(Q34678100)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21133889%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Retrochalcone derivatives are positive allosteric modulators at synaptic and extrasynaptic GABA(A) receptors in vitro (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21133889%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21133889%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Alexandre Specht

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21133889%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author name string

Akiko Miyamoto

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21133889%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Adeline Martz

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21133889%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Hitoshi Ishibashi

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21133889%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Marie Kueny-Stotz

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21133889%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Stefan Chassaing

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21133889%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Raymond Brouillard

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21133889%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Lia Prado de Carvalho

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21133889%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Maurice Goeldner

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21133889%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Junichi Nabekura

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21133889%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Mogens Nielsen

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21133889%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Thomas Grutter

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21133889%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

language of work or name

English

0 references

publication date

1 March 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21133889%20AND%20SRC:MED&resulttype=core&format=json

British Journal of Pharmacology

17 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21133889%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

162

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21133889%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

issue

6

1 reference

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17 January 2020

page(s)

1326-1339

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21133889%20AND%20SRC:MED&resulttype=core&format=json

Structurally diverse amphiphiles exhibit biphasic modulation of GABAA receptors: similarities and differences with neurosteroid actions.

17 January 2020

cites work

1 reference

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Extrasynaptic GABAA receptors: form, pharmacology, and function

7 July 2018

1 reference

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The complexity of the GABAA receptor shapes unique pharmacological profiles.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058165

GABA A receptors: subtypes provide diversity of function and pharmacology

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058165

Ethanol modulates synaptic and extrasynaptic GABAA receptors in the thalamus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058165

Small molecules with structural similarities to siderophores as novel antimicrobials against Mycobacterium tuberculosis and Yersinia pestis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058165

Stoichiometric analysis of the TM2 6' phenylalanine mutation on desensitization in alpha1beta2 and alpha1beta2gamma2 GABA A receptors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058165

Activation of GABAA receptors: views from outside the synaptic cleft.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058165

Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058165

Tandem subunits effectively constrain GABAA receptor stoichiometry and recapitulate receptor kinetics but are insensitive to GABAA receptor-associated protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058165

Determinants of amentoflavone interaction at the GABA(A) receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058165

Neurosteroids: endogenous regulators of the GABA(A) receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058165

Tonically active GABA A receptors: modulating gain and maintaining the tone.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058165

Techniques: applications of the nerve-bouton preparation in neuropharmacology

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058165

The relative amount of cRNA coding for gamma2 subunits affects stimulation by benzodiazepines in GABA(A) receptors expressed in Xenopus oocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058165

Differential cross talk of ROD compounds with the benzodiazepine binding site

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058165

Advances in flavonoid research since 1992.

7 July 2018

1 reference

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GABA(A) receptors: immunocytochemical distribution of 13 subunits in the adult rat brain.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058165

Bicuculline and gabazine are allosteric inhibitors of channel opening of the GABAA receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058165

Potentiation by sevoflurane of the gamma-aminobutyric acid-induced chloride current in acutely dissociated CA1 pyramidal neurones from rat hippocampus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058165

GABAA receptor function in developing rat thalamic reticular neurons: whole cell recordings of GABA-mediated currents and modulation by clonazepam

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058165

Barbiturate interactions at the human GABAA receptor: dependence on receptor subunit combination

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058165

GABAA receptor pharmacology

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058165

The modulatory action of loreclezole at the gamma-aminobutyric acid type A receptor is determined by a single amino acid in the beta 2 and beta 3 subunit

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058165

A single histidine in GABAA receptors is essential for benzodiazepine agonist binding

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058165

Five subtypes of type A gamma-aminobutyric acid receptors identified in neurons by double and triple immunofluorescence staining with subunit-specific antibodies

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058165

Subunit arrangement of gamma-aminobutyric acid type A receptors

7 July 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01142.X

Forced subunit assembly in alpha1beta2gamma2 GABAA receptors. Insight into the absolute arrangement

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01142.X

Extrasynaptic GABAA receptors of thalamocortical neurons: a molecular target for hypnotics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01142.X

GABAA receptor-mediated tonic inhibition in thalamic neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01142.X

Flavan-3-ol derivatives are positive modulators of GABA(A) receptors with higher efficacy for the alpha(2) subtype and anxiolytic action in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01142.X

Flavonoid modulation of ionic currents mediated by GABA(A) and GABA(C) receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01142.X

Pharmacological studies on synthetic flavonoids: comparison with diazepam

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01142.X

Flumazenil-independent positive modulation of gamma-aminobutyric acid action by 6-methylflavone at human recombinant alpha1beta2gamma2L and alpha1beta2 GABAA receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01142.X

6-Methylflavanone, a more efficacious positive allosteric modulator of gamma-aminobutyric acid (GABA) action at human recombinant alpha2beta2gamma2L than at alpha1beta2gamma2L and alpha1beta2 GABA(A) receptors expressed in Xenopus oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01142.X

Evaluation of anti-inflammatory and analgesic activity of a novel rigid 3, 4-dihydroxy chalcone in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01142.X

Endocannabinoids contribute to metabotropic glutamate receptor-mediated inhibition of GABA release onto hippocampal CA3 pyramidal neurons in an isolated neuron/bouton preparation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01142.X

An extrasynaptic GABAA receptor mediates tonic inhibition in thalamic VB neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01142.X

Flavylium salts as in vitro precursors of potent ligands to brain GABA-A receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01142.X

Developmental maturation of synaptic and extrasynaptic GABAA receptors in mouse thalamic ventrobasal neurones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01142.X

Calcium channels in the GABAergic presynaptic nerve terminals projecting to meynert neurons of the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01142.X

Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01142.X

Pharmacological characterization of agonists at delta-containing GABAA receptors: Functional selectivity for extrasynaptic receptors is dependent on the absence of gamma2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01142.X

Benzodiazepines induce a conformational change in the region of the gamma-aminobutyric acid type A receptor alpha(1)-subunit M3 membrane-spanning segment.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058165

High affinity of the naturally-occurring biflavonoid, amentoflavon, to brain benzodiazepine receptors in vitro

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21133889

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The gamma 2 subunit of the GABAA receptor is concentrated in synaptic junctions containing the alpha 1 and beta 2/3 subunits in hippocampus, cerebellum and globus pallidus

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21133889

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/J.1476-5381.2010.01142.X

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21133889%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21133889%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

21133889

1 reference