(Q34655913)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18344983%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

title

NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18344983%20AND%20SRC:MED&resulttype=core&format=json

Heat shock protein 83 Dmel_CG1242

4 January 2020

main subject

molecular chaperones

0 references

1 reference

GOA release 2020-03-11

1 reference

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18344983%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

author name string

R Grace Zhai

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18344983%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Fan Zhang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18344983%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

P Robin Hiesinger

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18344983%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Yu Cao

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18344983%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Claire M Haueter

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18344983%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

language of work or name

English

0 references

publication date

16 March 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18344983%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18344983%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

volume

452

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18344983%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

issue

7189

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18344983%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

page(s)

887-891

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18344983%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nature06721

4 January 2020

exact match

0 references

cites work

Identification of a critical site in Wld(s): essential for Nmnat enzyme activity and axon-protective function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150538

Drosophila NMNAT maintains neural integrity independent of its NAD synthesis activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150538

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150538

NAD(+) and axon degeneration revisited: Nmnat1 cannot substitute for Wld(S) to delay Wallerian degeneration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150538

The AXH domain of Ataxin-1 mediates neurodegeneration through its interaction with Gfi-1/Senseless proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150538

A local mechanism mediates NAD-dependent protection of axon degeneration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150538

Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150538

Structural characterization of a human cytosolic NMN/NaMN adenylyltransferase and implication in human NAD biosynthesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150538

Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150538

Structure of the universal stress protein of Haemophilus influenzae

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150538

Compartmental neurodegeneration and synaptic plasticity in the Wld(s) mutant mouse

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150538

A Ufd2/D4Cole1e chimeric protein and overexpression of Rbp7 in the slow Wallerian degeneration (WldS) mouse

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150538

Dynamic visualization of nervous system in live Drosophila

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150538

Two distinct mechanisms operate in the reactivation of heat-denatured proteins by the mitochondrial Hsp70/Mdj1p/Yge1p chaperone system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150538

Hsp90 as a capacitor for morphological evolution

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150538

Mycobacterium tuberculosis 16-kDa antigen (Hsp16.3) functions as an oligomeric structure in vitro to suppress thermal aggregation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150538

Protein disaggregation mediated by heat-shock protein Hsp104.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150538

Wlds-mediated protection of dopaminergic fibers in an animal model of Parkinson disease

7 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE06721

Wlds protection distinguishes axon degeneration following injury from naturally occurring developmental pruning

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150538

The Drosophila cell corpse engulfment receptor Draper mediates glial clearance of severed axons

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150538

Neuroprotection after transient global cerebral ischemia in Wld(s) mutant mice.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150538

The Wlds mutation delays robust loss of motor and sensory axons in a genetic model for myelin-related axonopathy.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150538

Crystal structure of the E. coli Hsp100 ClpB N-terminal domain

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150538

Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150538

Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150538

Inhibiting axon degeneration and synapse loss attenuates apoptosis and disease progression in a mouse model of motoneuron disease

26 October 2018

1 reference

12 December 2020

Delayed wallerian degeneration in the central nervous system of Ola mice: an ultrastructural study

1 reference

12 December 2020

Persistence of neuromuscular junctions after axotomy in mice with slow Wallerian degeneration (C57BL/WldS)

1 reference

12 December 2020

New structure--novel fold?

1 reference

12 December 2020

Hsp70 and Hsp40 chaperone activities in the cytoplasm and the nucleus of mammalian cells

1 reference

12 December 2020

Identifiers

DOI

10.1038/NATURE06721

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18344983%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

4 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18344983%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

PubMed publication ID

18344983

1 reference