(Q34688072)

3 August 2017

1 reference

title

Endogenous oxidative stress: relationship to aging, longevity and caloric restriction (English)

1 reference

3 August 2017

1 reference

Gustavo Barja

1

1 reference

3 August 2017

1 June 2002

1 reference

3 August 2017

Ageing Research Reviews

1 reference

3 August 2017

1

1 reference

3 August 2017

3

1 reference

3 August 2017

397-411

1 reference

Association of a protein structure of probable membrane derivation with HeLa cell mitochondrial DNA near its origin of replication

3 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Mitochondrial oxygen radical generation and leak: sites of production in states 4 and 3, organ specificity, and relation to aging and longevity

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Localization at complex I and mechanism of the higher free radical production of brain nonsynaptic mitochondria in the short-lived rat than in the longevous pigeon.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Low mitochondrial free radical production per unit O2 consumption can explain the simultaneous presence of high longevity and high aerobic metabolic rate in birds.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Relationship between antioxidants, lipid peroxidation and aging

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Oxidative Decay of DNA

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

The free radical theory of aging matures

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Age- and peroxidative stress-related modifications of the cerebral enzymatic activities linked to mitochondria and the glutathione system.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Protein oxidation in aging, disease, and oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Role of mitochondrial DNA mutations in human aging: implications for the central nervous system and muscle

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Mice lacking extracellular superoxide dismutase are more sensitive to hyperoxia

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity, and loss in temporal and spatial memory by chronic administration of the spin-trapping compound N-tert-butyl-alpha-phenylnitrone.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Changes in the levels of enzymes which modulate the antioxidant balance occur during aging and correlate with cellular damage

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Measurements of protein carbonyls, ortho- and meta-tyrosine and oxidative phosphorylation complex activity in mitochondria from young and old rats

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

The reductive hotspot hypothesis: an update

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Mice with a homozygous null mutation for the most abundant glutathione peroxidase, Gpx1, show increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Regional distribution of iron, transferrin, ferritin, and oxidatively-modified proteins in young and aged Fischer 344 rat brains.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Induction of beta-polymerase mRNA by DNA-damaging agents in Chinese hamster ovary cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Caloric restriction decreases mitochondrial free radical generation at complex I and lowers oxidative damage to mitochondrial DNA in the rat heart

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Effect of short-term caloric restriction on H2O2 production and oxidative DNA damage in rat liver mitochondria and location of the free radical source

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

The biologic clock: the mitochondria?

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

ADP-regulation of mitochondrial free radical production is different with complex I- or complex II-linked substrates: implications for the exercise paradox and brain hypermetabolism.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Sites and mechanisms responsible for the low rate of free radical production of heart mitochondria in the long-lived pigeon

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

H2O2 production of heart mitochondria and aging rate are slower in canaries and parakeets than in mice: sites of free radical generation and mechanisms involved

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

8-oxo-deoxyguanosine levels in heart and brain mitochondrial and nuclear DNA of two mammals and three birds in relation to their different rates of aging

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Localization of the site of oxygen radical generation inside the complex I of heart and nonsynaptic brain mammalian mitochondria.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

8-hydroxyguanine levels in nuclear DNA and its repair activity in rat organs associated with age.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Mice deficient in cellular glutathione peroxidase develop normally and show no increased sensitivity to hyperoxia

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Effect of voluntary exercise on longevity of rats

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mut

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Non-linear accumulation of 8-hydroxy-2'-deoxyguanosine, a marker of oxidized DNA damage, during aging

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

8OHdG levels in brain do not indicate oxidative DNA damage in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Tissue-specific distribution of multiple mitochondrial DNA rearrangements during human aging

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Comparison of mitochondrial pro-oxidant generation and anti-oxidant defenses between rat and pigeon: possible basis of variation in longevity and metabolic potential

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Exercise intensity and longevity in men. The Harvard Alumni Health Study

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Caloric restriction attenuates dityrosine cross-linking of cardiac and skeletal muscle proteins in aging mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Mitochondrial DNA 4977 bp deletion and OH8dG levels correlate in the brain of aged subjects but not Alzheimer's disease patients.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Simultaneous induction of SOD, glutathione reductase, GSH, and ascorbate in liver and kidney correlates with survival during aging

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Effect of thyroid hormones on mitochondrial oxygen free radical production and DNA oxidative damage in the rat heart

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Age-dependent increases in oxidative damage to DNA, lipids, and proteins in human skeletal muscle

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Multi-organ characterization of mitochondrial genomic rearrangements in ad libitum and caloric restricted mice show striking somatic mitochondrial DNA rearrangements with age

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Mouse models of mitochondrial disease, oxidative stress, and senescence.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Mitochondrial disease in superoxide dismutase 2 mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Proteolysis, caloric restriction and aging.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Presence of a DNA-4236 bp deletion and 8-hydroxy-deoxyguanosine in mouse cardiac mitochondrial DNA during aging

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Targeted deletion of the cytosolic Cu/Zn-superoxide dismutase gene (Sod1) increases susceptibility to noise-induced hearing loss

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Mitochondrial DNA mutations associated with aging and degenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Mitochondrial genome mutation in cell death and aging

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Aging increases Nepsilon-(carboxymethyl)lysine and caloric restriction decreases Nepsilon-(carboxyethyl)lysine and Nepsilon-(malondialdehyde)lysine in rat heart mitochondrial proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Xeroderma pigmentosum group E binding factor recognizes a broad spectrum of DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

The rate of free radical production as a determinant of the rate of aging: evidence from the comparative approach

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

The mammalian Mre11-Rad50-nbs1 protein complex: integration of functions in the cellular DNA-damage response

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Normal oxidative damage to mitochondrial and nuclear DNA is extensive

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Mitochondria, aging and longevity--a new perspective.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Mitochondria, oxidative stress and aging.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Mitochondrial oxidative stress plays a key role in aging and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Relationship between antioxidant defenses and longevity in different mammalian species

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Hydrogen peroxide production by liver mitochondria in different species.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Effect of age and caloric restriction on DNA oxidative damage in different tissues of C57BL/6 mice

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Oxidative stress and aging in the Mongolian gerbil (Meriones unguiculatus)

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Protein oxidation and aging

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Protein oxidation and proteolysis during aging and oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

NADH- and NADPH-dependent formation of superoxide anions by bovine heart submitochondrial particles and NADH–ubiquinone reductase preparation

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Superoxide dismutase: correlation with life-span and specific metabolic rate in primate species

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Susceptibility of heterozygous MnSOD gene-knockout mice to oxygen toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

The rate of mitochondrial mutagenesis is faster in mice than humans

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

Microarray profiling of gene expression in aging and its alteration by caloric restriction in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2802%2900008-9

7 January 2021

10.1016/S1568-1637(02)00008-9

Identifiers

DOI

1 reference

3 August 2017

1 reference

PubMed ID

12067594