(Q34651985)

3 August 2017

title

Benzoquinone ansamycin 17AAG binds to mitochondrial voltage-dependent anion channel and inhibits cell invasion (English)

1 reference

Correction for Xie et al., Benzoquinone ansamycin 17AAG binds to mitochondrial voltage-dependent anion channel and inhibits cell invasion

3 August 2017

1 reference

corrigendum / erratum

0 references

author name string

Qian Xie

1

1 reference

3 August 2017

Robert Wondergem

2

1 reference

3 August 2017

Yuehai Shen

3

1 reference

3 August 2017

Greg Cavey

4

1 reference

3 August 2017

Jiyuan Ke

5

1 reference

3 August 2017

Ryan Thompson

6

1 reference

3 August 2017

Robert Bradley

7

1 reference

3 August 2017

Jennifer Daugherty-Holtrop

8

1 reference

3 August 2017

Yong Xu

9

1 reference

3 August 2017

Edwin Chen

10

1 reference

3 August 2017

Hanan Omar

11

1 reference

3 August 2017

Neal Rosen

12

1 reference

3 August 2017

David Wenkert

13

1 reference

3 August 2017

H Eric Xu

14

1 reference

3 August 2017

George F Vande Woude

15

1 reference

3 August 2017

language of work or name

English

0 references

publication date

22 February 2011

1 reference

Proceedings of the National Academy of Sciences of the United States of America

3 August 2017

number of pages

6

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

3 August 2017

volume

108

1 reference

3 August 2017

issue

10

1 reference

3 August 2017

page(s)

4105-4110

1 reference

Calcium flickers steer cell migration.

3 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

Solution Structure of the Integral Human Membrane Protein VDAC-1 in Detergent Micelles

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

VDAC regulation: role of cytosolic proteins and mitochondrial lipids

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

Enzymatic reduction and glutathione conjugation of benzoquinone ansamycin heat shock protein 90 inhibitors: relevance for toxicity and mechanism of action

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

NVP-AUY922: a novel heat shock protein 90 inhibitor active against xenograft tumor growth, angiogenesis, and metastasis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

Voltage-gated ion channels, new targets in anti-cancer research.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

Combination of trastuzumab and tanespimycin (17-AAG, KOS-953) is safe and active in trastuzumab-refractory HER-2 overexpressing breast cancer: a phase I dose-escalation study

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

Regulation of tumor cell mitochondrial homeostasis by an organelle-specific Hsp90 chaperone network.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

Correct folding of the beta-barrel of the human membrane protein VDAC requires a lipid bilayer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

Design, synthesis, and biological evaluation of hydroquinone derivatives of 17-amino-17-demethoxygeldanamycin as potent, water-soluble inhibitors of Hsp90.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

Formation of 17-allylamino-demethoxygeldanamycin (17-AAG) hydroquinone by NAD(P)H:quinone oxidoreductase 1: role of 17-AAG hydroquinone in heat shock protein 90 inhibition

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

The actin cytoskeleton: a key regulator of apoptosis and ageing?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

Geldanamycin derivative inhibition of HGF/SF-mediated Met tyrosine kinase receptor-dependent urokinase-plasminogen activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

Geldanamycins exquisitely inhibit HGF/SF-mediated tumor cell invasion

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

Effects of 17-allylamino-17-demethoxygeldanamycin (17-AAG) on pediatric acute lymphoblastic leukemia (ALL) with respect to Bcr-Abl status and imatinib mesylate sensitivity.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

Engineered biosynthesis of geldanamycin analogs for Hsp90 inhibition.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

Quinone reductases multitasking in the metabolic world

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

Synthesis and biological activities of novel 17-aminogeldanamycin derivatives

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

Synthesis and biological evaluation of a new class of geldanamycin derivatives as potent inhibitors of Hsp90.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

TRPV channels and modulation by hepatocyte growth factor/scatter factor in human hepatoblastoma (HepG2) cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

Heat shock protein 90 as a molecular target for cancer therapeutics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

Voltage-dependent anion channels control the release of the superoxide anion from mitochondria to cytosol.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

Energized mitochondria increase the dynamic range over which inositol 1,4,5-trisphosphate activates store-operated calcium influx.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

Respiring mitochondria determine the pattern of activation and inactivation of the store-operated Ca(2+) current I(CRAC).

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

The geldanamycins are potent inhibitors of the hepatocyte growth factor/scatter factor-met-urokinase plasminogen activator-plasmin proteolytic network

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

DT-Diaphorase expression and tumor cell sensitivity to 17-allylamino, 17-demethoxygeldanamycin, an inhibitor of heat shock protein 90

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

Structural basis for inhibition of the Hsp90 molecular chaperone by the antitumor antibiotics radicicol and geldanamycin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

Mitochondria and apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053964

Geldanamycin leads to superoxide formation by enzymatic and non-enzymatic redox cycling. Implications for studies of Hsp90 and endothelial cell nitric-oxide synthase

7 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1015181108

Filter binding assay for the geldanamycin–heat shock protein 90 interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1015181108

A fluorescence polarization assay for inhibitors of Hsp90.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1015181108

HGF/SF and menthol increase human glioblastoma cell calcium and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1015181108

Targeting heat shock protein 90 with non-quinone inhibitors: a novel chemotherapeutic approach in human hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1015181108

Preclinical toxicity of a geldanamycin analog, 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin (17-DMAG), in rats and dogs: potential clinical relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1015181108

Ca2+ -reversible inhibition of the mitochondrial megachannel by ubiquinone analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1015181108

Hsp90 charged-linker truncation reverses the functional consequences of weakened hydrophobic contacts in the N domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1015181108

A Ubiquinone-binding Site Regulates the Mitochondrial Permeability Transition Pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1015181108

The mitochondrial channel VDAC has a cation-selective open state

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21368131

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Voltage gating of VDAC is regulated by nonlamellar lipids of mitochondrial membranes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21368131

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1015181108

1 reference

3 August 2017

0 references

1 reference

3 August 2017

1 reference