(Q34707738)

4 August 2017

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title

Induction of apoptosis in the prostate by alpha1-adrenoceptor antagonists: a novel effect of "old" drugs (English)

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4 August 2017

Kyprianou N

1

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4 August 2017

Jacobs SC

series ordinal

2

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4 August 2017

publication date

1 August 2000

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4 August 2017

published in

Current urology reports

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4 August 2017

volume

1

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4 August 2017

issue

2

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4 August 2017

page(s)

89-96

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Noradrenaline contractions of human prostate mediated by alpha 1A-(alpha 1c-) adrenoceptor subtype

4 August 2017

cites work

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The metabolism and kinetics of doxazosin in man, mouse, rat and dog.

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The alpha 1-adrenoceptor antagonist profile of doxazosin: preclinical pharmacology

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Peptidergic innervation of the human prostate, seminal vesicle and vas deferens

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12 December 2020

Suppression of human prostate cancer cell growth by alpha1-adrenoceptor antagonists doxazosin and terazosin via induction of apoptosis

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12 December 2020

Doxazosin inhibits proliferation and migration of human vascular smooth-muscle cells independent of alpha1-adrenergic receptor antagonism

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Synthetic activation of caspases: artificial death switches

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Apoptosis and clonogenic cell death in PC3 human prostate cancer cells after treatment with gamma radiation and suramin

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Doxazosin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in mild or moderate hypertension

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12 December 2020

Regulation of vascular smooth muscle growth by alpha 1-adrenoreceptor subtypes in vitro and in situ

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12 December 2020

Alpha-adrenergic blockers for the treatment of benign prostatic hyperplasia

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12 December 2020

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

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12 December 2020

The alpha 1-adrenergic receptor that mediates smooth muscle contraction in human prostate has the pharmacological properties of the cloned human alpha 1c subtype

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12 December 2020

The effects of tamsulosin, a high affinity antagonist at functional alpha 1A- and alpha 1D-adrenoceptor subtypes

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12 December 2020

The pathophysiology of lower urinary tract symptoms in the ageing male population

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12 December 2020

Localization of mRNA and receptor binding sites for the alpha 1a-adrenoceptor subtype in the rat, monkey and human urinary bladder and prostate

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The role of calcium, pH, and cell proliferation in the programmed (apoptotic) death of androgen-independent prostatic cancer cells induced by thapsigargin

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Tamsulosin, the first prostate-selective alpha 1A-adrenoceptor antagonist. Analysis of a multinational, multicentre, open-label study assessing the long-term efficacy and safety in patients with benign prostatic obstruction (symptomatic BPH). Europe

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Non-hormone chemotherapy for prostate cancer: principles of treatment and application to the testing of new drugs.

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Apoptotic versus proliferative activities in human benign prostatic hyperplasia

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12 December 2020

Influence of the alpha1-adrenergic antagonist, doxazosin, on noradrenaline-induced modulation of cytoskeletal proteins in cultured hyperplastic prostatic stromal cells

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Adrenergic regulation of myocardial apoptosis

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Long-term effects on plasma lipids of diet and drugs to treat hypertension. Treatment of Mild Hypertension Study (TOMHS) Research Group.

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Programmed cell death during regression of PC-82 human prostate cancer following androgen ablation

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Adrenergic and Cholinergic Receptors in the Human Prostate, Prostatic Capsule and Bladder Neck

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Heterotrimeric G proteins: organizers of transmembrane signals

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12 December 2020

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12 December 2020

Induction of prostate apoptosis by doxazosin in benign prostatic hyperplasia.

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12 December 2020

Alpha1-adrenoceptor subtypes in the human prostate

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Induction of apoptosis in androgen-independent human prostate cancer cells undergoing thymineless death.

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12 December 2020

Combined antitumor effect of suramin plus irradiation in human prostate cancer cells: the role of apoptosis.

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12 December 2020

Neoadjuvant hormonal therapy improves the therapeutic ratio in patients with bulky prostatic cancer treated with three-dimensional conformal radiation therapy

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12 December 2020

Adverse effects of alpha 1-adrenergic blocking drugs

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12 December 2020

Alpha 1-adrenoceptor antagonists terazosin and doxazosin induce prostate apoptosis without affecting cell proliferation in patients with benign prostatic hyperplasia

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12 December 2020

Doxazosin modifies Bcl-2 and Bax protein expression in the left ventricle of spontaneously hypertensive rats

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12 December 2020

Alpha adrenoceptor blockade in the treatment of benign prostatic hyperplasia: past, present and future

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12 December 2020

Long-term reduction of intimal hyperplasia by the selective alpha-1 adrenergic antagonist doxazosin

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12 December 2020

The response to alpha blockade in benign prostatic hyperplasia is related to the percent area density of prostate smooth muscle

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12 December 2020

A controlled trial of leuprolide with and without flutamide in prostatic carcinoma

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12 December 2020

Activation of programmed cell death in the rat ventral prostate after castration

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12 December 2020

Implication of cell kinetic changes during the progression of human prostatic cancer

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12 December 2020

Pharmacokinetics of terazosin

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12 December 2020

Alpha 1-adrenergic stimulation and beta 2-adrenergic inhibition of DNA synthesis in vascular smooth muscle cells

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12 December 2020

10.1007/S11934-000-0042-0

Identifiers

DOI

1 reference

Dimensions Publication ID

4 August 2017

1044262722

0 references

1 reference