(Q34675944)

3 August 2017

title

The molecular basis of distinct aggregation pathways of islet amyloid polypeptide (English)

1 reference

3 August 2017

Lei Wei

1

1 reference

3 August 2017

Ping Jiang

2

1 reference

3 August 2017

Weixin Xu

3

1 reference

3 August 2017

Hai Li

4

1 reference

3 August 2017

Hua Zhang

5

1 reference

3 August 2017

Liangyu Yan

6

1 reference

3 August 2017

Mary B Chan-Park

7

1 reference

3 August 2017

Xue-Wei Liu

8

1 reference

3 August 2017

Kai Tang

9

1 reference

3 August 2017

Yuguang Mu

10

1 reference

3 August 2017

Konstantin Pervushin

11

1 reference

3 August 2017

language of work or name

English

0 references

publication date

10 December 2010

1 reference

Journal of Biological Chemistry

3 August 2017

published in

1 reference

3 August 2017

volume

286

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3 August 2017

issue

8

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3 August 2017

page(s)

6291-6300

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EGCG remodels mature alpha-synuclein and amyloid-beta fibrils and reduces cellular toxicity.

3 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Helix stabilization precedes aqueous and bilayer-catalyzed fiber formation in islet amyloid polypeptide

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Multiple tight phospholipid-binding modes of alpha-synuclein revealed by solution NMR spectroscopy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

The role of the 14-20 domain of the islet amyloid polypeptide in amyloid formation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Atomic structure of the cross-β spine of islet amyloid polypeptide (amylin)

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Islet amyloid in type 2 diabetes, and the toxic oligomer hypothesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Dimeric structures of alpha-synuclein bind preferentially to lipid membranes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Sedimentation studies on human amylin fail to detect low-molecular-weight oligomers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Peptide conformation and supramolecular organization in amylin fibrils: constraints from solid-state NMR.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Familial Alzheimer's disease mutations alter the stability of the amyloid beta-protein monomer folding nucleus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Atomic structures of amyloid cross-beta spines reveal varied steric zippers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Toxic human islet amyloid polypeptide (h-IAPP) oligomers are intracellular, and vaccination to induce anti-toxic oligomer antibodies does not prevent h-IAPP-induced beta-cell apoptosis in h-IAPP transgenic mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Are amyloid diseases caused by protein aggregates that mimic bacterial pore-forming toxins?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Accurate determination of pyridine-poly(amidoamine) dendrimer absolute binding constants with the OPLS-AA force field and direct integration of radial distribution functions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Protein aggregation and its consequences for human disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

GROMACS: fast, flexible, and free

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

The Amber biomolecular simulation programs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Mechanism of prion propagation: amyloid growth occurs by monomer addition

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Amyloidogenicity and cytotoxicity of recombinant mature human islet amyloid polypeptide (rhIAPP).

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Exploring protein native states and large-scale conformational changes with a modified generalized born model

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Pancreatic beta-cell granule peptides form heteromolecular complexes which inhibit islet amyloid polypeptide fibril formation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Liquid-solid transition in nuclei of protein crystals

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Structure determination of micelle-like intermediates in amyloid beta -protein fibril assembly by using small angle neutron scattering

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Amyloid beta-protein oligomerization: prenucleation interactions revealed by photo-induced cross-linking of unmodified proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Nucleated conformational conversion and the replication of conformational information by a prion determinant

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Analysis of amylin cleavage products provides new insights into the amyloidogenic region of human amylin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

From the globular to the fibrous state: protein structure and structural conversion in amyloid formation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

A novel assay in vitro of human islet amyloid polypeptide amyloidogenesis and effects of insulin secretory vesicle peptides on amyloid formation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

A computer perspective of membranes: molecular dynamics studies of lipid bilayer systems

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Common core structure of amyloid fibrils by synchrotron X-ray diffraction.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Kinetic theory of fibrillogenesis of amyloid beta-protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

On the nucleation and growth of amyloid beta-protein fibrils: detection of nuclei and quantitation of rate constants

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

The pancreatic islet cells in insular amyloidosis in human diabetic and non-diabetic adults.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

Human islet amyloid polypeptide transgenic mice as a model of non-insulin-dependent diabetes mellitus (NIDDM).

7 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.166678

Human amylin oligomer growth and fibril elongation define two distinct phases in amyloid formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.166678

Is there a cause-and-effect relationship between alpha-synuclein fibrillization and Parkinson's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.166678

Residual structure in islet amyloid polypeptide mediates its interactions with soluble insulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.166678

Identification of the ribosome binding sites of translation initiation factor IF3 by multidimensional heteronuclear NMR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.166678

Screening for pharmacologic inhibitors of amyloid fibril formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.166678

The fidelity of replication of the three-base-pair set adenine/thymine, hypoxanthine/cytosine and 6-thiopurine/5-methyl-2-pyrimidinone with T7 DNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.166678

Direct observation of oligomeric species formed in the early stages of amyloid fibril formation using electrospray ionisation mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.166678

Association of highly compact type II diabetes related islet amyloid polypeptide intermediate species at physiological temperature revealed by diffusion NMR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.166678

Inhibition of human IAPP fibril formation does not prevent beta-cell death: evidence for distinct actions of oligomers and fibrils of human IAPP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.166678

Identification of a novel human islet amyloid polypeptide beta-sheet domain and factors influencing fibrillogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.166678

Assembly dynamics of two-beta sheets revealed by molecular dynamics simulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.166678

Elucidating the mechanism of lipid membrane-induced IAPP fibrillogenesis and its inhibition by the red wine compound resveratrol: a synchrotron X-ray reflectivity study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.166678

Titration_DB: storage and analysis of NMR-monitored protein pH titration curves

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057848

The protofilament substructure of amyloid fibrils11Edited by F. E. Cohen

26 October 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.166678

Titration_DB: Storage and analysis of NMR-monitored protein pH titration curves

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.166678

Effect of pH and insulin on fibrillogenesis of islet amyloid polypeptide in vitro

21 January 2018

1 reference

12 December 2020

[18] Quantification of β-sheet amyloid fibril structures with thioflavin T

1 reference

12 December 2020

Conformational transitions of islet amyloid polypeptide (IAPP) in amyloid formation in vitro

1 reference

12 December 2020

Molecular mapping of the recognition interface between the islet amyloid polypeptide and insulin

1 reference

12 December 2020

Transient hydrogen bonds identified on the surface of the NMR solution structure of Hirudin

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.166678

1 reference

3 August 2017

1 reference

3 August 2017

1 reference