(Q34678844)

3 August 2017

title

Identification of novel small-molecule inducers of fetal hemoglobin using pharmacophore and 'PSEUDO' receptor models (English)

1 reference

3 August 2017

Regine Bohacek

1

1 reference

3 August 2017

Michael S Boosalis

2

1 reference

3 August 2017

Colin McMartin

3

1 reference

3 August 2017

Douglas V Faller

4

1 reference

3 August 2017

Susan P Perrine

5

1 reference

3 August 2017

publication date

1 May 2006

1 reference

Chemical Biology and Drug Design

3 August 2017

published in

1 reference

3 August 2017

volume

67

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3 August 2017

issue

5

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3 August 2017

page(s)

318-328

1 reference

Induction of fetal globin in beta-thalassemia: Cellular obstacles and molecular progress

3 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263278

Fetal globin induction--can it cure beta thalassemia?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263278

Induction of human gamma globin gene expression by histone deacetylase inhibitors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263278

Induction of fetal hemoglobin by propionic and butyric acid derivatives: correlations between chemical structure and potency of Hb F induction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263278

Short-chain fatty acid derivatives induce fetal globin expression and erythropoiesis in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263278

Pharmacologic modulation of fetal hemoglobin.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263278

Short-chain fatty acid derivatives stimulate cell proliferation and induce STAT-5 activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263278

Sustained induction of fetal hemoglobin by pulse butyrate therapy in sickle cell disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263278

QXP: powerful, rapid computer algorithms for structure-based drug design.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263278

Delay in the fetal globin switch in infants of diabetic mothers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263278

Butyrate infusions in the ovine fetus delay the biologic clock for globin gene switching

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263278

Structural details on the binding of antihypertensive drugs captopril and enalaprilat to human testicular angiotensin I-converting enzyme.

7 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2006.00386.X

Hydroxamide derivatives of short-chain fatty acids are potent inducers of human fetal globin gene expression

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263278

Structure-activity relationships on phenylalanine-containing inhibitors of histone deacetylase: in vitro enzyme inhibition, induction of differentiation, and inhibition of proliferation in Friend leukemic cells.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263278

Oral isobutyramide therapy in patients with thalassemia intermedia: results of a phase II open study.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263278

Ortho-substituted benzofused macrocyclic lactams as zinc metalloprotease inhibitors

26 October 2018

1 reference

12 December 2020

Oral sodium phenylbutyrate therapy in homozygous beta thalassemia: a clinical trial

1 reference

12 December 2020

Meta-substituted benzofused macrocyclic lactams as zinc metalloprotease inhibitors

1 reference

12 December 2020

On the induction of fetal hemoglobin by butyrates: in vivo and in vitro studies with sodium butyrate and comparison of combination treatments with 5-AzaC and AraC

1 reference

12 December 2020

Sodium butyrate enhances fetal globin gene expression in erythroid progenitors of patients with Hb SS and beta thalassemia

1 reference

12 December 2020

Flexible matching of test ligands to a 3D pharmacophore using a molecular superposition force field: comparison of predicted and experimental conformations of inhibitors of three enzymes

1 reference

12 December 2020

Stimulation of fetal hemoglobin production by short chain fatty acids

1 reference

12 December 2020

Metabolic persistence of fetal hemoglobin

1 reference

12 December 2020

A short-term trial of butyrate to stimulate fetal-globin-gene expression in the beta-globin disorders

1 reference

12 December 2020

10.1111/J.1747-0285.2006.00386.X

Identifiers

DOI

1 reference

3 August 2017

1 reference

3 August 2017

1 reference