(Q34676371)

3 August 2017

Dexmedetomidine-induced sedation does not mimic the neurobehavioral phenotypes of sleep in Sprague Dawley rat (English)

1 reference

3 August 2017

0 references

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25325438%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Ralph Lydic

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25325438%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

author name string

Abigail G Garrity

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25325438%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Simhadri Botta

2

1 reference

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6 June 2020

Stephanie B Lazar

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25325438%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Erin Swor

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25325438%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Giancarlo Vanini

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25325438%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

language of work or name

1 reference

1 January 2015

1 reference

3 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25325438%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

volume

38

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25325438%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25325438%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

page(s)

73-84

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25325438%20AND%20SRC:MED&resulttype=core&format=json

Eszopiclone and dexmedetomidine depress ventilation in obese rats with features of metabolic syndrome

6 June 2020

cites work

1 reference

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Practice guidelines for the perioperative management of patients with obstructive sleep apnea: an updated report by the American Society of Anesthesiologists Task Force on Perioperative Management of patients with obstructive sleep apnea

7 July 2018

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Temporal disorganization of circadian rhythmicity and sleep-wake regulation in mechanically ventilated patients receiving continuous intravenous sedation

7 July 2018

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Control of sleep and wakefulness

7 July 2018

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Waking and dreaming consciousness: neurobiological and functional considerations

7 July 2018

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Neuronal adenosine release, and not astrocytic ATP release, mediates feedback inhibition of excitatory activity

7 July 2018

1 reference

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Rapid eye movement sleep debt accrues in mice exposed to volatile anesthetics

7 July 2018

1 reference

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Buprenorphine disrupts sleep and decreases adenosine concentrations in sleep-regulating brain regions of Sprague Dawley rat.

7 July 2018

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Review articles: postoperative delirium: acute change with long-term implications

7 July 2018

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Endogenous GABA levels in the pontine reticular formation are greater during wakefulness than during rapid eye movement sleep

7 July 2018

1 reference

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Differential effects of isoflurane on high-frequency and low-frequency γ oscillations in the cerebral cortex and hippocampus in freely moving rats

7 July 2018

1 reference

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General anesthesia, sleep, and coma

7 July 2018

1 reference

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Adenosine, energy metabolism and sleep homeostasis

7 July 2018

1 reference

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Dexmedetomidine: new insights

7 July 2018

1 reference

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GABA(A) receptors in the pontine reticular formation of C57BL/6J mouse modulate neurochemical, electrographic, and behavioral phenotypes of wakefulness

7 July 2018

1 reference

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Benzodiazepine receptor agonists cause drug-specific and state-specific alterations in EEG power and acetylcholine release in rat pontine reticular formation

7 July 2018

1 reference

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Isoflurane anesthesia does not satisfy the homeostatic need for rapid eye movement sleep

7 July 2018

1 reference

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Incidence and predictors of hypertension during high-dose dexmedetomidine sedation for pediatric MRI.

7 July 2018

1 reference

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Opioid-induced decreases in rat brain adenosine levels are reversed by inhibiting adenosine deaminase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262959

Discharge profiles of identified GABAergic in comparison to cholinergic and putative glutamatergic basal forebrain neurons across the sleep-wake cycle

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262959

Identification of cholinergic and non-cholinergic neurons in the pons expressing phosphorylated cyclic adenosine monophosphate response element-binding protein as a function of rapid eye movement sleep.

7 July 2018

1 reference

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How (and why) the immune system makes us sleep.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262959

Astrocytic modulation of sleep homeostasis and cognitive consequences of sleep loss

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262959

Adenosine A(1) and A(2A) receptors in mouse prefrontal cortex modulate acetylcholine release and behavioral arousal

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262959

Gabapentin acts within the locus coeruleus to alleviate neuropathic pain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262959

Gamma-aminobutyric acid-mediated neurotransmission in the pontine reticular formation modulates hypnosis, immobility, and breathing during isoflurane anesthesia.

7 July 2018

1 reference

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Consciousness and anesthesia

7 July 2018

1 reference

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The role of cholinergic basal forebrain neurons in adenosine-mediated homeostatic control of sleep: lessons from 192 IgG-saporin lesions

7 July 2018

1 reference

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Measurement of immediate-early gene activation- c-fos and beyond

7 July 2018

1 reference

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An emerging link between general anesthesia and sleep

7 July 2018

1 reference

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An essential role for orexins in emergence from general anesthesia

7 July 2018

1 reference

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Automatic analysis of single-channel sleep EEG: validation in healthy individuals.

7 July 2018

1 reference

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Electroencephalogram spindle activity during dexmedetomidine sedation and physiological sleep

7 July 2018

1 reference

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How many polysomnograms must sleep fellows score before becoming proficient at scoring sleep?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262959

The median preoptic nucleus reciprocally modulates activity of arousal-related and sleep-related neurons in the perifornical lateral hypothalamus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262959

Sleep and GABA levels in the oral part of rat pontine reticular formation are decreased by local and systemic administration of morphine.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262959

Adenosine and sleep-wake regulation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262959

Recovery from sleep deprivation occurs during propofol anesthesia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262959

Adenosinergic inhibition of basal forebrain wakefulness-active neurons: a simultaneous unit recording and microdialysis study in freely behaving cats

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262959

The alpha2-adrenoceptor agonist dexmedetomidine converges on an endogenous sleep-promoting pathway to exert its sedative effects

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262959

Practice guidelines for sedation and analgesia by non-anesthesiologists

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262959

Sleep deprivation-induced c-fos and junB expression in the rat brain: effects of duration and timing.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262959

Brain site-specificity of extracellular adenosine concentration changes during sleep deprivation and spontaneous sleep: an in vivo microdialysis study

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262959

Discharge patterns of neurons in cholinergic regions of the basal forebrain during waking and sleep

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262959

The effects of increasing plasma concentrations of dexmedetomidine in humans

7 July 2018

1 reference

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On the functional significance of c-fos induction during the sleep-waking cycle

7 July 2018

1 reference

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Rat strain differences suggest a role for corticotropin-releasing hormone in modulating sleep.

7 July 2018

1 reference

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Pharmacokinetic-pharmacodynamic characterization of the cardiovascular, hypnotic, EEG and ventilatory responses to dexmedetomidine in the rat.

7 July 2018

1 reference

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Regional cerebral blood flow throughout the sleep-wake cycle. An H2(15)O PET study.

7 July 2018

1 reference

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Antisense technology reveals the alpha2A adrenoceptor to be the subtype mediating the hypnotic response to the highly selective agonist, dexmedetomidine, in the locus coeruleus of the rat.

7 July 2018

1 reference

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Regulation of CREB phosphorylation in the suprachiasmatic nucleus by light and a circadian clock

7 July 2018

1 reference

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Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle.

7 July 2018

1 reference

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7 July 2018

1 reference

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Behavioural characteristics of sleep in rats under different light/dark conditions.

7 July 2018

1 reference

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Noradrenergic locus coeruleus neurons: their distant connections and their relationship to neighboring (including cholinergic and GABAergic) neurons of the central gray and reticular formation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262959

Comparison of the behavioral and neurochemical effects of the two optical enantiomers of medetomidine, a selective alpha-2-adrenoceptor agonist

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262959

A hypnotic response to dexmedetomidine, an alpha 2 agonist, is mediated in the locus coeruleus in rats

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262959

7 July 2018

1 reference

https://api.crossref.org/works/10.5665%2FSLEEP.4328

Effect of sleep deprivation on righting reflex in the rat is partially reversed by administration of adenosine A1 and A2 receptor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.5665%2FSLEEP.4328

State-specific effects of sevoflurane anesthesia on sleep homeostasis: selective recovery of slow wave but not rapid eye movement sleep

21 January 2018

1 reference

https://api.crossref.org/works/10.5665%2FSLEEP.4328

Dexmedetomidine exerts dose-dependent age-independent antinociception but age-dependent hypnosis in Fischer rats

21 January 2018

1 reference

https://api.crossref.org/works/10.5665%2FSLEEP.4328

Norepinephrine-containing neurons: changes in spontaneous discharge patterns during sleeping and waking

21 January 2018

1 reference

https://api.crossref.org/works/10.5665%2FSLEEP.4328

An exaggerated hypertensive response to glycopyrrolate therapy for bradycardia associated with high-dose dexmedetomidine

21 January 2018

1 reference

https://api.crossref.org/works/10.5665%2FSLEEP.4328

Perioperative infusion of dexmedetomidine at a high dose reduces postoperative analgesic requirements: a randomized control trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.5665%2FSLEEP.4328

Morphine inhibits acetylcholine release in rat prefrontal cortex when delivered systemically or by microdialysis to basal forebrain

21 January 2018

1 reference

https://api.crossref.org/works/10.5665%2FSLEEP.4328

Ionotropic and metabotropic receptors, protein kinase A, protein kinase C, and Src contribute to C-fiber-induced ERK activation and cAMP response element-binding protein phosphorylation in dorsal horn neurons, leading to central sensitization.

21 January 2018

1 reference

https://api.crossref.org/works/10.5665%2FSLEEP.4328

Sleep neurobiology: relevance for mechanistic studies of anaesthesia.

21 January 2018

1 reference

https://api.crossref.org/works/10.5665%2FSLEEP.4328

Sleep medicine and anesthesia: a new horizon for anesthesiologists.

21 January 2018

1 reference

https://api.crossref.org/works/10.5665%2FSLEEP.4328

Sleep deprivation potentiates the onset and duration of loss of righting reflex induced by propofol and isoflurane

21 January 2018

1 reference

https://api.crossref.org/works/10.5665%2FSLEEP.4328

Adenosine and sleep homeostasis in the Basal forebrain.

21 January 2018

1 reference

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Daily immediate early gene expression in the suprachiasmatic nucleus of male and female Octodon degus.

21 January 2018

1 reference

https://api.crossref.org/works/10.5665%2FSLEEP.4328

Sleep loss and REM sleep loss are hyperalgesic.

21 January 2018

1 reference

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Ketamine and MK-801 decrease acetylcholine release in the pontine reticular formation, slow breathing, and disrupt sleep.

26 October 2018

1 reference

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Neuroprotection by the alpha 2-adrenoreceptor agonist dexmedetomidine in a focal model of cerebral ischemia.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262959

c-fos mRNA in the suprachiasmatic nuclei in vitro shows a circadian rhythm and responds to a serotonergic agonist

26 October 2018

1 reference

12 December 2020

Alpha-2 adrenergic modulation of sleep: time-of-day-dependent pharmacodynamic profiles of dexmedetomidine and clonidine in the rat

1 reference

12 December 2020

Action of dexmedetomidine on rat locus coeruleus neurones: intracellular recording in vitro

1 reference

12 December 2020

Assessing the depth of dexmedetomidine-induced sedation with electroencephalogram (EEG)-based spectral entropy

1 reference

12 December 2020

Identifiers

DOI

10.5665/SLEEP.4328

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25325438%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25325438%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25325438%20AND%20SRC:MED&resulttype=core&format=json