(Q34632017)

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Ginsenoside Rg1 decreases Aβ(1-42) level by upregulating PPARγ and IDE expression in the hippocampus of a rat model of Alzheimer's disease

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Ginsenoside Rg1 decreases Aβ(1-42) level by upregulating PPARγ and IDE expression in the hippocampus of a rat model of Alzheimer's disease (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Alzheimer's disease

0 references

ginsenoside Rg1

1 reference

ChEBI release 2020-05-28

author name string

QianKun Quan

1

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Jue Wang

2

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Xi Li

3

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Yi Wang

4

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

language of work or name

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publication date

8 March 2013

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

e59155

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

copyright license

Creative Commons Attribution 4.0 International

8 March 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

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describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3592813/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Multi-faced neuroprotective effects of Ginsenoside Rg1 in an Alzheimer mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592813

7 July 2018

Risk of bladder cancer among diabetic patients treated with pioglitazone: interim report of a longitudinal cohort study.

1 reference

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7 July 2018

Paeonol increases levels of cortical cytochrome oxidase and vascular actin and improves behavior in a rat model of Alzheimer's disease

1 reference

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7 July 2018

ACP Journal Club. In older patients, rosiglitazone was associated with increased risk for stroke, heart failure, and mortality compared with pioglitazone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592813

7 July 2018

Ginsenoside Rg1 protects against hydrogen peroxide-induced cell death in PC12 cells via inhibiting NF-κB activation

1 reference

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Rosiglitazone rescues memory impairment in Alzheimer's transgenic mice: mechanisms involving a reduced amyloid and tau pathology

1 reference

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Insulin-degrading enzyme sorting in exosomes: a secretory pathway for a key brain amyloid-beta degrading protease

1 reference

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Insulin-degrading enzyme: structure-function relationship and its possible roles in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592813

7 July 2018

PPARgamma transcriptionally regulates the expression of insulin-degrading enzyme in primary neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592813

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Clearance of amyloid-beta peptide across the blood-brain barrier: implication for therapies in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592813

7 July 2018

Differential cerebral deposition of IDE and NEP in sporadic and familial Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592813

7 July 2018

Rosiglitazone evaluated for cardiovascular outcomes--an interim analysis

1 reference

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7 July 2018

Matrix metalloproteinase-9 degrades amyloid-beta fibrils in vitro and compact plaques in situ

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592813

7 July 2018

Insulin, insulin-degrading enzyme and amyloid-beta peptide in Alzheimer's disease: review and hypothesis.

1 reference

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7 July 2018

Chemokine receptor 5 antagonist D-Ala-peptide T-amide reduces microglia and astrocyte activation within the hippocampus in a neuroinflammatory rat model of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592813

7 July 2018

Anti-amnestic and anti-aging effects of ginsenoside Rg1 and Rb1 and its mechanism of action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592813

7 July 2018

Clearance of Alzheimer's Abeta peptide: the many roads to perdition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592813

7 July 2018

Clearing amyloid through the blood-brain barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592813

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Prospective study of type 2 diabetes and cognitive decline in women aged 70-81 years

1 reference

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7 July 2018

Neprilysin gene transfer reduces human amyloid pathology in transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592813

7 July 2018

Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592813

7 July 2018

Reduced hippocampal insulin-degrading enzyme in late-onset Alzheimer's disease is associated with the apolipoprotein E-epsilon4 allele

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592813

7 July 2018

The role of insulin resistance in the pathogenesis of Alzheimer's disease: implications for treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592813

7 July 2018

Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592813

7 July 2018

Angiotensin-converting enzyme degrades Alzheimer amyloid beta-peptide (A beta ); retards A beta aggregation, deposition, fibril formation; and inhibits cytotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592813

7 July 2018

Degradation of the Alzheimer's amyloid beta peptide by endothelin-converting enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592813

7 July 2018

Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592813

7 July 2018

Ginsenoside Rb1 and Rg1 improve spatial learning and increase hippocampal synaptophysin level in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592813

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Cognition and synaptic plasticity in diabetes mellitus

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7 July 2018

Ginseng pharmacology: multiple constituents and multiple actions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592813

7 July 2018

Insulin-degrading enzyme: embarking on amyloid destruction.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0059155

21 January 2018

Neprilysin and insulin-degrading enzyme levels are increased in Alzheimer disease in relation to disease severity.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0059155

21 January 2018

Ginsenoside Rg1 inhibits beta-secretase activity in vitro and protects against Abeta-induced cytotoxicity in PC12 cells

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0059155

21 January 2018

Ginsenoside Rg1 attenuates amyloid-beta content, regulates PKA/CREB activity, and improves cognitive performance in SAMP8 mice

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0059155

21 January 2018

The study of ginsenoside on PPARgamma expression of mononuclear macrophage in type 2 diabetes

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0059155

21 January 2018

Genistein ameliorates learning and memory deficits in amyloid β(1-40) rat model of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0059155

21 January 2018

Effects of ginsenosides on maze performance and brain choline acetyltransferase activity in scopolamine-treated young rats and aged rats.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0059155

21 January 2018

Intramuscular delivery of a single chain antibody gene prevents brain Aβ deposition and cognitive impairment in a mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0059155

21 January 2018

Fasting insulin and incident dementia in an elderly population of Japanese-American men.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0059155

21 January 2018

Immunohistochemical distribution of the receptor for advanced glycation end products in neurons and astrocytes in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0059155

21 January 2018

Insulin increases CSF Abeta42 levels in normal older adults

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0059155

21 January 2018

Rosiglitazone and pioglitazone increase fracture risk in women and men with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0059155

21 January 2018

Insulin degrading enzyme activity selectively decreases in the hippocampal formation of cases at high risk to develop Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0059155

21 January 2018

Degradation of soluble amyloid beta-peptides 1-40, 1-42, and the Dutch variant 1-40Q by insulin degrading enzyme from Alzheimer disease and control brains.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0059155

21 January 2018

Increased expression of Abeta degrading enzyme IDE in the cortex of transgenic mice with Alzheimer's disease-like neuropathology.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0059155

21 January 2018

Colchicines-induced neurotoxicity as an animal model of sporadic dementia of Alzheimer's type

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592813

26 October 2018

Telmisartan, a dual ARB/partial PPAR-γ agonist, protects myocardium from ischaemic reperfusion injury in experimental diabetes

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0059155

21 January 2018

Effect of pioglitazone on altered expression of Aβ metabolism-associated molecules in the brain of fructose-drinking rats, a rodent model of insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/23520555

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ginsenoside Rg1 protects primary cultured rat hippocampal neurons from cell apoptosis induced by β-amyloid protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/23520555

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The plasmin system is induced by and degrades amyloid-beta aggregates

1 reference

https://pubmed.ncbi.nlm.nih.gov/23520555

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasmin cleavage of the amyloid beta-protein: alteration of secondary structure and stimulation of tissue plasminogen activator activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/23520555

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0059155

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

2013PLoSO...859155Q

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

ResearchGate publication ID

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