(Q34687289)

3 August 2017

title

Substitution of active site tyrosines with tryptophan alters the free energy for nucleotide flipping by human alkyladenine DNA glycosylase (English)

1 reference

3 August 2017

Jenna M Hendershot

1

1 reference

3 August 2017

Abigail E Wolfe

series ordinal

2

1 reference

3 August 2017

Patrick J O'Brien

series ordinal

3

1 reference

3 August 2017

language of work or name

English

0 references

publication date

3 February 2011

1 reference

3 August 2017

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3 August 2017

volume

50

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3 August 2017

issue

11

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3 August 2017

page(s)

1864-1874

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describes a project that uses

3 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3059348/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Frameshift mutagenesis and microsatellite instability induced by human alkyladenine DNA glycosylase.

7 July 2018

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Efficient recognition of an unpaired lesion by a DNA repair glycosylase

7 July 2018

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Kinetic mechanism for the flipping and excision of 1,N(6)-ethenoadenine by human alkyladenine DNA glycosylase

7 July 2018

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Human AP endonuclease 1 stimulates multiple-turnover base excision by alkyladenine DNA glycosylase

7 July 2018

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Aag-initiated base excision repair drives alkylation-induced retinal degeneration in mice

7 July 2018

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Pre-tRNA turnover catalyzed by the yeast nuclear RNase P holoenzyme is limited by product release

7 July 2018

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Human alkyladenine DNA glycosylase employs a processive search for DNA damage

7 July 2018

1 reference

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Substrate binding pocket residues of human alkyladenine-DNA glycosylase critical for methylating agent survival

7 July 2018

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Human methyl purine DNA glycosylase and DNA polymerase beta expression collectively predict sensitivity to temozolomide

7 July 2018

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Enzymatic capture of an extrahelical thymine in the search for uracil in DNA

7 July 2018

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Pre-steady-state kinetic study of substrate specificity of Escherichia coli formamidopyrimidine--DNA glycosylase

7 July 2018

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Organ and cell specificity of base excision repair mutants in mice

7 July 2018

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Structure of a DNA glycosylase searching for lesions

7 July 2018

1 reference

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Kinetics of substrate recognition and cleavage by human 8-oxoguanine-DNA glycosylase

7 July 2018

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N-methylpurine DNA glycosylase overexpression increases alkylation sensitivity by rapidly removing non-toxic 7-methylguanine adducts

7 July 2018

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Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA.

7 July 2018

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Oxanine DNA glycosylase activity from Mammalian alkyladenine glycosylase

7 July 2018

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Protein tolerance to random amino acid change

7 July 2018

1 reference

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Dissecting the broad substrate specificity of human 3-methyladenine-DNA glycosylase

7 July 2018

1 reference

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The adaptive imbalance in base excision-repair enzymes generates microsatellite instability in chronic inflammation.

7 July 2018

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Human Alkyladenine DNA Glycosylase Uses Acid−Base Catalysis for Selective Excision of Damaged Purines

7 July 2018

1 reference

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Effects of hydrogen bonding within a damaged base pair on the activity of wild type and DNA-intercalating mutants of human alkyladenine DNA glycosylase

7 July 2018

1 reference

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Presteady-state analysis of a single catalytic turnover by Escherichia coli uracil-DNA glycosylase reveals a "pinch-pull-push" mechanism

7 July 2018

1 reference

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Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059348

Kinetic mechanism of damage site recognition and uracil flipping by Escherichia coli uracil DNA glycosylase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059348

Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision

7 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059348

7 July 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059348

Generation of a strong mutator phenotype in yeast by imbalanced base excision repair

26 October 2018

1 reference

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Specific binding of a designed pyrrolidine abasic site analog to multiple DNA glycosylases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059348

Base excision repair deficient mice lacking the Aag alkyladenine DNA glycosylase.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059348

Purification and characterization of human 3-methyladenine-DNA glycosylase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059348

Fluorescent modification of adenosine-containing coenzymes. Biological activities and spectroscopic properties.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059348

Suggestions for "safe" residue substitutions in site-directed mutagenesis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059348

Stacking and T-shape competition in aromatic-aromatic amino acid interactions

7 July 2018

1 reference

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26 October 2018

Identifiers

DOI

10.1021/BI101856A

1 reference

3 August 2017

1 reference

3 August 2017

1 reference