(Q34672078)

English

Low dose of the liver X receptor agonist, AZ876, reduces atherosclerosis in APOE*3Leiden mice without affecting liver or plasma triglyceride levels.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21175581%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Low dose of the liver X receptor agonist, AZ876, reduces atherosclerosis in APOE*3Leiden mice without affecting liver or plasma triglyceride levels (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21175581%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

liver X receptor agonist

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atherosclerosis

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based on heuristic

inferred from title

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based on heuristic

inferred from title

9

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18 January 2020

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Jwa van der Hoorn

1

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18 January 2020

D Lindén

2

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18 January 2020

U Lindahl

3

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18 January 2020

Mea Bekkers

4

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18 January 2020

M Voskuilen

5

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18 January 2020

R Nilsson

6

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18 January 2020

J Oscarsson

7

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18 January 2020

El Lindstedt

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18 January 2020

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1 April 2011

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18 January 2020

British Journal of Pharmacology

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18 January 2020

162

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18 January 2020

7

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18 January 2020

1553-1563

1 reference

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18 January 2020

LXR ligand lowers LDL cholesterol in primates, is lipid neutral in hamster, and reduces atherosclerosis in mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

7 July 2018

Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

7 July 2018

Regulation of cholesterologenesis by the oxysterol receptor, LXRalpha.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

7 July 2018

Regulation of macrophage functions by PPAR-alpha, PPAR-gamma, and LXRs in mice and men.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

7 July 2018

Cholesterol efflux pathways and other potential mechanisms involved in the athero-protective effect of high density lipoproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

7 July 2018

Liver X receptor and farnesoid X receptor as therapeutic targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

7 July 2018

Mouse models for atherosclerosis and pharmaceutical modifiers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

7 July 2018

Effect of T0901317 on hepatic proinflammatory gene expression in apoE-/- mice fed a high-fat/high-cholesterol diet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

7 July 2018

Cholesteryl ester transfer protein decreases high-density lipoprotein and severely aggravates atherosclerosis in APOE*3-Leiden mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

7 July 2018

Intestinal ABCA1 directly contributes to HDL biogenesis in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

7 July 2018

Liver X receptors as integrators of metabolic and inflammatory signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

7 July 2018

Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

7 July 2018

Persistence of high density lipoprotein particles in obese mice lacking apolipoprotein A-I

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

7 July 2018

A simple method for the isolation and purification of total lipides from animal tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

7 July 2018

Inflammation in atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

7 July 2018

Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

7 July 2018

Synthetic LXR ligand inhibits the development of atherosclerosis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

7 July 2018

Identification of a nonsteroidal liver X receptor agonist through parallel array synthesis of tertiary amines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

7 July 2018

Orphan nuclear receptors as eLiXiRs and FiXeRs of sterol metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

7 July 2018

Acyl-CoA:cholesterol acyltransferase inhibitor avasimibe reduces atherosclerosis in addition to its cholesterol-lowering effect in ApoE*3-Leiden mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

7 July 2018

Role of LXRs in control of lipogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

7 July 2018

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

7 July 2018

The role of orphan nuclear receptors in the regulation of cholesterol homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

7 July 2018

An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

7 July 2018

Diet-induced hyperlipoproteinemia and atherosclerosis in apolipoprotein E3-Leiden transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

7 July 2018

Correlation between serum levels of some cholesterol precursors and activity of HMG-CoA reductase in human liver.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

7 July 2018

Dietary cholesterol increases transcription of the human cholesteryl ester transfer protein gene in transgenic mice. Dependence on natural flanking sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

7 July 2018

Differential effects of amlodipine and atorvastatin treatment and their combination on atherosclerosis in ApoE*3-Leiden transgenic mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01168.X

21 January 2018

Synthetic LXR agonists increase LDL in CETP species

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01168.X

21 January 2018

Olmesartan and pravastatin additively reduce development of atherosclerosis in APOE*3Leiden transgenic mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01168.X

21 January 2018

Rosuvastatin reduces atherosclerosis development beyond and independent of its plasma cholesterol-lowering effect in APOE*3-Leiden transgenic mice: evidence for antiinflammatory effects of rosuvastatin

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01168.X

21 January 2018

Raising HDL cholesterol without inducing hepatic steatosis and hypertriglyceridemia by a selective LXR modulator

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01168.X

21 January 2018

Pharmacological activation of liver X receptors promotes reverse cholesterol transport in vivo

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01168.X

21 January 2018

Niemann-Pick C1-like 1 is required for an LXR agonist to raise plasma HDL cholesterol in mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01168.X

21 January 2018

T-0901317, a synthetic liver X receptor ligand, inhibits development of atherosclerosis in LDL receptor-deficient mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01168.X

21 January 2018

LXR agonist suppresses atherosclerotic lesion growth and promotes lesion regression in apoE*3Leiden mice: time course and mechanisms

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01168.X

21 January 2018

Guide to Receptors and Channels (GRAC), 4th Edition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

26 October 2018

Effect of low dose atorvastatin versus diet-induced cholesterol lowering on atherosclerotic lesion progression and inflammation in apolipoprotein E*3-Leiden transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057293

26 October 2018

Fenofibrate reduces atherogenesis in ApoE*3Leiden mice: evidence for multiple antiatherogenic effects besides lowering plasma cholesterol

1 reference

https://pubmed.ncbi.nlm.nih.gov/21175581

12 December 2020

based on heuristic

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10.1111/J.1476-5381.2010.01168.X

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21175581%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21175581%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21175581%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

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