21 January 2018

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Allosteric behavior in cytochrome p450-dependent in vitro drug-drug interactions: a prospective based on conformational dynamics

21 January 2018

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21 January 2018

Identifiers

DOI

10.1081/DMR-120001387

1 reference

3 August 2017

1 reference