(Q34632044)

English

Structural basis on the dityrosyl-diiron radical cluster and the functional differences of human ribonucleotide reductase small subunits hp53R2 and hRRM2.

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

Structural basis on the dityrosyl-diiron radical cluster and the functional differences of human ribonucleotide reductase small subunits hp53R2 and hRRM2. (English)

1 reference

Europe PubMed Central

3 August 2017

1 reference

ORCID Public Data File 2021

author name string

Bingsen Zhou

1

1 reference

Europe PubMed Central

3 August 2017

Leila Su

2

1 reference

Europe PubMed Central

3 August 2017

Yate-Ching Yuan

3

1 reference

Europe PubMed Central

3 August 2017

Frank Un

4

1 reference

Europe PubMed Central

3 August 2017

Norby Wang

5

1 reference

Europe PubMed Central

3 August 2017

Madhukar Patel

6

1 reference

Europe PubMed Central

3 August 2017

Bixin Xi

7

1 reference

Europe PubMed Central

3 August 2017

Shuya Hu

8

1 reference

Europe PubMed Central

3 August 2017

Yun Yen

9

1 reference

Europe PubMed Central

3 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

18 May 2010

1 reference

Europe PubMed Central

3 August 2017

Molecular Cancer Therapeutics

1 reference

Europe PubMed Central

3 August 2017

9

1 reference

Europe PubMed Central

3 August 2017

6

1 reference

Europe PubMed Central

3 August 2017

1669-1679

1 reference

Europe PubMed Central

3 August 2017

2.6 Å X-ray Crystal Structure of Human p53R2, a p53-Inducible Ribonucleotide Reductase,

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

7 July 2018

Regulation of p53R2 and its role as potential target for cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

7 July 2018

Ribonucleotide reductase: a critical enzyme for cancer chemotherapy and antiviral agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

7 July 2018

Using circular dichroism spectra to estimate protein secondary structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

7 July 2018

Ribonucleotide reductase subunits M2 and p53R2 are potential biomarkers for metastasis of colon cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

7 July 2018

Metastasis-suppressing potential of ribonucleotide reductase small subunit p53R2 in human cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

7 July 2018

Ribonucleotide reductases: influence of environment on synthesis and activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

7 July 2018

A dityrosyl-diiron radical cofactor center is essential for human ribonucleotide reductases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

7 July 2018

Structure and interactions of amino acid radicals in class I ribonucleotide reductase studied by ENDOR and high-field EPR spectroscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

7 July 2018

A new tyrosyl radical on Phe208 as ligand to the diiron center in Escherichia coli ribonucleotide reductase, mutant R2-Y122H. Combined x-ray diffraction and EPR/ENDOR studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

7 July 2018

Structural and mutational studies of the carboxylate cluster in iron-free ribonucleotide reductase R2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

7 July 2018

Structure, function, and mechanism of ribonucleotide reductases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

7 July 2018

In vitro characterization of enzymatic properties and inhibition of the p53R2 subunit of human ribonucleotide reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

7 July 2018

Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

7 July 2018

Radical initiation in the class I ribonucleotide reductase: long-range proton-coupled electron transfer?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

7 July 2018

In vivo assay for low-activity mutant forms of Escherichia coli ribonucleotide reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

7 July 2018

Structure and function of the radical enzyme ribonucleotide reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

7 July 2018

Mammalian p53R2 protein forms an active ribonucleotide reductase in vitro with the R1 protein, which is expressed both in resting cells in response to DNA damage and in proliferating cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

7 July 2018

High-frequency (140-GHz) time domain EPR and ENDOR spectroscopy: the tyrosyl radical-diiron cofactor in ribonucleotide reductase from yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

7 July 2018

A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

7 July 2018

The three-dimensional structure of mammalian ribonucleotide reductase protein R2 reveals a more-accessible iron-radical site than Escherichia coli R2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

7 July 2018

Tryptophan radicals formed by iron/oxygen reaction with Escherichia coli ribonucleotide reductase protein R2 mutant Y122F.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

7 July 2018

Structure of ribonucleotide reductase protein R1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

7 July 2018

Identification of the stable free radical tyrosine residue in ribonucleotide reductase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

7 July 2018

Ribonucleotide reductase small subunit p53R2 facilitates p21 induction of G1 arrest under UV irradiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

26 October 2018

Structurally dependent redox property of ribonucleotide reductase subunit p53R2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

26 October 2018

Determination of the potency and subunit-selectivity of ribonucleotide reductase inhibitors with a recombinant-holoenzyme-based in vitro assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

26 October 2018

Crystal structural studies of changes in the native dinuclear iron center of ribonucleotide reductase protein R2 from mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

26 October 2018

Preserved catalytic activity in an engineered ribonucleotide reductase R2 protein with a nonphysiological radical transfer pathway. The importance of hydrogen bond connections between the participating residues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

26 October 2018

Kinetics of transient radicals in Escherichia coli ribonucleotide reductase. Formation of a new tyrosyl radical in mutant protein R2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

26 October 2018

The conserved serine 211 is essential for reduction of the dinuclear iron center in protein R2 of Escherichia coli ribonucleotide reductase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050530

26 October 2018

Circular Dichroism and Magnetic Circular Dichroism Studies of the Active Site of p53R2 from Human and Mouse: Iron Binding and Nature of the Biferrous Site Relative to Other Ribonucleotide Reductases†

1 reference

https://pubmed.ncbi.nlm.nih.gov/20484015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Residues Important for Radical Stability in Ribonucleotide Reductase fromEscherichia coli

1 reference

https://pubmed.ncbi.nlm.nih.gov/20484015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High field EPR studies of mouse ribonucleotide reductase indicate hydrogen bonding of the tyrosyl radical

1 reference

https://pubmed.ncbi.nlm.nih.gov/20484015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The iron-oxygen reconstitution reaction in protein R2-Tyr-177 mutants of mouse ribonucleotide reductase. Epr and electron nuclear double resonance studies on a new transient tryptophan radical

1 reference

https://pubmed.ncbi.nlm.nih.gov/20484015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid development of glomerular injury and renal failure in mice lacking p53R2

1 reference

https://pubmed.ncbi.nlm.nih.gov/20484015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1535-7163.MCT-10-0023

1 reference

Europe PubMed Central

3 August 2017

release_xfdpjgboxvfodlswwclmsftcu4

1 reference

https://api.fatcat.wiki/v0/release/xfdpjgboxvfodlswwclmsftcu4

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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