(Q34717067)

4 August 2017

title

A highly productive, whole-cell DERA chemoenzymatic process for production of key lactonized side-chain intermediates in statin synthesis (English)

1 reference

4 August 2017

Matej Ošlaj

1

1 reference

4 August 2017

Jérôme Cluzeau

2

1 reference

4 August 2017

Damir Orkić

3

1 reference

4 August 2017

Gregor Kopitar

4

1 reference

4 August 2017

Peter Mrak

5

1 reference

4 August 2017

Zdenko Casar

6

1 reference

4 August 2017

language of work or name

English

0 references

publication date

7 May 2013

1 reference

4 August 2017

1 reference

4 August 2017

volume

8

1 reference

4 August 2017

issue

5

1 reference

4 August 2017

page(s)

e62250

1 reference

Creative Commons Attribution 4.0 International

4 August 2017

copyright license

start time

7 May 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Regulators of oxidative stress response genes in Escherichia coli and their functional conservation in bacteria

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Pharmacological strategies for lowering LDL cholesterol: statins and beyond

7 July 2018

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Cellular strategies for controlling protein aggregation

7 July 2018

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Enzymatic and whole cell catalysis: finding new strategies for old processes

7 July 2018

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Efficient diacetoxylation of alkenes via Pd(II)/Pd(IV) process with peracetic acid and acetic anhydride

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

A novel whole-cell biocatalyst with NAD+ regeneration for production of chiral chemicals

7 July 2018

1 reference

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Recent progress in stereoselective synthesis with aldolases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Applications of biotransformations and biocatalysis to complexity generation in organic synthesis

7 July 2018

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The locks and keys to industrial biotechnology

7 July 2018

1 reference

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Whole-cell biocatalysts for biodiesel fuel production

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Convergence of Molecular, Modeling, and Systems Approaches for an Understanding of the Escherichia coli Heat Shock Response

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Catalytic asymmetric aldol reactions in aqueous media

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Directed evolution of aldolases for exploitation in synthetic organic chemistry

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Emerging indications for statins: a pluripotent family of agents with several potential applications

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Sequential Aldol Condensation Catalyzed by Hyperthermophilic 2-Deoxy-D-Ribose-5-Phosphate Aldolase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Endothelial dysfunction, oxidative stress and inflammation in atherosclerosis: beneficial effects of statins.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Biocatalysis for pharmaceutical intermediates: the future is now.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Microbial aldolases as C-C bonding enzymes--unknown treasures and new developments

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Statins in stroke: prevention, protection and recovery

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Enantioselective C-C bond synthesis catalysed by enzymes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Effects of statins beyond lipid lowering: potential for clinical benefits.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Growing E. coli to high cell density--a historical perspective on method development

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Advances in biocatalytic synthesis of pharmaceutical intermediates

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Whole organism biocatalysis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Chemoenzymatic synthesis of building blocks for statin side chains

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Analysis of the class I aldolase binding site architecture based on the crystal structure of 2-deoxyribose-5-phosphate aldolase at 0.99A resolution

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Trends and innovations in industrial biocatalysis for the production of fine chemicals.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Directed evolution of aldolases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Development of an efficient, scalable, aldolase-catalyzed process for enantioselective synthesis of statin intermediates

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Enzymatic synthesis and breakdown of desoxyribose phosphate.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Ribosome-tethered molecular chaperones: the first line of defense against protein misfolding?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Dispelling the myths--biocatalysis in industrial synthesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

The production of fine chemicals by biotransformations.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Observation of covalent intermediates in an enzyme mechanism at atomic resolution

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Structural mechanism for statin inhibition of HMG-CoA reductase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

7 July 2018

Industrial biocatalysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Industrial biocatalysis today and tomorrow

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Enzymes for chemical synthesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Biocatalysis for industrial production of fine chemicals

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Production of fine chemicals using biocatalysis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

The oxidation of 2-acetamido-2-deoxyaldoses with aqueous bromine. Two diastereoisomeric 2-acetamido-2,3-dideoxyhex-2-enono-1,4-lactones from 2-acetamido-2-deoxy-d-glucose, -mannose, and -galactose1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

The discovery and development of HMG-CoA reductase inhibitors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

ML-236A, ML-236B, and ML-236C, new inhibitors of cholesterogenesis produced by Penicillium citrinium

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Lactone pathway to statins utilizing the Wittig reaction. The synthesis of rosuvastatin.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

A gift from nature: the birth of the statins

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Organocatalytic reactions with acetaldehyde

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Directed evolution of an industrial biocatalyst: 2-deoxy-D-ribose 5-phosphate aldolase.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Electronic effects on the regio- and enantioselectivity of the asymmetric aminohydroxylation of O-substituted 4-hydroxy-2-butenoates.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

The Catalytic Asymmetric Aldol Reaction.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647077

Calorimetric Insight into Coupling between Functionalized Primary Alkyl Halide and Vinylic Organocuprate Reagent: Experimental Determination of Reaction Enthalpies in the Synthesis of (R)-Ethyl 3-(tert-butyldimethylsilyloxy)hex-5-enoate - a Key Lact

26 October 2018

1 reference

12 December 2020

Reaction of proteins with glutaraldehyde

1 reference

12 December 2020

HMG-CoA reductase inhibitors

1 reference

12 December 2020

Stable and efficient immobilization technique of aldolase under consecutive microwave irradiation at low temperature

1 reference

12 December 2020

Recent Advances in the Chemoenzymatic Synthesis of Carbohydrates and Carbohydrate Mimetics

1 reference

12 December 2020

1 reference

12 December 2020

Life after statin patent expiries

1 reference

12 December 2020

Deoxyribose aldolase from Lactobacillus plantarum

1 reference

12 December 2020

Fluorinated carbohydrates as potential plasma membrane modifiers. Synthesis of 4- and 6-fluoro derivatives of 2-acetamido-2-deoxy-D-hexopyranoses

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0062250

Identifiers

DOI

1 reference

release_wrvux4qaera6hlp55hicgphjw4

4 August 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/wrvux4qaera6hlp55hicgphjw4

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3647077

1 reference

4 August 2017

1 reference