(Q34689304)

English

Phase I and pharmacokinetic study of etaracizumab (Abegrin), a humanized monoclonal antibody against alphavbeta3 integrin receptor, in patients with advanced solid tumors.

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17876527%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Phase I and pharmacokinetic study of etaracizumab (Abegrin), a humanized monoclonal antibody against alphavbeta3 integrin receptor, in patients with advanced solid tumors (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17876527%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

0 references

1 reference

based on heuristic

inferred from title

monoclonal antibody

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

Sandrine Faivre

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17876527%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

author name string

Catherine Delbaldo

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17876527%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Eric Raymond

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17876527%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Karina Vera

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17876527%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Luz Hammershaimb

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17876527%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Karen Kaucic

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17876527%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Stéphanie Lozahic

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17876527%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Michel Marty

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17876527%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

publication date

18 September 2007

1 reference

Europe PubMed Central

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7 January 2020

Investigational New Drugs

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17876527%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

26

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17876527%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

35-43

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17876527%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17876527%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

https://scigraph.springernature.com/pub.10.1007/s10637-007-9077-0

0 references

Requirement of vascular integrin alpha v beta 3 for angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrin alpha(v)beta3 promotes M21 melanoma growth in human skin by regulating tumor cell survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human malignant glioma therapy using anti-alpha(v)beta3 integrin agents.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Safety, pharmacokinetic, and antitumor activity of SU11248, a novel oral multitarget tyrosine kinase inhibitor, in patients with cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted antiangiogenic therapy for cancer using Vitaxin: a humanized monoclonal antibody to the integrin alphavbeta3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue factor, osteopontin, alphavbeta3 integrin expression in microvasculature of gliomas associated with vascular endothelial growth factor expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stepwise in vitro affinity maturation of Vitaxin, an alphav beta3-specific humanized mAb.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrin beta 1- and beta 3-mediated endothelial cell migration is triggered through distinct signaling mechanisms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progression-related expression of beta3 integrin in melanomas and nevi

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I trial of a monoclonal antibody specific for alphavbeta3 integrin (MEDI-522) in patients with advanced malignancies, including an assessment of effect on tumor perfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of tumor angiogenesis in vivo by alphaVbeta3-targeted magnetic resonance imaging

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of integrin alpha V gene expression in human melanoma tumorigenicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-V/beta-3 and alpha-V/beta-5 integrin distribution in neoplastic kidney

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of alpha(v)beta3 integrin is less frequent in ovarian epithelial tumors of low malignant potential in contrast to ovarian carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Renal cell carcinoma: immunohistological investigation of expression of the integrin alpha v beta 3

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pilot study of vitaxin--an angiogenesis inhibitor-in patients with advanced leiomyosarcomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrin activation controls metastasis in human breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrin-mediated signal transduction in human endothelial cells: analysis of tyrosine phosphorylation events

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Approaches to studying cell adhesion molecules in angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiogenesis and antiangiogenic therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of alpha(v)beta(3) in prostate cancer progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo therapy of malignant melanoma by means of antagonists of alphav integrins

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unique ability of integrin alpha(v)beta 3 to support tumor cell arrest under dynamic flow conditions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct targeting of alphavbeta3 integrin on tumor cells with a monoclonal antibody, Abegrin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of coagulation cascade and endothelial cell activation during inhibition of vascular endothelial growth factor/vascular endothelial growth factor receptor pathway in cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistological examination of the relationship between metastatic potential and expression of adhesion molecules and 'selectins' on melanoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrins: versatility, modulation, and signaling in cell adhesion

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrin alpha V beta 3 expression by bone-residing breast cancer metastases

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tensional homeostasis and the malignant phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen

1 reference

https://pubmed.ncbi.nlm.nih.gov/17876527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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