(Q34662867)

3 August 2017

1 reference

title

Genetics of chronic lymphocytic leukemia: genomic aberrations and V(H) gene mutation status in pathogenesis and clinical course (English)

1 reference

chronic lymphocytic leukemia

3 August 2017

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S Stilgenbauer

1

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3 August 2017

L Bullinger

2

1 reference

3 August 2017

P Lichter

3

1 reference

3 August 2017

H Döhner

4

1 reference

3 August 2017

German CLL Study Group (GCLLSG). Chronic lymphocytic leukemia

5

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3 August 2017

1 June 2002

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3 August 2017

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3 August 2017

16

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3 August 2017

993-1007

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3 August 2017

6

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https://scigraph.springernature.com/pub.10.1038/sj.leu.2402537

3 August 2017

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cites work

Clustering of aberrations to specific chromosomes in human neoplasms. III. Incidence and geographic distribution of chromosome aberrations in 856 cases

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Prognostic subgroups in B-cell chronic lymphocytic leukemia defined by specific chromosomal abnormalities

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Cytogenetic Findings and Survival in B-cell Chronic Lymphocytic Leukemia. Second IWCCLL Compilation of Data on 662 Patients

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Genomic aberrations and survival in chronic lymphocytic leukemia

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Cellular origin of human B-cell lymphomas.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

The pathogenesis of chronic lymphocytic leukemia: analysis of the antibody repertoire

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Chromosome abnormalities of leukaemic B lymphocytes in chronic lymphocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Extra chromosome 12 in chronic lymphocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Cytogenetic and molecular abnormalities in chronic lymphocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Cytogenetic and immunologic characterization of mitotic cells in chronic lymphocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Detection of complete and partial chromosome gains and losses by comparative genomic in situ hybridization.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Detection of amplified DNA sequences by reverse chromosome painting using genomic tumor DNA as probe

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Is non-isotopic in situ hybridization finally coming of age?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Detection of chromosome aberrations in the human interphase nucleus by visualization of specific target DNAs with radioactive and non-radioactive in situ hybridization techniques: diagnosis of trisomy 18 with probe L1.84.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Chromosome aberrations in B-cell chronic lymphocytic leukemia: reassessment based on molecular cytogenetic analysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Chromosomes and causation of human cancer and leukemia. XLV. Chromosome patterns in stimulated lymphocytes of chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Prognostic importance of cytogenetic abnormalities in patients with chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Prognostic significance of chromosome abnormalities in chronic lymphocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

The most common chromosome change in 86 chronic B cell or T cell tumors: a 14q32 translocation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Clonal chromosome abnormalities in chronic lymphocytic leukemia patients revealed by TPA stimulation of whole blood cultures

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Correlation of chromosome abnormalities with laboratory features and clinical course in B-cell chronic lymphocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Chromosome abnormalities involving band 13q14 in hematologic malignancies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Chromosome 13--a new marker for B-cell chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Frequent clonal abnormalities of chromosome band 13q14 in B-cell chronic lymphocytic leukemia: multiple clones, subclones, and nonclonal alterations in 82 midwestern patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Chromosome abnormalities in chronic lymphocytic leukemia revealed by TPA as a mitogen

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

A new characteristic karyotypic anomaly in lymphoproliferative disorders

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

A 14;19 translocation in B-cell chronic lymphocytic leukemia: a new recurring chromosome aberration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Karyotypic evolution in B-cell chronic lymphocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Secondary abnormalities of chromosome 6q in B-cell chronic lymphocytic leukemia: a sequential study of karyotypic instability in 51 patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Chronic lymphocytic leukemia cells with allelic deletions at 13q14 commonly have one intact RB1 gene: evidence for a role of an adjacent locus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Evidence for a new tumour suppressor locus (DBM) in human B-cell neoplasia telomeric to the retinoblastoma gene.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Retinoblastoma gene deletions in B-cell chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Molecular cytogenetic analysis of RB-1 deletions in chronic B-cell leukemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Cloning and gene mapping of the chromosome 13q14 region deleted in chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Cloning of two candidate tumor suppressor genes within a 10 kb region on chromosome 13q14, frequently deleted in chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Construction of a 780-kb PAC, BAC, and cosmid contig encompassing the minimal critical deletion involved in B cell chronic lymphocytic leukemia at 13q14.3.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Expressed sequences as candidates for a novel tumor suppressor gene at band 13q14 in B-cell chronic lymphocytic leukemia and mantle cell lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Exclusion of Leu1 and Leu2 genes as tumor suppressor genes in 13q14.3-deleted B-CLL

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

BCMSUN, a candidate gene for B-cell chronic lymphocytic leukemia and mantle-cell lymphoma, has an independently expressed homolog on 1p22-p31, BCMSUN-like.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

B-cell neoplasia associated gene with multiple splicing (BCMS): the candidate B-CLL gene on 13q14 comprises more than 560 kb covering all critical regions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Trisomy 12 defines a group of CLL with atypical morphology: correlation between cytogenetic, clinical and laboratory features in 544 patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

In B-cell chronic lymphocytic leukaemia chromosome 17 abnormalities and not trisomy 12 are the single most important cytogenetic abnormalities for the prognosis: a cytogenetic and immunophenotypic study of 480 unselected newly diagnosed patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Deletions at 11q identify a subset of patients with typical CLL who show consistent disease progression and reduced survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Analysis of deletions of the long arm of chromosome 11 in hematologic malignancies with fluorescence in situ hybridization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Molecular cytogenetic delineation of a novel critical genomic region in chromosome bands 11q22.3-923.1 in lymphoproliferative disorders

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

A radiation hybrid map of 506 STS markers spanning human chromosome 11.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

ATM: from gene to function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Atm-deficient mice: a paradigm of ataxia telangiectasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Biallelic mutations in the ATM gene in T-prolymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Clustering of missense mutations in the ataxia-telangiectasia gene in a sporadic T-cell leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Inactivation of ataxia telangiectasia mutated gene in B-cell chronic lymphocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Ataxia telangiectasia mutated-deficient B-cell chronic lymphocytic leukemia occurs in pregerminal center cells and results in defective damage response and unrepaired chromosome damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

p53 dysfunction in B-cell chronic lymphocytic leukemia: inactivation of ATM as an alternative to TP53 mutation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Molecular characterization of deletion at 11q22.1-23.3 in mantle cell lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Mantle cell lymphoma is characterized by inactivation of the ATM gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Chromosome aberrations in B-cell chronic lymphocytic leukemia. Pathogenetic and clinical implications

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Cytogenetic mapping of the duplicated segment of chromosome 12 in lymphoproliferative disorders

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Trisomy 12 is uncommon in typical chronic lymphocytic leukaemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Amplification of multiple regions of chromosome 12, including 12q13-15, in chronic lymphocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

FISH identifies different types of duplications with 12q13-15 as the commonly involved segment in B-cell lymphoproliferative malignancies characterized by partial trisomy 12.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Extra chromosome 12 and prognosis in chronic lymphocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

The sequential analysis of trisomy 12 in B-cell chronic lymphocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Cytogenetic deletion maps of hematologic neoplasms: circumstantial evidence for tumor suppressor loci

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Incidence and clinical significance of 6q deletions in B cell chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

A 3-cM commonly deleted region in 6q21 in leukemias and lymphomas delineated by fluorescence in situ hybridization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

PRAD1, a candidate BCL1 oncogene: mapping and expression in centrocytic lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Characterization of a candidate bcl-1 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Molecular cloning of the chromosomal breakpoint of B-cell lymphomas and leukemias with the t(11;14) chromosome translocation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Clustering of breakpoints on chromosome 11 in human B-cell neoplasms with the t(11 ; 14) chromosome translocation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Variant translocation of the bcl-2 gene to immunoglobulin lambda light chain gene in chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Preferential linkage of bcl-2 to immunoglobulin light chain gene in chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Lack of 5' BCL2 rearrangements in B-cell leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

BCL3 rearrangement and t(14;19)(q32;q13) in lymphoproliferative disorders

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Cloning of the chromosome translocation breakpoint junction of the t(14;19) in chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Identification of a transcriptional unit adjacent to the breakpoint in the 14;19 translocation of chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

The proto-oncogene bcl-3 encodes an I kappa B protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

CDKN2 gene deletion is not found in chronic lymphoid leukaemias of B- and T-cell origin but is frequent in acute lymphoblastic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

B cells of chronic lymphatic leukemia express V genes in unmutated form

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Insight into the origin and clonal history of B-cell tumors as revealed by analysis of immunoglobulin variable region genes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Frequent somatic hypermutation of the 5' noncoding region of the BCL6 gene in B-cell lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

The POZ domain: a conserved protein-protein interaction motif

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Chromosomal translocations cause deregulated BCL6 expression by promoter substitution in B cell lymphoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Identification of three subgroups of B cell chronic lymphocytic leukemia based upon mutations of BCL-6 and IgV genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Analysis of somatic mutation in five B cell subsets of human tonsil

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

CD38 expression is a poor predictor for VH gene mutational status and prognosis in chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

CD38 expression as an important prognostic factor in B-cell chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Clinical significance of CD38 expression in chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

CDNA microarray gene expression analysis of B-cell chronic lymphocytic leukemia proposes potential new prognostic markers involved in lymphocyte trafficking

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402537

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2402537

1 reference

Dimensions Publication ID

3 August 2017

0 references

1 reference