(Q34639045)

3 August 2017

title

Urokinase plasminogen activator induces pro-fibrotic/m2 phenotype in murine cardiac macrophages (English)

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3 August 2017

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Jessica Meznarich

1

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3 August 2017

Laura Malchodi

2

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3 August 2017

Deri Helterline

3

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3 August 2017

Stephen A Ramsey

4

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3 August 2017

Kate Bertko

5

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3 August 2017

Tabitha Plummer

6

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3 August 2017

Abigail Plawman

7

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3 August 2017

Elizabeth Gold

8

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3 August 2017

April Stempien-Otero

9

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3 August 2017

language of work or name

English

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publication date

11 March 2013

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3 August 2017

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3 August 2017

volume

8

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3 August 2017

issue

3

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3 August 2017

page(s)

e57837

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Creative Commons Attribution 4.0 International

3 August 2017

copyright license

start time

11 March 2013

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Immune-inflammatory dysregulation modulates the incidence of progressive fibrosis and diastolic stiffness in the aging heart

7 July 2018

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The role of macrophage-derived urokinase plasminogen activator in myocardial infarct repair: urokinase attenuates ventricular remodeling

7 July 2018

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Diminished cardiac fibrosis in heart failure is associated with altered ventricular arrhythmia phenotype

7 July 2018

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Influence of myocardial fibrosis on left ventricular diastolic function: noninvasive assessment by cardiac magnetic resonance and echo

7 July 2018

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IL-6 loss causes ventricular dysfunction, fibrosis, reduced capillary density, and dramatically alters the cell populations of the developing and adult heart

7 July 2018

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Exploring the full spectrum of macrophage activation

7 July 2018

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Interleukin-1 receptor type I signaling critically regulates infarct healing and cardiac remodeling.

7 July 2018

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Cell-based therapy for myocardial ischemia and infarction: pathophysiological mechanisms.

7 July 2018

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ECM remodeling in hypertensive heart disease

7 July 2018

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The dermal microenvironment induces the expression of the alternative activation marker CD301/mMGL in mononuclear phagocytes, independent of IL-4/IL-13 signaling.

7 July 2018

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Monocyte and macrophage heterogeneity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594198

A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation).

7 July 2018

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Directing transition from innate to acquired immunity: defining a role for IL-6.

7 July 2018

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Loss or inhibition of uPA or MMP-9 attenuates LV remodeling and dysfunction after acute pressure overload in mice

7 July 2018

1 reference

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Fibrotic disease and the T(H)1/T(H)2 paradigm

7 July 2018

1 reference

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Fibrosis in left atrial tissue of patients with atrial fibrillation with and without underlying mitral valve disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594198

Alternative activation of macrophages

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594198

Myocardial extracellular matrix remodeling in transgenic mice overexpressing tumor necrosis factor alpha can be modulated by anti-tumor necrosis factor alpha therapy

7 July 2018

1 reference

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An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response

7 July 2018

1 reference

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Th1/Th2-regulated expression of arginase isoforms in murine macrophages and dendritic cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594198

Urokinase plasminogen activator: a prognostic marker in multiple types of cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594198

Nitric oxide, an autocrine regulator of wound fibroblast synthetic function.

7 July 2018

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Myocardial fibrosis: functional significance and regulatory factors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594198

Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594198

Adenovirus-mediated urokinase gene transfer induces liver regeneration and allows for efficient retrovirus transduction of hepatocytes in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594198

Targeted anticytokine therapy in patients with chronic heart failure: results of the Randomized Etanercept Worldwide Evaluation (RENEWAL).

7 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0057837

Divergent tumor necrosis factor receptor-related remodeling responses in heart failure: role of nuclear factor-kappaB and inflammatory activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0057837

Differential macrophage polarization in male and female BALB/c mice infected with coxsackievirus B3 defines susceptibility to viral myocarditis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0057837

Mechanisms of cardiac fibrosis induced by urokinase plasminogen activator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0057837

Inhibition of urokinase-type plasminogen activator or matrix metalloproteinases prevents cardiac injury and dysfunction during viral myocarditis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0057837

Macrophage-targeted overexpression of urokinase causes accelerated atherosclerosis, coronary artery occlusions, and premature death

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0057837

Influence of cytokines and growth factors in ANG II-mediated collagen upregulation by fibroblasts in rats: role of myocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0057837

Reduction of myocardial infarct size by doxycycline: a role for plasmin inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0057837

Bone marrow plasminogen activator inhibitor-1 influences the development of obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0057837

Role of interleukin-6 for LV remodeling and survival after experimental myocardial infarction

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594198

Partial reversal of established bleomycin-induced pulmonary fibrosis by rh-urokinase in a rat model.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594198

Endogenous urokinase lacks antifibrotic activity during progressive renal injury

26 October 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0057837

A self-perpetuating vicious cycle of tissue damage in human hibernating myocardium

21 January 2018

1 reference

12 December 2020

Renin expression at sites of repair in the infarcted rat heart

1 reference

12 December 2020

Urokinase-type plasminogen activator is required for the generation of a type 1 immune response to pulmonary Cryptococcus neoformans infection

1 reference

12 December 2020

Overexpression of urokinase by macrophages or deficiency of plasminogen activator inhibitor type 1 causes cardiac fibrosis in mice

1 reference

12 December 2020

In situ localization of transforming growth factor beta 1 in porcine heart: enhanced expression after chronic coronary artery constriction

1 reference

12 December 2020

Urokinase plasminogen activator activity is increased in the myocardium during coronary artery occlusion

1 reference

12 December 2020

Tumor necrosis factor-alpha and tumor necrosis factor receptors in the failing human heart

1 reference

12 December 2020

Circulating levels of cytokines and their endogenous modulators in patients with mild to severe congestive heart failure due to coronary artery disease or hypertension

1 reference

12 December 2020

Post-transcriptional regulation of extracellular matrix metalloproteinase in human heart end-stage failure secondary to ischemic cardiomyopathy

1 reference

12 December 2020

Upregulation of cell adhesion molecules and the presence of low grade inflammation in human chronic heart failure

1 reference

12 December 2020

Mechanisms underlying spontaneous and induced ventricular arrhythmias in patients with idiopathic dilated cardiomyopathy

1 reference

12 December 2020

Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure

1 reference

12 December 2020

Atrial but not ventricular fibrosis in mice expressing a mutant transforming growth factor-beta(1) transgene in the heart

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0057837

Identifiers

DOI

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3 August 2017

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3 August 2017

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