(Q34655896)

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The 5-HT2C receptor agonist Ro60-0175 reduces cocaine self-administration and reinstatement induced by the stressor yohimbine, and contextual cues

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

The 5-HT2C receptor agonist Ro60-0175 reduces cocaine self-administration and reinstatement induced by the stressor yohimbine, and contextual cues (English)

1 reference

Europe PubMed Central

3 August 2017

1 reference

ChEBI release 2020-05-28

author name string

Paul J Fletcher

1

1 reference

Europe PubMed Central

3 August 2017

Zoë Rizos

2

1 reference

Europe PubMed Central

3 August 2017

Judy Sinyard

3

1 reference

Europe PubMed Central

3 August 2017

Maria Tampakeras

4

1 reference

Europe PubMed Central

3 August 2017

Guy A Higgins

5

1 reference

Europe PubMed Central

3 August 2017

language of work or name

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publication date

25 July 2007

1 reference

Europe PubMed Central

3 August 2017

Neuropsychopharmacology

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Europe PubMed Central

3 August 2017

33

1 reference

Europe PubMed Central

3 August 2017

6

1 reference

Europe PubMed Central

3 August 2017

1402-1412

1 reference

Europe PubMed Central

3 August 2017

https://scigraph.springernature.com/pub.10.1038/sj.npp.1301509

0 references

Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite

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21 January 2018

Localization of the 5-hydroxytryptamine2C receptor protein in human and rat brain using specific antisera.

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Neurobiology of relapse to heroin and cocaine seeking: an update and clinical implications

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A role of ventral tegmental area glutamate in contextual cue-induced relapse to heroin seeking.

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Serotonin 5-HT2A and 5-HT2C receptors as potential targets for modulation of psychostimulant use and dependence

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21 January 2018

Differential roles of 5-HT receptor subtypes in cue and cocaine reinstatement of cocaine-seeking behavior in rats

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21 January 2018

Dopamine D1 and D2 mediation of the discriminative stimulus properties of d-amphetamine and cocaine.

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A role for the prefrontal cortex in stress- and cocaine-induced reinstatement of cocaine seeking in rats

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21 January 2018

Neurobiological mechanisms of panic anxiety: biochemical and behavioral correlates of yohimbine-induced panic attacks

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21 January 2018

Immunohistochemical localisation of the 5-HT2C receptor protein in the rat CNS.

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Effect of dopamine receptor antagonists on renewal of cocaine seeking by reexposure to drug-associated contextual cues

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Central serotonin2C receptor: from physiology to pathology

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SB 242084, a selective serotonin2C receptor antagonist, increases dopaminergic transmission in the mesolimbic system

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21 January 2018

Biochemical and electrophysiological evidence that RO 60-0175 inhibits mesolimbic dopaminergic function through serotonin(2C) receptors

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21 January 2018

Pattern of expression of the serotonin2C receptor messenger RNA in the basal ganglia of adult rats

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21 January 2018

A role for the CRF-containing pathway from central nucleus of the amygdala to bed nucleus of the stria terminalis in the stress-induced reinstatement of cocaine seeking in rats

1 reference

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Contribution of serotonin (5-hydroxytryptamine; 5-HT) 5-HT2 receptor subtypes to the hyperlocomotor effects of cocaine: acute and chronic pharmacological analyses

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Hyperlocomotive and discriminative stimulus effects of cocaine are under the control of serotonin(2C) (5-HT(2C)) receptors in rat prefrontal cortex

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21 January 2018

Injection of the 5-HT2C receptor agonist Ro60-0175 into the ventral tegmental area reduces cocaine-induced locomotor activity and cocaine self-administration

1 reference

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21 January 2018

Effect of chronic m-CPP on locomotion, hypophagia, plasma corticosterone and 5-HT2C receptor levels in the rat

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21 January 2018

The role of the dorsomedial prefrontal cortex, basolateral amygdala, and dorsal hippocampus in contextual reinstatement of cocaine seeking in rats

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21 January 2018

Leptin regulation of the mesoaccumbens dopamine pathway.

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21 January 2018

Effects of environmental and pharmacological stressors on c-fos and corticotropin-releasing factor mRNA in rat brain: Relationship to the reinstatement of alcohol seeking

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21 January 2018

Activation of 5-HT(2C) receptors reduces the locomotor and rewarding effects of nicotine

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Agonist diversity in 5-HT(2C) receptor-mediated weight control in rats

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Activation of central melanocortin pathways by fenfluramine

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Serotonin 2C receptor agonists and the behavioural satiety sequence in mice.

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21 January 2018

Serotonin and drug reward: focus on 5-HT2C receptors

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21 January 2018

Leptin receptor signaling in midbrain dopamine neurons regulates feeding

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Disruption of PTEN coupling with 5-HT2C receptors suppresses behavioral responses induced by drugs of abuse

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21 January 2018

Selective 6OHDA-induced destruction of mesolimbic dopamine neurons: abolition of psychostimulant-induced locomotor activity in rats

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21 January 2018

SB 242084, a selective and brain penetrant 5-HT2C receptor antagonist

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21 January 2018

Role of alpha-2 adrenoceptors in stress-induced reinstatement of alcohol seeking and alcohol self-administration in rats

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21 January 2018

Pharmacological blockade of alpha2-adrenoceptors induces reinstatement of cocaine-seeking behavior in squirrel monkeys

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21 January 2018

Limbic and motor circuitry underlying footshock-induced reinstatement of cocaine-seeking behavior.

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21 January 2018

Management of cocaine abuse and dependence

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Serotonin 5-ht2c receptor agonists: potential for the treatment of obesity

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5-Hydroxytryptamine 2C (5-HT2C) receptor agonists as potential antiobesity agents

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A range of research-based pharmacotherapies for addiction

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Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats

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Distribution of the serotonin 5-HT2 receptor family mRNAs: comparison between 5-HT2A and 5-HT2C receptors.

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Functional characterization of agonists at recombinant human 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cells

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Stimulation of 5-hydroxytryptamine (5-HT(2C) ) receptors in the ventrotegmental area inhibits stress-induced but not basal dopamine release in the rat prefrontal cortex

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Progressive ratio schedules in drug self-administration studies in rats: a method to evaluate reinforcing efficacy

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Tolerance to the anorectic effect of dexfenfluramine in rats: role of serotonin, cholecystokinin, and neuropeptide Y.

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The reinstatement model of drug relapse: history, methodology and major findings

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The anxiogenic drug yohimbine reinstates methamphetamine seeking in a rat model of drug relapse

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Induction of c-Fos expression in specific areas of the fear circuitry in rat forebrain by anxiogenic drugs

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Yohimbine-induced withdrawal and anxiety symptoms in opioid-dependent patients

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Rapid desensitization of the serotonin(2C) receptor system: effector pathway and agonist dependence

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Therapeutic potential of targeting the endocannabinoids: implications for the treatment of obesity, metabolic syndrome, drug abuse and smoking cessation

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Functional Selectivity and Classical Concepts of Quantitative Pharmacology

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Comparative effects of continuous infusion of mCPP, Ro 60-0175 and d-fenfluramine on food intake, water intake, body weight and locomotor activity in rats.

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How can drug addiction help us understand obesity?

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Further studies to examine the nature of dexfenfluramine-induced suppression of heroin self-administration.

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Chronic treatment with fluvoxamine desensitizes 5-HT2C receptor-mediated hypolocomotion in rats

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Activation of group II metabotropic glutamate receptors in the nucleus accumbens shell attenuates context-induced relapse to heroin seeking

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7 January 2021

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Noradrenergic mechanisms in stress and anxiety: I. Preclinical studies

1 reference

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inferred from DOI database lookup

Noradrenergic mechanisms in stress and anxiety: II. Clinical studies

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Acute administration of amitriptyline and mianserin increases dopamine release in the rat nucleus accumbens: possible involvement of serotonin 2C receptors

1 reference

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Serotonin(2C) receptors tonically suppress the activity of mesocortical dopaminergic and adrenergic, but not serotonergic, pathways: a combined dialysis and electrophysiological analysis in the rat

1 reference

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The circuitry mediating cocaine-induced reinstatement of drug-seeking behavior.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.NPP.1301509

1 reference

Europe PubMed Central

3 August 2017

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1 reference

Europe PubMed Central

3 August 2017

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