(Q34673321)

3 August 2017

1 reference

title

Pharmacogenetics and folate metabolism -- a promising direction (English)

1 reference

3 August 2017

1 reference

Cornelia M Ulrich

1

1 reference

PubMed ID

12052139

3 August 2017

Kim Robien

series ordinal

2

1 reference

PubMed ID

12052139

3 August 2017

Rachel Sparks

series ordinal

3

1 reference

3 August 2017

1 May 2002

1 reference

3 August 2017

1 reference

3 August 2017

3

1 reference

3 August 2017

3

1 reference

3 August 2017

299-313

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The history of folic acid

3 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

THE CONCENTRATION OF “FOLIC ACID”

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

SYNTHESIS OF A COMPOUND IDENTICAL WITH THE L. CASEI FACTOR ISOLATED FROM LIVER.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

The alpha folate receptor is highly activated in malignant pleural mesothelioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Folate receptor type beta is a neutrophilic lineage marker and is differentially expressed in myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Substrate flux through methylenetetrahydrofolate dehydrogenase: predicted effects of the concentration of methylenetetrahydrofolate on its partitioning into pathways leading to nucleotide biosynthesis or methionine regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Biological and clinical implications of the MTHFR C677T polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Uracil misincorporation in human DNA detected using single cell gel electrophoresis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Folate, vitamin B12, homocysteine status and DNA damage in young Australian adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

DNA damage in folate deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Micronuclei in lymphocytes and exfoliated buccal cells of postmenopausal women with dietary changes in folate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Threshold Methotrexate Concentration for In Vivo Inhibition of DNA Synthesis in Normal and Tumorous Target Tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

The comparative efficacy and toxicity of second-line drugs in rheumatoid arthritis results of two metaanalyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Methotrexate in rheumatoid arthritis. Toxic effects as the major factor in limiting long-term treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Mutations in dihydropteroate synthase gene of Pneumocystis carinii in HIV patients with Pneumocystis carinii pneumonia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Rapid detection of dihydropteroate polymorphism in AIDS-related Pneumocystis carinii pneumonia by restriction fragment length polymorphism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Update on antifolate drugs targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Transport of folate compounds by leukemic cells. Evidence for a single influx carrier for methotrexate, 5-methyltetrahydrofolate, and folate in CCRF-CEM human lymphoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Inhibition of 5-aminoimidazole-4-carboxamide ribotide transformylase, adenosine deaminase and 5'-adenylate deaminase by polyglutamates of methotrexate and oxidized folates and by 5-aminoimidazole-4-carboxamide riboside and ribotide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Effect of methotrexate on intracellular folate pools in purified myeloid precursor cells from normal human bone marrow

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Pemetrexed: a multitargeted antifolate agent with promising activity in solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Capecitabine: a review of its use in the treatment of advanced or metastatic colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and risk of molecularly defined subtypes of childhood acute leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Neonatal and fetal methylenetetrahydrofolate reductase genetic polymorphisms: an examination of C677T and A1298C mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Genetic polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) in ethnic populations in Texas; a report of a novel MTHFR polymorphic site, G1793A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Role in translation of a triple tandemly repeated sequence in the 5'-untranslated region of human thymidylate synthase mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Influence of a methionine synthase (D919G) polymorphism on plasma homocysteine and folate levels and relation to risk of myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

A prospective study of methylenetetrahydrofolate reductase and methionine synthase gene polymorphisms, and risk of colorectal adenoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuria

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Functional methionine synthase deficiency (cblE and cblG): clinical and biochemical heterogeneity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

A common variant in methionine synthase reductase combined with low cobalamin (vitamin B12) increases risk for spina bifida

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

The methionine synthase reductase (MTRR) A66G polymorphism is a novel genetic determinant of plasma homocysteine concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

The human cystathionine beta-synthase (CBS) gene: complete sequence, alternative splicing, and polymorphisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Is mutated serine hydroxymethyltransferase (SHMT) involved in the etiology of neural tube defects?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Genetic polymorphism (G80A) of reduced folate carrier gene in ethnic populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

MTHFR (C677T) polymorphisms and stage III colon cancer: response to therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Pharmacogenetics of methotrexate: toxicity among marrow transplantation patients varies with the methylenetetrahydrofolate reductase C677T polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Methotrexate and cyclosporine compared with cyclosporine alone for prophylaxis of acute graft versus host disease after marrow transplantation for leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Ethnic variation in the thymidylate synthase enhancer region polymorphism among Caucasian and Asian populations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Polymorphisms of the repeated sequences in the enhancer region of the thymidylate synthase gene promoter may predict downstaging after preoperative chemoradiation in rectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

A polymorphism in the enhancer region of the thymidylate synthase promoter influences the survival of colorectal cancer patients treated with 5-fluorouracil

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

A common mutation in the methylenetetrahydrofolate reductase gene is associated with an accumulation of formylated tetrahydrofolates in red blood cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

The role of folic acid and Vitamin B12 in genomic stability of human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Allelotype of colorectal carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Oral mucositis and the clinical and economic outcomes of hematopoietic stem-cell transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Pharmacogenetics and cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Molecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Oral uracil-tegafur: an alternative to intravenous 5-fluorouracil?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Worldwide distribution of a common methylenetetrahydrofolate reductase mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

Association between polymorphisms of folate- and methionine-metabolizing enzymes and susceptibility to malignant lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.3.299

21 January 2018

Identifiers

DOI

10.1517/14622416.3.3.299

1 reference

3 August 2017

1 reference

PubMed ID

12052139