(Q34640445)

3 August 2017

title

Glutamate cysteine ligase modifier subunit deficiency and gender as determinants of acetaminophen-induced hepatotoxicity in mice (English)

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3 August 2017

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Lisa A McConnachie

1

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3 August 2017

Isaac Mohar

2

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3 August 2017

Francesca N Hudson

3

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3 August 2017

Carol B Ware

4

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3 August 2017

Warren C Ladiges

5

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3 August 2017

Carolina Fernandez

6

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3 August 2017

Sam Chatterton-Kirchmeier

7

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3 August 2017

Collin C White

8

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3 August 2017

Robert H Pierce

9

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3 August 2017

Terrance J Kavanagh

10

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3 August 2017

language of work or name

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21 June 2007

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3 August 2017

published in

Toxicological Sciences

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3 August 2017

volume

99

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3 August 2017

issue

2

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3 August 2017

page(s)

628-636

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Acetaminophen-induced liver injury is attenuated in male glutamate-cysteine ligase transgenic mice.

3 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM165

An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen

21 January 2018

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Glutamate cysteine ligase catalysis: dependence on ATP and modifier subunit for regulation of tissue glutathione levels

21 January 2018

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Acetaminophen metabolism does not contribute to gender difference in its hepatotoxicity in mouse.

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM165

Tissue specific changes in the expression of glutamate-cysteine ligase mRNAs in mice exposed to methylmercury

21 January 2018

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Acetaminophen-induced hepatotoxicity

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM165

Effect of N-acetylcysteine on acetaminophen toxicity in mice: relationship to reactive nitrogen and cytokine formation

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM165

Association of polymorphism in glutamate-cysteine ligase catalytic subunit gene with coronary vasomotor dysfunction and myocardial infarction

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM165

Acetaminophen-induced acute liver failure: results of a United States multicenter, prospective study

21 January 2018

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Apoptosis and necrosis in the liver: a tale of two deaths?

21 January 2018

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Variants in the glutamate-cysteine-ligase gene are associated with cystic fibrosis lung disease

21 January 2018

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21 January 2018

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Transcriptional regulation by the estrogen receptor of antioxidative stress enzymes and its functional implications

21 January 2018

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Polymorphism in the 5'-flanking region of human glutamate-cysteine ligase modifier subunit gene is associated with myocardial infarction

21 January 2018

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Polymorphism in glutamate-cysteine ligase modifier subunit gene is associated with impairment of nitric oxide-mediated coronary vasomotor function

21 January 2018

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Transport of glutathione, as gamma-glutamylcysteinylglycyl ester, into liver and kidney

21 January 2018

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Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple

21 January 2018

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Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

21 January 2018

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Schizophrenia and oxidative stress: glutamate cysteine ligase modifier as a susceptibility gene

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM165

Aminotransferase elevations in healthy adults receiving 4 grams of acetaminophen daily: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM165

Fluorescence-based microtiter plate assay for glutamate-cysteine ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM165

Initial characterization of the glutamate-cysteine ligase modifier subunit Gclm(-/-) knockout mouse. Novel model system for a severely compromised oxidative stress response

21 January 2018

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Metabolic insights into the hepatoprotective role of N-acetylcysteine in mouse liver

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1093/TOXSCI/KFM165

1 reference

3 August 2017

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