(Q34650076)

3 August 2017

title

Coincident resection at both ends of random, γ-induced double-strand breaks requires MRX (MRN), Sae2 (Ctp1), and Mre11-nuclease (English)

1 reference

3 August 2017

James W Westmoreland

1

1 reference

3 August 2017

Michael A Resnick

series ordinal

2

1 reference

3 August 2017

publication date

28 March 2013

1 reference

3 August 2017

1 reference

3 August 2017

volume

9

1 reference

3 August 2017

issue

3

1 reference

3 August 2017

page(s)

e1003420

1 reference

Creative Commons CC0 License

3 August 2017

copyright license

start time

28 March 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

0 references

cites work

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7 July 2018

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Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1

7 July 2018

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Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks.

7 July 2018

1 reference

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Double-strand break end resection and repair pathway choice

7 July 2018

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Functional interplay of the Mre11 nuclease and Ku in the response to replication-associated DNA damage

7 July 2018

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Alkylation base damage is converted into repairable double-strand breaks and complex intermediates in G2 cells lacking AP endonuclease.

7 July 2018

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The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection

7 July 2018

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7 July 2018

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DNA end resection--unraveling the tail

7 July 2018

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Chromosome integrity at a double-strand break requires exonuclease 1 and MRX

7 July 2018

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Mre11-Rad50-Xrs2 and Sae2 promote 5' strand resection of DNA double-strand breaks

7 July 2018

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Making the best of the loose ends: Mre11/Rad50 complexes and Sae2 promote DNA double-strand break resection

7 July 2018

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Saccharomyces cerevisiae Mre11/Rad50/Xrs2 and Ku proteins regulate association of Exo1 and Dna2 with DNA breaks

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Ku prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2

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A single-strand specific lesion drives MMS-induced hyper-mutability at a double-strand break in yeast

7 July 2018

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Mechanisms and regulation of DNA end resection

7 July 2018

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53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks

7 July 2018

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RAD50 is required for efficient initiation of resection and recombinational repair at random, gamma-induced double-strand break ends

7 July 2018

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Nucleases and helicases take center stage in homologous recombination

7 July 2018

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Hypermutability of damaged single-strand DNA formed at double-strand breaks and uncapped telomeres in yeast Saccharomyces cerevisiae.

7 July 2018

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Mre11 Dimers Coordinate DNA End Bridging and Nuclease Processing in Double-Strand-Break Repair

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610664

Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610664

Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610664

Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends

7 July 2018

1 reference

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CDK targets Sae2 to control DNA-end resection and homologous recombination

7 July 2018

1 reference

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Double-strand breaks associated with repetitive DNA can reshape the genome

7 July 2018

1 reference

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Apn1 and Apn2 endonucleases prevent accumulation of repair-associated DNA breaks in budding yeast as revealed by direct chromosomal analysis.

7 July 2018

1 reference

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Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex

7 July 2018

1 reference

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7 July 2018

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Mutations in Mre11 phosphoesterase motif I that impair Saccharomyces cerevisiae Mre11-Rad50-Xrs2 complex stability in addition to nuclease activity

7 July 2018

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RAD51-dependent break-induced replication differs in kinetics and checkpoint responses from RAD51-mediated gene conversion

7 July 2018

1 reference

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The Mre11 nuclease is not required for 5' to 3' resection at multiple HO-induced double-strand breaks

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610664

Choreography of the DNA damage response: spatiotemporal relationships among checkpoint and repair proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610664

Human Rad50/Mre11 is a flexible complex that can tether DNA ends

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610664

The single-end invasion: an asymmetric intermediate at the double-strand break to double-holliday junction transition of meiotic recombination

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610664

Fidelity of mitotic double-strand-break repair in Saccharomyces cerevisiae: a role for SAE2/COM1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610664

Three new dominant drug resistance cassettes for gene disruption in Saccharomyces cerevisiae

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610664

Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610664

The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610664

Meiotic recombination initiated by a double-strand break in rad50 delta yeast cells otherwise unable to initiate meiotic recombination.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610664

Asymmetrical recognition and activity of the I-SceI endonuclease on its site and on intron-exon junctions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610664

The repair of double-strand breaks in DNA; a model involving recombination

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610664

Induction of genome instability by DNA damage in Saccharomyces cerevisiae

7 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003420

DNA breaks promote genomic instability by impeding proper chromosome segregation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003420

The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003420

A recombination execution checkpoint regulates the choice of homologous recombination pathway during DNA double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003420

In vivo site-directed mutagenesis using oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003420

Chromosome Fragmentation after Induction of a Double-Strand Break Is an Active Process Prevented by the RMX Repair Complex

21 January 2018

2 references

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003420

21 January 2018

https://pubmed.ncbi.nlm.nih.gov/23555316

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Suppression of gross chromosomal rearrangements by the multiple functions of the Mre11-Rad50-Xrs2 complex in Saccharomyces cerevisiae

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23555316

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PGEN.1003420

1 reference

3 August 2017

1 reference

3 August 2017

1 reference